The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila

por Gregory, Jenna M., Barros, Teresa P., Meehan, Sarah, Dobson, Christopher M., Luheshi, Leila M.
Publicado 2012

Site-Directed Mutations in the C-Terminal Extension of Human αB-Crystallin Affect Chaperone Function and Block Amyloid Fibril Formation

por Treweek, Teresa M., Ecroyd, Heath, Williams, Danielle M., Meehan, Sarah, Carver, John A., Walker, Mark J.
Publicado 2007

The interaction of unfolding α-lactalbumin and malate dehydrogenase with the molecular chaperone αB-crystallin: a light and X-ray scattering investigation

por Regini, Justyn W., Ecroyd, Heath, Meehan, Sarah, Bremmell, Kristen, Clarke, Matthew J., Lammie, Donna, Wess, Tim, Carver, John A.
Publicado 2010

The Amyloid Fibril-Forming β-Sheet Regions of Amyloid β and α-Synuclein Preferentially Interact with the Molecular Chaperone 14-3-3ζ

por Williams, Danielle M., Thorn, David C., Dobson, Christopher M., Meehan, Sarah, Jackson, Sophie E., Woodcock, Joanna M., Carver, John A.
Publicado 2021

Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains

por Miller, Alyssa, Wei, Jiapeng, Meehan, Sarah, Dobson, Christopher M., Welland, Mark E., Klenerman, David, Vendruscolo, Michele, Ruggeri, Francesco Simone, Knowles, Tuomas P. J.
Publicado 2023

The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation

por Waudby, Christopher A., Knowles, Tuomas P.J., Devlin, Glyn L., Skepper, Jeremy N., Ecroyd, Heath, Carver, John A., Welland, Mark E., Christodoulou, John, Dobson, Christopher M., Meehan, Sarah
Publicado 2010

Single Molecule Characterization of the Interactions between Amyloid-β Peptides and the Membranes of Hippocampal Cells

por Narayan, Priyanka, Ganzinger, Kristina A., McColl, James, Weimann, Laura, Meehan, Sarah, Qamar, Seema, Carver, John A., Wilson, Mark R., St. George-Hyslop, Peter, Dobson, Christopher M., Klenerman, David
Publicado 2013

The Use of Different Sepsis Risk Stratification Tools on the Wards and in Emergency Departments Uncovers Different Mortality Risks: Results of the Three Welsh National Multicenter...

