Molecular basis underlying resistance to Mps1/TTK inhibitors

por Koch, A, Maia, A, Janssen, A, Medema, R H
Publicado 2016

Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora

por Bruinsma, W, Aprelia, M, García-Santisteban, I, Kool, J, Xu, Y J, Medema, R H
Publicado 2017

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence

por Littler, D. R., Alvarez-Fernández, M., Stein, A., Hibbert, R. G., Heidebrecht, T., Aloy, P., Medema, R. H., Perrakis, A.
Publicado 2010

Persistent repair intermediates induce senescence

por Feringa, F. M., Raaijmakers, J. A., Hadders, M. A., Vaarting, C., Macurek, L., Heitink, L., Krenning, L., Medema, R. H.
Publicado 2018

RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment

por Kongsema, M, Zona, S, Karunarathna, U, Cabrera, E, Man, E P S, Yao, S, Shibakawa, A, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
Publicado 2016

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance

por Khongkow, P, Gomes, A R, Gong, C, Man, E P S, Tsang, J W-H, Zhao, F, Monteiro, L J, Coombes, R C, Medema, R H, Khoo, U S, Lam, E W-F
Publicado 2016

OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance

por Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
Publicado 2016