Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance

por Medina-Vera, Dina, López-Gambero, Antonio Jesús, Navarro, Juan Antonio, Sanjuan, Carlos, Baixeras, Elena, Decara, Juan, de Fonseca, Fernando Rodríguez
Publicado 2023

The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer’s Disease in App(NL-G-F) Knock-In Mice

por Medina-Vera, Dina, Zhao, Hongjing, Bereczki, Erika, Rosell-Valle, Cristina, Shimozawa, Makoto, Chen, Gefei, de Fonseca, Fernando Rodríguez, Nilsson, Per, Tambaro, Simone
Publicado 2023

Translational potential of synaptic alterations in Alzheimer’s disease patients and amyloid precursor protein knock-in mice

por Medina-Vera, Dina, Enache, Daniela, Tambaro, Simone, Abuhashish, Ethar, Rosell-Valle, Cristina, Winblad, Bengt, Rodríguez de Fonseca, Fernando, Bereczki, Erika, Nilsson, Per
Publicado 2023

A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer’s Disease, the 5XFAD Mouse

por López-Gambero, Antonio J., Rosell-Valle, Cristina, Medina-Vera, Dina, Navarro, Juan Antonio, Vargas, Antonio, Rivera, Patricia, Sanjuan, Carlos, Rodríguez de Fonseca, Fernando, Suárez, Juan
Publicado 2021

Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer’s Disease in a Preclinical Model: A Therapeutic Opportunity

por Medina-Vera, Dina, Rosell-Valle, Cristina, López-Gambero, Antonio J., Navarro, Juan A., Zambrana-Infantes, Emma N., Rivera, Patricia, Santín, Luis J., Suarez, Juan, Rodríguez de Fonseca, Fernando
Publicado 2020

D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats

por Navarro, Juan A., Decara, Juan, Medina-Vera, Dina, Tovar, Rubén, Suarez, Juan, Pavón, Javier, Serrano, Antonia, Vida, Margarita, Gutierrez-Adan, Alfonso, Sanjuan, Carlos, Baixeras, Elena, de Fonseca, Fernando Rodríguez
Publicado 2020

Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol

por Medina-Vera, Dina, Navarro, Juan Antonio, Tovar, Rubén, Rosell-Valle, Cristina, Gutiérrez-Adan, Alfonso, Ledesma, Juan Carlos, Sanjuan, Carlos, Pavón, Francisco Javier, Baixeras, Elena, Rodríguez de Fonseca, Fernando, Decara, Juan
Publicado 2021

Endocrine and Metabolic Impact of Oral Ingestion of a Carob-Pod-Derived Natural-Syrup-Containing D-Pinitol: Potential Use as a Novel Sweetener in Diabetes

por Navarro, Juan A., Decara, Juan, Medina-Vera, Dina, Tovar, Ruben, Lopez-Gambero, Antonio J., Suarez, Juan, Pavón, Francisco Javier, Serrano, Antonia, de Ceglia, Marialuisa, Sanjuan, Carlos, Baltasar, Yolanda Alfonso, Baixeras, Elena, Rodríguez de Fonseca, Fernando
Publicado 2022

d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?

por Medina‐Vera, Dina, Navarro, Juan Antonio, Rivera, Patricia, Rosell‐Valle, Cristina, Gutiérrez‐Adán, Alfonso, Sanjuan, Carlos, López‐Gambero, Antonio Jesús, Tovar, Rubén, Suárez, Juan, Pavón, Francisco Javier, Baixeras, Elena, Decara, Juan, Rodríguez de Fonseca, Fernando
Publicado 2022

Pharmacokinetics and Endocrine Effects of an Oral Dose of D-Pinitol in Human Fasting Healthy Volunteers

por Navarro, Juan A., Díaz, Caridad, Decara, Juan, Medina-Vera, Dina, Lopez-Gambero, Antonio J., Suarez, Juan, Pavón, Francisco Javier, Serrano, Antonia, Vargas, Antonio, Gavito, Ana Luisa, Porras-Perales, Oscar, Aranda, Jesús, Vicente, Francisca, Sanjuan, Carlos, Baixeras, Elena, de Fonseca, Fernando Rodríguez
Publicado 2022

Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus

por Sánchez-Quintero, María José, Delgado, Josué, Medina-Vera, Dina, Becerra-Muñoz, Víctor M., Queipo-Ortuño, María Isabel, Estévez, Mario, Plaza-Andrades, Isaac, Rodríguez-Capitán, Jorge, Sánchez, Pedro L., Crespo-Leiro, Maria G., Jiménez-Navarro, Manuel F., Pavón-Morón, Francisco Javier
Publicado 2022

Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice

por Sánchez-Quintero, María José, Delgado, Josué, Martín Chaves, Laura, Medina-Vera, Dina, Murri, Mora, Becerra-Muñoz, Víctor M., Estévez, Mario, Crespo-Leiro, María G., Paz López, Guillermo, González-Jiménez, Andrés, A. G. Ranea, Juan, Queipo-Ortuño, María Isabel, Plaza-Andrades, Isaac, Rodríguez-Capitán, Jorge, Pavón-Morón, Francisco Javier, Jiménez-Navarro, Manuel F.
Publicado 2023

Prognostic stratification of older patients with multivessel coronary artery disease treated with percutaneous transluminal coronary angioplasty based on clinical and biochemical m...

por Carmona-Segovia, Ada del Mar, Doncel-Abad, María Victoria, Becerra-Muñoz, Víctor M, Rodríguez-Capitán, Jorge, Sabatel-Pérez, Fernando, Flores-López, María, Sánchez-Quintero, María José, Medina-Vera, Dina, Molina-Ramos, Ana Isabel, El Bekay, Rajaa, Morales-Asencio, José Miguel, Angullo-Gómez, María, García-Rodríguez, Luis, Palma-Martí, Lucía, Pavón-Morón, Francisco Javier, Jiménez-Navarro, Manuel F.
Publicado 2022