por Unwin, Harry J. A., Kopczynska, Maja, Pugh, Richard, Tan, Laura J. P., Subbe, Christian P., Ellis, Gemma, Morgan, Paul, Havalda, Peter, Sharif, Ben, Burke, John, Szakmany, Tamas, Hobrok, Maria, Thomas, Moriah, Burden, Annie, Youssef, Nadia, Carnegie, Katherine, Colling-Sylvester, Helena, Logier, Natasha, Alsaeed, Meshari, Williams, Hannah, Ayob, Arfa, Farzana, Nor, Parida, Sweta, Lawson, David, Evans, Emily, Davis, Laura Jane, Atkins, Billie, Davies, Llywela Wyn, Sanders-Crook, Lee, Seal, Steffan Treharne, Cains, Alice, Pugh, Richard, Crisp, Katy, Venning, Sarah, Sykes, Ella, Narine, Stephanie, Parry, Georgia, Dillon, Emily Angela, Siah, Qi Zhuang, Yang, Ting, Jones, Tyler, Thara, Parvathi, Wood, Emma, Wirt, Lara, Pier, Georgina St, Betts, Richard, Mitsaki, Kyriaki, Tachweed Pierce, Mari, Davies, Sioned, Hafouda, Yakeen, Ifan, Erin, Lacey, Grace, Mitchell, Francesca, Lynch, John, Mazur, Michal, D’Souza, Lezia, Ponting, Bethan, Lau, Terrance, Kerrigan, Ruairidh, Morgan, Lucy, Vindla, Roshan, Zeicu, Claudia, James, Becky, Ariff, Amirah Amin, Wan Azzlan, Wan Binti, Collins, Charlotte, Wickens, Elizabeth, Norbee, Alisa, Zulkefli, Aliya, Haddock, Thomas, Thomas, Megan, Lee, Matthew, Cynan, Miriam, Nik Azis, Nik-Syakirah, Hay, Imogen, Russell, Catherine, Vreugdenhil, Margriet, Abdimalik, Mustafa, Davies, Joseph, Havalda, Peter, Evans, Angharad, Robertson, Kate, Gitau, Grace, Gruber, Mei-yin, Telford, Thomas, Qarout, Anas, Nandra, Naomi, Garrard, Hannah, Cutler, James, Tammy Jones, Rhiannon, Prideaux, Amy, Spence, Timothy, Hardie, Sarah, Seymour, Harriet, Willis, Sam, Warlow, Matthew, Thanthilla, Shanali, Downs, Thomas, Foley, Nina, McKeown, Chad, Dandawate, Akshita, Shayan-Arani, Holleh, Taylor, Ellie, Kyriakides, Oliver, Price, Rachel, Haf Mackey, Ffion, Haines, Emily, Chun, Samuel, Vignarajah, Nilarnti, Chamberlain, Tessa, Zhao, Dongying, Tantirige, Nayanatara Nadeesha T, Dennehey, Naomi, Evans, Georgina, Watts, John, Battle, Ceri, Jones, Ryan, Jones, Selina, James, Charlotte, O’Hanlon, James, Bridges, Isabella, Hughes, Bethany, Polchar, Leo, Bisson, Elise, Mykura, Charlotte, Money, Lara, McKenna, Joshua, Kinsman, Sarah, Hanna, Demiana, Baker, Emily, Sprague, Harrison, Sharma, Liam, Pontin, Tom, Shore, Emma, Hughes, Tamara, Nightingale, Sam, Baby, Philby, Shield, Matthew, Cross, Alice, Boss, Jenna, Ross, Olivia, Ashton, George, Pandit, Kimaya, Davies, Daniel, Garbutt, Cameron, Johnston, Charlotte, Cox, Marcus, Roberts, Chantal, Waller, Alessia, Heekin, Laura, Wang, Kathy, Church, Rhianna, Patel, Shrina, Broderick, Marianne, Whillis, Hannah, Hathaway, Daniel Craig, Yildirim, Emel, Atkins, Caitlin, Walters, Elin, Durie, Carys, Hamilton Sinnerton, Robert James, Tanner, Benjamin, Abreu, Julimar, Bashir, Kiran, Hamlyn, Vincent, Tee, Amelia, Hinchcliffe, Zoe Ann, Otto, Rita, Covell, Georgie, Stone, Megan, Maidman, Victoria, Godfray, Katherine, Caradine, Rhidian, Beetham, Hannah, Anomneze-Collins, Adanna Nicole, Tan, Jeanette, Abdelrazik, Yasmina, Khan, Azizah, Malik, Nabihah, Clack, Aidan, Oliva, Lewis, Thomas, Tyler, Mounce, Adam George, Ramjeeawon, Anoopama, Mtunzi, Ndaba, Soppitt, Duncan, Hale, Jay, Wellington, Jack, Buchanan Ross, Robert, Lis, Danielle, Parsonson, Rebecca, Joseph-Gubra, Jude, Arunthavarajah, Ajitha, Nicholas, Jessica, Harris, Aaron, Atkinson, Henry, Webster, Jessica, Burnett, Tim, Raffan