CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort

por Kitzmiller, Joseph P., Luzum, Jasmine A., Baldassarre, Damiano, Krauss, Ronald M., Medina, Marisa W.
Publicado 2014

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation

por Kim, Kyungpil, Bolotin, Eugene, Theusch, Elizabeth, Huang, Haiyan, Medina, Marisa W, Krauss, Ronald M
Publicado 2014

Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

por Theusch, Elizabeth, Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Publicado 2020

Development and application of an algorithm for statin-induced myopathy based on electronic health record-derived structured elements

por Oni-Orisan, Akinyemi, Lu, Meng, Peng, Jonathan A., Krauss, Ronald M., Iribarren, Carlos, Medina, Marisa W.
Publicado 2023

GeneFishing to reconstruct context specific portraits of biological processes

por Liu, Ke, Theusch, Elizabeth, Zhou, Yun, Ashuach, Tal, Dose, Andrea C., Bickel, Peter J., Medina, Marisa W., Huang, Haiyan
Publicado 2019

RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

por Medina, Marisa W., Theusch, Elizabeth, Naidoo, Devesh, Bauzon, Frederick, Stevens, Kristen, Mangravite, Lara M., Kuang, Yu-Lin, Krauss, Ronald M.
Publicado 2012

Correction: RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

por Medina, Marisa W., Theusch, Elizabeth, Naidoo, Devesh, Bauzon, Frederick, Stevens, Kristen, Mangravite, Lara M., Kuang, Yu-Lin, Krauss, Ronald M.
Publicado 2013

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort

por Haldar, Tanushree, Oni-Orisan, Akinyemi, Hoffmann, Thomas J., Schaefer, Catherine, Iribarren, Carlos, Krauss, Ronald M., Medina, Marisa W., Risch, Neil
Publicado 2022

SUGP1 is a novel regulator of cholesterol metabolism

por Kim, Mee J., Yu, Chi-Yi, Theusch, Elizabeth, Naidoo, Devesh, Stevens, Kristen, Kuang, Yu-Lin, Schuetz, Erin, Chaudhry, Amarjit S., Medina, Marisa W.
Publicado 2016

ZNF542P is a pseudogene associated with LDL response to simvastatin treatment

por Kim, Kyungpil, Theusch, Elizabeth, Kuang, Yu-Lin, Dose, Andrea, Mitchel, Katrina, Cubitt, Celia, Chen, Yii-Der I., Krauss, Ronald M., Medina, Marisa W.
Publicado 2018

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change

por Oni-Orisan, Akinyemi, Haldar, Tanushree, Ranatunga, Dilrini K., Medina, Marisa W., Schaefer, Catherine, Krauss, Ronald M., Iribarren, Carlos, Risch, Neil, Hoffmann, Thomas J.
Publicado 2020

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation

por Kuang, Yu-Lin, Munoz, Antonio, Nalula, Gilbert, Santostefano, Katherine E., Sanghez, Valentina, Sanchez, Gabriela, Terada, Naohiro, Mattis, Aras N., Iacovino, Michelina, Iribarren, Carlos, Krauss, Ronald M., Medina, Marisa W.
Publicado 2019

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease

por Muñoz, Antonio, Theusch, Elizabeth, Kuang, Yu-Lin, Nalula, Gilbert, Peaslee, Caitlin, Dorlhiac, Gabriel, Landry, Markita P., Streets, Aaron, Krauss, Ronald M., Iribarren, Carlos, Mattis, Aras N., Medina, Marisa W.
Publicado 2022

A large electronic health record-based genome-wide study of serum lipids

por Hoffmann, Thomas J, Theusch, Elizabeth, Haldar, Tanushree, Ranatunga, Dilrini K, Jorgenson, Eric, Medina, Marisa W, Kvale, Mark N, Kwok, Pui-Yan, Schaefer, Catherine, Krauss, Ronald M, Iribarren, Carlos, Risch, Neil
Publicado 2018

A gene–diet interaction controlling relative intake of dietary carbohydrates and fats

por Nelson, Nnamdi G., Wu, Lili, Maier, Matthew T., Lam, Diana, Cheang, Rachel, Alba, Diana, Huang, Alyssa, Neumann, Drexel A., Hill, Tess, Vagena, Eirini, Barsh, Gregory S., Medina, Marisa W., Krauss, Ronald M., Koliwad, Suneil K., Xu, Allison W.
Publicado 2022

Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response

por Theusch, Elizabeth, Ting, Flora Y., Qin, Yuanyuan, Stevens, Kristen, Naidoo, Devesh, King, Sarah M., Yang, Neil, Orr, Joseph, Han, Brenda Y., Cyster, Jason G., Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Publicado 2023

A polymorphism in HLA-G modifies statin benefit in asthma

por Naidoo, Devesh, Wu, Ann C, Brilliant, Murray H, Denny, Joshua, Ingram, Christie, Kitchner, Terrie E, Linneman, James G, McGeachie, Michael J, Roden, Dan M, Shaffer, Christian M, Shah, Anushi, Weeke, Peter, Weiss, Scott T, Xu, Hua, Medina, Marisa W
Publicado 2014

A unified framework identifies novel links between plasma lipids and diseases from electronic medical records across large-scale cohorts

por Veturi, Yogasudha, Lucas, Anastasia, Bradford, Yuki, Hui, Daniel, Dudek, Scott, Theusch, Elizabeth, Verma, Anurag, Miller, Jason E., Kullo, Iftikhar, Hakonarson, Hakon, Sleiman, Patrick, Schaid, Daniel, Stein, Charles M., Edwards, Digna R. Velez, Feng, QiPing, Wei, Wei-Qi, Medina, Marisa W., Krauss, Ronald, Hoffmann, Thomas J., Risch, Neil, Voight, Benjamin F., Rader, Daniel J., Ritchie, Marylyn D.
Publicado 2021

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

por Mangravite, Lara M., Engelhardt, Barbara E., Medina, Marisa W., Smith, Joshua D., Brown, Christopher D., Chasman, Daniel I., Mecham, Brigham H., Howie, Bryan, Shim, Heejung, Naidoo, Devesh, Feng, QiPing, Rieder, Mark J., Chen, Y-D I., Rotter, Jerome I., Ridker, Paul M., Hopewell, Jemma C., Parish, Sarah, Armitage, Jane, Collins, Rory, Wilke, Russell A., Nickerson, Deborah A., Stephens, Matthew, Krauss, Ronald M.
Publicado 2013