Genetic Code Expansion: A Powerful Tool for Understanding the Physiological Consequences of Oxidative Stress Protein Modifications

por Porter, Joseph J., Mehl, Ryan A.
Publicado 2018

Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli

por Zhu, Phillip, Mehl, Ryan A., Cooley, Richard B.
Publicado 2023

Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences

por Petersson, E. James, Mehl, Ryan A., Ahern, Christopher A.
Publicado 2019

Chemically-defined lactose-based autoinduction medium for site-specific incorporation of non-canonical amino acids into proteins

por Muzika, Michael, Muskat, Natali H., Sarid, Shani, Ben-David, Oshrit, Mehl, Ryan A., Arbely, Eyal
Publicado 2018

Characterization of the Lipid Binding Properties of Otoferlin Reveals Specific Interactions between PI(4,5)P2 and the C2C and C2F Domains

por Padmanarayana, Murugesh, Hams, Nicole, Speight, Lee C., Petersson, E. James, Mehl, Ryan A., Johnson, Colin P.
Publicado 2014

Accessing isotopically labeled proteins containing genetically encoded phosphoserine for NMR with optimized expression conditions

por Vesely, Cat Hoang, Reardon, Patrick N., Yu, Zhen, Barbar, Elisar, Mehl, Ryan A., Cooley, Richard B.
Publicado 2022

Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP

por Chatterjee, Debashree, Cooley, Richard B, Boyd, Chelsea D, Mehl, Ryan A, O'Toole, George A, Sondermann, Holger
Publicado 2014

Nanobody assemblies with fully flexible topology enabled by genetically encoded tetrazine amino acids

por Van Fossen, Elise M., Bednar, Riley M., Jana, Subhashis, Franklin, Rachel, Beckman, Joseph, Karplus, P. Andrew, Mehl, Ryan A.
Publicado 2022

High‐yield recombinant bacterial expression of (13)C‐, (15)N‐labeled, serine‐16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protoco...

por Buchko, Garry W., Zhou, Mowei, Vesely, Cat Hoang, Tao, Jinhui, Shaw, Wendy J., Mehl, Ryan A., Cooley, Richard B.
Publicado 2023

Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues

por Taylor, Christopher J., Hardy, Florence J., Burke, Ashleigh J., Bednar, Riley M., Mehl, Ryan A., Green, Anthony P., Lovelock, Sarah L.
Publicado 2023

Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases

por Cooley, Richard B., Feldman, Jessica L., Driggers, Camden M., Bundy, Taylor A., Stokes, Audrey L., Karplus, P. Andrew, Mehl, Ryan A.
Publicado 2014

Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

por Pokhrel, Nilisha, Origanti, Sofia, Davenport, Eric Parker, Gandhi, Disha, Kaniecki, Kyle, Mehl, Ryan A., Greene, Eric C., Dockendorff, Chris, Antony, Edwin
Publicado 2017

Increasing Enzyme Stability and Activity through Hydrogen Bond-Enhanced Halogen Bonds

por Carlsson, Anna-Carin C., Scholfield, Matthew R., Rowe, Rhianon K., Ford, Melissa Coates, Alexander, Austin T., Mehl, Ryan A., Ho, P. Shing
Publicado 2018

Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling

por Lambert, William D., Scinto, Samuel L., Dmitrenko, Olga, Boyd, Samantha J., Magboo, Ronald, Mehl, Ryan A., Chin, Jason W., Fox, Joseph M., Wallace, Stephen
Publicado 2017

PermaPhos(Ser): autonomous synthesis of functional, permanently phosphorylated proteins

por Zhu, Phillip, Franklin, Rachel, Vogel, Amber, Stanisheuski, Stanislau, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Publicado 2021

Correction: Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling

por Lambert, William D., Scinto, Samuel L., Dmitrenko, Olga, Boyd, Samantha J., Magboo, Ronald, Mehl, Ryan A., Chin, Jason W., Fox, Joseph M., Wallace, Stephen
Publicado 2017

Dissecting Optical Response and Molecular Structure of Fluorescent Proteins With Non-canonical Chromophores

por Oscar, Breland G., Zhu, Liangdong, Wolfendeen, Hayati, Rozanov, Nikita D., Chang, Alvin, Stout, Kenneth T., Sandwisch, Jason W., Porter, Joseph J., Mehl, Ryan A., Fang, Chong
Publicado 2020

Creating a Selective Nanobody Against 3-Nitrotyrosine Containing Proteins

por Van Fossen, Elise M., Grutzius, Sonia, Ruby, Carl E., Mourich, Dan V., Cebra, Chris, Bracha, Shay, Karplus, P. Andrew, Cooley, Richard B., Mehl, Ryan A.
Publicado 2022

Ultra-Fast Bioorthogonal Spin-Labeling and Distance Measurements in Mammalian Cells Using Small, Genetically Encoded Tetrazine Amino Acids

por Jana, Subhashis, Evans, Eric G. B., Jang, Hyo Sang, Zhang, Shuyang, Zhang, Hui, Rajca, Andrzej, Gordon, Sharona E., Zagotta, William N., Stoll, Stefan, Mehl, Ryan A.
Publicado 2023

Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ

por Zhu, Phillip, Stanisheuski, Stanislau, Franklin, Rachel, Vogel, Amber, Vesely, Cat Hoang, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Publicado 2023