Gowar, Josephine, DeFriend, Sam, Whitaker, Jasmine, Beasant, Elizabeth, Macchiavello, Luis, Usman, Danyal, Mahdi, Abdullah, Tze Shan, Tiffany Ye, Savill, Nick, Gee, Jennifer, Hodges, Lizzie, Desai, Ami, Rossiter, Hannah, Taylor, Matthew, Pinto, Kevin, Hartley, Eleanor, Emanuel, Oscar, Long, Rhiannon, Selby, Megan, Wardle, Elilis, Urquhart, Alexandra, Barrington, Jack, Ashman, Matthew, Adcock, Elizabeth, Dickinson, Amelia, Jordache, Rebecca, El Alaoui, Rym Chafai, Stovold, Sophie, Vickery, Sam, Jones, Nia, O’Donnell, Alice, Cuthbert, Monty, Eghosa, Osa, Karim, Muhammad, Williams, Lowri, Tucker, Louise, Downs, Tom, Walford, Rebecca, Hook, Annabelle, Mounce, Adam, Eccles, Emily, Edwards, Ross, Ramesh, Kirtika, Hall, Charlie, Lazarou, Maria, Jones, Rhidian, McGillian, Katy, Bhachoo, Hari Singh, The, Zoe, Inpahas, Vithusha, Desai, Ruchi, Cheema, Yusuf, Hughes, Andrew, Cranage, Olivia, Bee, Felicity, Osman, Khalid, Khan, Humza, Pitt, Jennifer, Pickwick, Charlotte, Carter, Jorge, Andrew, Fiona, Seedat, Naseera, Patel, Roshni, Walker, Megan, Boam, Alicia, Randall, Jessica, Bowyer, Beth, Edwards, Josh, Jones, Natasha, Walker, Emma, MacNaught, Ailsa, Balachandran, Swagath, Shipley, Abbie, Louise Kent, Jennifer, Tilley, Samuel, Davies, Bethany, Withers, Emma, Parmar, Krishna, Webber, Lucie, Sharma, Angelica, Handley, Amy, Gordon, Alexandra, Allen, Lucy, Paddock, Rebecca, Penney, Harriet, Banerjee, Lopa, Vanderpump, Chloe Victoria, Harding, Kate, Burke, John, Minik, Orsolya, Jarrett, Nia, Rowe, Ellie, Anomneze-Collins, Adanna, Griffiths, Harry, Pengelly, Sarah, Bennett, Ffion, Bilal, Ahmed, El-badawey, Abdullah, Ellis, Bethan, Cook, Luke, Elizabeth Valentine Maine, Harriet, Armstrong, Kiri, Beresford, Hannah, Raven-Gregg, Timia, Liddell-Lowe, Tom, Ong, Caitlin, Reed, Harriet, Alice St John, Frederika, Julia Kozuch, Weronika, Ray, Isabelle, Anuprabha Silva, Irukshi, Natalie Cheng, Sin Ting, Ali, Umme-Laila, Syed, Noreena, Murphy, Luke, Grother, Thomas, Smith, Harry, Watson, Rachel, Marei, Omar, Kirby, Emma, Gilfedder, Anna, Maw, Lydia, O’Connor, Sarah, Maden, Charlotte, Jones, Helena, Preston, Hazel, Binti Maliki, Nur Amirah, Zimmerman, Mark, Webber, Jessica, Jones, Llewelyn, Phillips, Rebecca, McCarthy, Lauren, Hubbard, Emily, Duffy, Leo, Guerrier Sadler, Abigail, Szakmany, Tamas, Richards, Owen, King, Charles, Killick, Charlotte, Chema, Yusuf, Shergill, Kavita, Huen, Yi, Lau, Lillian, Mustafa Ali, Hannah, Wilcock, Lucas, Timlin, Molly, Rela, Ayeesha, Smith, Daniel, Ireland, Sarah, Evans, Jennifer, Poobalan, Nayanatara, Pearce, Jessica, Vadiveloo, Thivya V, Black, Zoe, Samuel, Daniel Elis, Hussain, Humaira, Hawkins, Joanna, Atiyah, Zeid, Creamer, Rebecca, Zafar, Maham, Almazeedi, Ahmad, Brunnock, Hannah, Nasser, Zain, Jeyanthi, Mekha, Moghbel, Poorya, Kwan, Katie, Sutherland, Isobel, Davis, Frank, Rogers, Abigail, Tan, Zhao Xuan, Chantrill, Clare, Robertson, Amal, Foulkes, Jonathan, Khanam, Rahana, John, Jomcy, Meehan, Sarah Hannah, Metezai, Huria, Dawson, Hannah, Vadivale, Navrhinaa, Lee, Camilla, Dhadda, Amrit, Cleaver, Sian, Logue, Genna, Inns, Joy, Jones, Isabel, Howcroft, Robyn, Gilbert, Carys, Bradley, Matthew, Pike, Louise, Keeling, Rachel, Banks, Charldré, Cochrane, Eleanor, McFadyen, James, Mo, Matthew, Ireland, Emily, Brittain, Esme, Laid, Ihssen, Green, Charlotte, Mcforrester, Adriel, Michelle