An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment

por Martín-Escolano, Javier, Marín, Clotilde, Rosales, María J., Tsaousis, Anastasios D., Medina-Carmona, Encarnación, Martín-Escolano, Rubén
Publicado 2022

Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism

por Medina-Carmona, Encarnación, Neira, Jose L., Salido, Eduardo, Fuchs, Julian E., Palomino-Morales, Rogelio, Timson, David J., Pey, Angel L.
Publicado 2017

Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

por Medina-Carmona, Encarnación, Palomino-Morales, Rogelio J., Fuchs, Julian E., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Salido, Eduardo, Timson, David J., Pey, Angel L.
Publicado 2016

Erratum: Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

por Medina-Carmona, Encarnación, Palomino-Morales, Rogelio J., Fuchs, Julian E., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Salido, Eduardo, Timson, David J., Pey, Angel L.
Publicado 2016

Structure-based discovery and in vitro validation of inhibitors of chloride intracellular channel 4 protein

por Olotu, Fisayo, Medina-Carmona, Encarnacion, Serrano-Sanchez, Angela, Ossa, Felipe, El-Hamdaoui, Abdelaziz, Bishop, Özlem Tastan, Ortega-Roldan, Jose L., Abdul-Salam, Vahitha B.
Publicado 2022

Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate

por Medina-Carmona, Encarnación, Gutierrez-Rus, Luis I, Manssour-Triedo, Fadia, Newton, Matilda S, Gamiz-Arco, Gloria, Mota, Antonio J, Reiné, Pablo, Cuerva, Juan Manuel, Ortega-Muñoz, Mariano, Andrés-León, Eduardo, Ortega-Roldan, Jose Luis, Seelig, Burckhard, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M
Publicado 2023