Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology

por Medema, Marnix H.
Publicado 2018

Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways

por Medema, Marnix H., Osbourn, Anne
Publicado 2016

Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast

por Medema, Marnix H., Takano, Eriko, Breitling, Rainer
Publicado 2013

Whokaryote: distinguishing eukaryotic and prokaryotic contigs in metagenomes based on gene structure

por Pronk, Lotte J.U., Medema, Marnix H.
Publicado 2022

Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order

por Gaba, Sonam, Kumari, Abha, Medema, Marnix, Kaushik, Rajeev
Publicado 2020

Benefiting from big data in natural products: importance of preserving foundational skills and prioritizing data quality

por Cech, Nadja B., Medema, Marnix H., Clardy, Jon
Publicado 2021

Genome-based exploration of the specialized metabolic capacities of the genus Rhodococcus

por Ceniceros, Ana, Dijkhuizen, Lubbert, Petrusma, Mirjan, Medema, Marnix H.
Publicado 2017

luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria

por Brotherton, Carolyn A., Medema, Marnix H., Greenberg, E. Peter
Publicado 2018

A standardized workflow for submitting data to the Minimum Information about a Biosynthetic Gene cluster (MIBiG) repository: prospects for research-based educational experiences

por Epstein, Samuel C., Charkoudian, Louise K., Medema, Marnix H.
Publicado 2018

Computational genomic discovery of diverse gene clusters harbouring Fe-S flavoenzymes in anaerobic gut microbiota

por Pascal Andreu, Victòria, Fischbach, Michael A., Medema, Marnix H.
Publicado 2020

Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters

por Blin, Kai, Kim, Hyun Uk, Medema, Marnix H, Weber, Tilmann
Publicado 2017

PIKAChU: a Python-based informatics kit for analysing chemical units

por Terlouw, Barbara R., Vromans, Sophie P. J. M., Medema, Marnix H.
Publicado 2022

A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis

por Medema, Marnix H., Cimermancic, Peter, Sali, Andrej, Takano, Eriko, Fischbach, Michael A.
Publicado 2014

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

por Blin, Kai, Medema, Marnix H., Kottmann, Renzo, Lee, Sang Yup, Weber, Tilmann
Publicado 2017

BiG-FAM: the biosynthetic gene cluster families database

por Kautsar, Satria A, Blin, Kai, Shaw, Simon, Weber, Tilmann, Medema, Marnix H
Publicado 2020

The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes

por Blin, Kai, Shaw, Simon, Kautsar, Satria A, Medema, Marnix H, Weber, Tilmann
Publicado 2020

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

por Röttig, Marc, Medema, Marnix H., Blin, Kai, Weber, Tilmann, Rausch, Christian, Kohlbacher, Oliver
Publicado 2011

Enhanced correlation-based linking of biosynthetic gene clusters to their metabolic products through chemical class matching

por Louwen, Joris J. R., Medema, Marnix H., van der Hooft, Justin J. J.
Publicado 2023

MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models

por Zakrzewski, Piotr, Medema, Marnix H., Gevorgyan, Albert, Kierzek, Andrzej M., Breitling, Rainer, Takano, Eriko
Publicado 2012

Draft Genome Sequence of a Porcine Commensal, Rothia nasimurium, Encoding a Nonribosomal Peptide Synthetase Predicted To Produce the Ionophore Antibiotic Valinomycin

por Gaiser, Rogier A., Medema, Marnix H., Kleerebezem, Michiel, van Baarlen, Peter, Wells, Jerry M.
Publicado 2017