Ly, Xuong, Nalbanti, Mariana, Joseph, Raven, Tagg, Jack, Purchase, David, Myat, Pan, Niina, Ayako, Joshua Jones, Tyler, Hughes Thomas, Lowri, Hoyle, Natalie, Benc, Patrick, Davies, Ellen, Wu, Meng-Chieh, Fellows, David, Tilley, Sam, Baxendale, Eloise, Khan, Karishma, Forrester, Andrew, Moore, Oliver, Lim, Hse Juinn, Owen, Aimee, Hussain, Faris, Allybocus, Nima-banu, Sethi, Maneha, Waring, Harry, Khan, Adeel, Smith, Claire, Doyle, Nicholas, Yahya Amjad, Mohammad, Galloway, Luke, Morgan, Paul, Ellis, Gemma, Lundin, Robert, Al Hassan, Haamed, Markall, Bethan, Kaur, Namratha, Onyango, Emmanuel, Beard, Heather, Field, Elliot, Nelson-Rowe, Ellen, Adcock, Lizzie, Stoddart, Amelia, St John, Frederika, Sivananthan, Mathoorika, Jones, Rhys, Yeon Kwak, Sung, Farakish, Lily, Rhys-Ellis, Holly, Moss, Kate, Ray, Tallulah, David, Tessa, Roberts, Talea, Quy, Annie, Paranjape, Aniket, Bee, Felicity, Poolworaluk, Nutchanun, Keast, Mary, Yao, Si Liang, Manning, Dion, Irwin, Isobel, Asim, Umair, Boggon, Emelia, Alkurd, Ibrahim, Lawerece, Genevieve, Brown, Jade, Murphy, Emily, Lambert, Evie, Guilford, Jeremy, Payne, Beth, Almulaifi, Mariam, Poacher, Arwel, Ganesananthan, Sashiananthan, Cunningham-Walker, Berenice, Spooner, Chloe, Kiran, Akanksha, Nadeem, Nabeegh, Unadkat, Vidhi, Sparey, Esme, Li, David, Smith, Jessica, Corrin, India, Kurani, Amit, McNulty, Paul, Brown, Ceri, Groblewski, Wojciech, Szoke, Szilvia, Redman, Amelia, McKeag, Esther, Donnir, Anastasia, Ravishangar, Gaautham, Howard, Emanuela, Salmon, Charlotte, Tanatova, Sara, Kew, Jasmine, Clark, Megan Eilis, Hannay, Ellen, Godsafe, Olesya, Houghton, Christina, Lavric, Francesca, Mallinson, Rachel, Littler, Chris, Reddy, Harsha, Campbell, Andrew, Soo, Benedict, Evans, Rachel, Donowho, Georgina, Cawthra, Alexandra, Davies, Maddison, Lawrence Ashman, Matthew, Scriven, Jamie, Vautrey, James, Seet, Shannon, Britton, Imogen, Hodgson, Abigail, Twohey, Emma, Robbins, Joseph, Yung Ling, Vanessa Yeo, Asjadi, Kimiya, Yee Shean, Carven Chin, McCarroll, Zoe, Amatotsero, Oritseweyimi, Priscilla Chan, Hei Man, Cho Hui, John Ng, Ashaye, Antonia, Acheampong, Josephine, Adeleye, Ayowade, Ahmed, Saber, Chrysostomou, Alexandra, Unwin, Harry, Ang, Eshen, McSwiney, Niamh, Lim, Yin Yin, Lee, Zong Xuan, Kulikouskaya, Svetlana, Zulkifili, Nur, Lim, Sheryl, Xin, Lim, Urazbayeva, Adiya, Ahmad Hanif, Nur Haslina, Ying, Yau Ke, Coleclough, Alice, Higgins, Eilis, Spencer, Naomi, Ng, Tze Gee, Booth, Sam, Wai Yee Ng, Stephanie, Subbe, Christian P, Patterson, Isabella, Chia, Wen Li, Mukit, Abdullah, Vivian Pak, Hei Yi, Lock, Felicity, Nalmpanti, Mariana, Thomas, Shôn Alun, Burgher, Tanisha, Zhen Yeo, Alfred Wei, Powell Jones, Siwan, Miles, Charlie, Perry, Millicent, Burton, Holly, Powell, Katharine, Nessa, Luthfun, Fadlalla, Aalaa, Morgan, Rhian, Hodges, Elizabeth, Heal, Amelia, Scott, Chloe, Tayler, Alice, Chandy, Thomas, Taufik, Abduahad, Cochrane, James, Willis, Samuel, Heng, Sieh Yen, Cooper, Alex, von der Pahlen, Henrik Graf, Talbot, Isabella, Roberts, Robin Gwyn, Smith, Jessica Sharma, Sweeney, Aisling, Roberts, Cerian, Bausor, Laura, Chania, Thomas, Daniah, Puw, Elen Wyn, Lyons, Ronan A, Hall, Judith E
Publicado 2021