Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

por Mak, Jeffrey Y. W., Xu, Weijun, Reid, Robert C., Corbett, Alexandra J., Meehan, Bronwyn S., Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong, Fairlie, David P.
Publicado 2017

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

por Reantragoon, Rangsima, Kjer-Nielsen, Lars, Patel, Onisha, Chen, Zhenjun, Illing, Patricia T., Bhati, Mugdha, Kostenko, Lyudmila, Bharadwaj, Mandvi, Meehan, Bronwyn, Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Publicado 2012

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

por Hinks, Timothy S.C., Marchi, Emanuele, Jabeen, Maisha, Olshansky, Moshe, Kurioka, Ayako, Pediongco, Troi J., Meehan, Bronwyn S., Kostenko, Lyudmila, Turner, Stephen J., Corbett, Alexandra J., Chen, Zhenjun, Klenerman, Paul, McCluskey, James
Publicado 2019

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

por Rahimpour, Azad, Koay, Hui Fern, Enders, Anselm, Clanchy, Rhiannon, Eckle, Sidonia B.G., Meehan, Bronwyn, Chen, Zhenjun, Whittle, Belinda, Liu, Ligong, Fairlie, David P., Goodnow, Chris C., McCluskey, James, Rossjohn, Jamie, Uldrich, Adam P., Pellicci, Daniel G., Godfrey, Dale I.
Publicado 2015

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

por Eckle, Sidonia B.G., Birkinshaw, Richard W., Kostenko, Lyudmila, Corbett, Alexandra J., McWilliam, Hamish E.G., Reantragoon, Rangsima, Chen, Zhenjun, Gherardin, Nicholas A., Beddoe, Travis, Liu, Ligong, Patel, Onisha, Meehan, Bronwyn, Fairlie, David P., Villadangos, Jose A., Godfrey, Dale I., Kjer-Nielsen, Lars, McCluskey, James, Rossjohn, Jamie
Publicado 2014

The balance of interleukin‐12 and interleukin‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection

por Wang, Huimeng, Nelson, Adam G, Wang, Bingjie, Zhao, Zhe, Lim, Xin Yi, Shi, Mai, Meehan, Lucy J, Jia, Xiaoxiao, Kedzierska, Katherine, Meehan, Bronwyn S, Eckle, Sidonia BG, Souter, Michael NT, Pediongco, Troi J, Mak, Jeffrey YW, Fairlie, David P, McCluskey, James, Wang, Zhongfang, Corbett, Alexandra J, Chen, Zhenjun
Publicado 2022

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

por Reantragoon, Rangsima, Corbett, Alexandra J., Sakala, Isaac G., Gherardin, Nicholas A., Furness, John B., Chen, Zhenjun, Eckle, Sidonia B.G., Uldrich, Adam P., Birkinshaw, Richard W., Patel, Onisha, Kostenko, Lyudmila, Meehan, Bronwyn, Kedzierska, Katherine, Liu, Ligong, Fairlie, David P., Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James, Kjer-Nielsen, Lars
Publicado 2013

Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo

por Nelson, Adam G., Wang, Huimeng, Dewar, Phoebe M., Eddy, Eleanor M., Li, Songyi, Lim, Xin Yi, Patton, Timothy, Zhou, Yuchen, Pediongco, Troi J., Meehan, Lucy J., Meehan, Bronwyn S., Mak, Jeffrey Y. W., Fairlie, David P., Stent, Andrew W., Kjer-Nielsen, Lars, McCluskey, James, Eckle, Sidonia B. G., Corbett, Alexandra J., Souter, Michael N. T., Chen, Zhenjun
Publicado 2023

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

por Zhao, Zhe, Wang, Huimeng, Shi, Mai, Zhu, Tianyuan, Pediongco, Troi, Lim, Xin Yi, Meehan, Bronwyn S., Nelson, Adam G., Fairlie, David P., Mak, Jeffrey Y. W., Eckle, Sidonia B. G., de Lima Moreira, Marcela, Tumpach, Carolin, Bramhall, Michael, Williams, Cameron G., Lee, Hyun Jae, Haque, Ashraful, Evrard, Maximilien, Rossjohn, Jamie, McCluskey, James, Corbett, Alexandra J., Chen, Zhenjun
Publicado 2021

MAIT cells contribute to protection against lethal influenza infection in vivo

por van Wilgenburg, Bonnie, Loh, Liyen, Chen, Zhenjun, Pediongco, Troi J., Wang, Huimeng, Shi, Mai, Zhao, Zhe, Koutsakos, Marios, Nüssing, Simone, Sant, Sneha, Wang, Zhongfang, D’Souza, Criselle, Jia, Xiaoxiao, Almeida, Catarina F., Kostenko, Lyudmila, Eckle, Sidonia B. G., Meehan, Bronwyn S., Kallies, Axel, Godfrey, Dale I., Reading, Patrick C., Corbett, Alexandra J., McCluskey, James, Klenerman, Paul, Kedzierska, Katherine, Hinks, Timothy S. C.
Publicado 2018

MAIT cells protect against pulmonary Legionella longbeachae infection

por Wang, Huimeng, D’Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C., Chen, Zhenjun
Publicado 2018

CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells

por Souter, Michael N.T., Awad, Wael, Li, Shihan, Pediongco, Troi J., Meehan, Bronwyn S., Meehan, Lucy J., Tian, Zehua, Zhao, Zhe, Wang, Huimeng, Nelson, Adam, Le Nours, Jérôme, Khandokar, Yogesh, Praveena, T., Wubben, Jacinta, Lin, Jie, Sullivan, Lucy C., Lovrecz, George O., Mak, Jeffrey Y.W., Liu, Ligong, Kostenko, Lyudmila, Kedzierska, Katherine, Corbett, Alexandra J., Fairlie, David P., Brooks, Andrew G., Gherardin, Nicholas A., Uldrich, Adam P., Chen, Zhenjun, Rossjohn, Jamie, Godfrey, Dale I., McCluskey, James, Pellicci, Daniel G., Eckle, Sidonia B.G.
Publicado 2022