Yin and Yang of mesenchymal stem cells and aplastic anemia

por Broglie, Larisa, Margolis, David, Medin, Jeffrey A
Publicado 2017

Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency

por Yu, Fabian P. S., Dworski, Shaalee, Medin, Jeffrey A.
Publicado 2018

Acid ceramidase deficiency: Farber disease and SMA-PME

por Yu, Fabian P. S., Amintas, Samuel, Levade, Thierry, Medin, Jeffrey A.
Publicado 2018

The Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis Offers Efficient Bystander Cell Killing for Suicide Gene Therapy of Cancer

por Sato, Takeya, Neschadim, Anton, Lavie, Arnon, Yanagisawa, Teruyuki, Medin, Jeffrey A.
Publicado 2013

Implementation of high-throughput screening for Fabry disease in Toronto dialysis patients

por Rasaiah, Vanessa I., Underwood, John P., Oreopoulos, Dimitrios G., Medin, Jeffrey A.
Publicado 2008

Development of Novel Immunotherapies for Multiple Myeloma

por Al-Hujaily, Ensaf M., Oldham, Robyn A. A., Hari, Parameswaran, Medin, Jeffrey A.
Publicado 2016

Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system

por Nomura, Ryosuke, Sato, Takeya, Sato, Yuka, Medin, Jeffrey A., Kushimoto, Shigeki, Yanagisawa, Teruyuki
Publicado 2017

Skin inflammation and impaired adipogenesis in a mouse model of acid ceramidase deficiency

por Rybova, Jitka, Kuchar, Ladislav, Sikora, Jakub, McKillop, William M., Medin, Jeffrey A.
Publicado 2022

Acid Ceramidase Deficiency: Bridging Gaps between Clinical Presentation, Mouse Models, and Future Therapeutic Interventions

por Kleynerman, Annie, Rybova, Jitka, Faber, Mary L., McKillop, William M., Levade, Thierry, Medin, Jeffrey A.
Publicado 2023

Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways

por Wang, James CM, Felizardo, Tânia C, Au, Bryan CY, Fowler, Daniel H, Dekaban, Gregory A, Medin, Jeffrey A
Publicado 2013

Anti-Leukemia Activity of In Vitro-Expanded Human Gamma Delta T Cells in a Xenogeneic Ph(+) Leukemia Model

por Siegers, Gabrielle M., Felizardo, Tania C., Mathieson, A. Mark, Kosaka, Yoko, Wang, Xing-Hua, Medin, Jeffrey A., Keating, Armand
Publicado 2011

Sarcoma IL-12 overexpression facilitates NK cell immunomodulation

por Rademacher, Mary Jo, Cruz, Anahi, Faber, Mary, Oldham, Robyn A. A., Wang, Dandan, Medin, Jeffrey A., Schloemer, Nathan J.
Publicado 2021

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice

por He, Xingxuan, Dworski, Shaalee, Zhu, Changzhi, DeAngelis, Victor, Solyom, Alex, Medin, Jeffrey A., Simonaro, Calogera M., Schuchman, Edward H.
Publicado 2017

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice

por Fougerat, Anne, Pan, Xuefang, Smutova, Victoria, Heveker, Nikolaus, Cairo, Christopher W., Issad, Tarik, Larrivée, Bruno, Medin, Jeffrey A., Pshezhetsky, Alexey V.
Publicado 2018

Discovery and validation of surface N-glycoproteins in MM cell lines and patient samples uncovers immunotherapy targets

por Oldham, Robyn A A, Faber, Mary L, Keppel, Theodore R, Buchberger, Amanda R, Waas, Matthew, Hari, Parameswaran, Gundry, Rebekah L, Medin, Jeffrey A
Publicado 2020

Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders

por Nagree, Murtaza S, Felizardo, Tania C, Faber, Mary L, Rybova, Jitka, Rupar, C Anthony, Foley, S Ronan, Fuller, Maria, Fowler, Daniel H, Medin, Jeffrey A
Publicado 2022

Localized interleukin-12 delivery for immunotherapy of solid tumours

por Wei, Louis Z, Xu, Yixin, E Nelles, Megan, Furlonger, Caren, Wang, James CM, Di Grappa, Marco A, Khokha, Rama, Medin, Jeffrey A, Paige, Christopher J
Publicado 2013

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML

por Huang, Ju, Liu, Yuanfeng, Au, Bryan C, Barber, Dwayne L, Arruda, Andrea, Schambach, Axel, Rothe, Michael, Minden, Mark D, Paige, Christopher J, Medin, Jeffrey A
Publicado 2016

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging

por Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A., Medin, Jeffrey A., Drake, Richard R.
Publicado 2014

Interleukin-15 in cancer immunotherapy: IL-15 receptor complex versus soluble IL-15 in a cancer cell-delivered murine leukemia model

por Berger, Alexandra, Colpitts, Sarah J., Seabrook, Melanie S. S., Furlonger, Caren L., Bendix, Maura B., Moreau, Joshua M., McKillop, William M., Medin, Jeffrey A., Paige, Christopher J.
Publicado 2019