MITOCHONDRIAL-DERIVED PEPTIDE, SHLP2, A NOVEL PROTECTIVE FACTOR IN PARKINSON’S DISEASE

por Kim, Su Jeong, Devgan, Anjali, Mehta, Hemal H, Cohen, Pinchas
Publicado 2019

MITOCHONDRIAL DNA VARIANT C2639T IS AN APOE4 RESILIENCE FACTOR

por Miller, Brendan, Kim, Su Jeong, Wan, Junxiang, Mehta, Hemal H, Yen, Kelvin, Cohen, Pinchas
Publicado 2019

The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus

por Kim, Su-Jeong, Guerrero, Noel, Wassef, Gabriella, Xiao, Jialin, Mehta, Hemal H., Cohen, Pinchas, Yen, Kelvin
Publicado 2016

Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment

por Mehta, Hemal H., Xiao, Jialin, Ramirez, Ricardo, Miller, Brendan, Kim, Su-Jeong, Cohen, Pinchas, Yen, Kelvin
Publicado 2019

Mito-Omics and immune function: Applying novel mitochondrial omic techniques to the context of the aging immune system

por Silverstein, Ana R., Flores, Melanie K., Miller, Brendan, Kim, Su-Jeong, Yen, Kelvin, Mehta, Hemal H., Cohen, Pinchas
Publicado 2020

The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity

por Kim, Su‐Jeong, Miller, Brendan, Mehta, Hemal H., Xiao, Jialin, Wan, Junxiang, Arpawong, Thalida E., Yen, Kelvin, Cohen, Pinchas
Publicado 2019

Mitochondrial peptides modulate mitochondrial function during cellular senescence

por Kim, Su-Jeong, Mehta, Hemal H., Wan, Junxiang, Kuehnemann, Chisaka, Chen, Jingcheng, Hu, Ji-Fan, Hoffman, Andrew R., Cohen, Pinchas
Publicado 2018

Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples

por Miller, Brendan, Silverstein, Ana, Flores, Melanie, Cao, Kevin, Kumagai, Hiroshi, Mehta, Hemal H., Yen, Kelvin, Kim, Su- Jeong, Cohen, Pinchas
Publicado 2021

The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction

por Sreekumar, Parameswaran G., Ishikawa, Keijiro, Spee, Chris, Mehta, Hemal H., Wan, Junxiang, Yen, Kelvin, Cohen, Pinchas, Kannan, Ram, Hinton, David R.
Publicado 2016

Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies

por Miller, Brendan, Arpawong, Thalida E., Jiao, Henry, Kim, Su-Jeong, Yen, Kelvin, Mehta, Hemal H., Wan, Junxiang, Carpten, John C., Cohen, Pinchas
Publicado 2019

A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population

por Miller, Brendan, Torres, Mina, Jiang, Xuejuan, McKean-Cowdin, Roberta, Nousome, Darryl, Kim, Su-Jeong, Mehta, Hemal H., Yen, Kelvin, Cohen, Pinchas, Varma, Rohit
Publicado 2020

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

por Cobb, Laura J., Lee, Changhan, Xiao, Jialin, Yen, Kelvin, Wong, Richard G., Nakamura, Hiromi K., Mehta, Hemal H., Gao, Qinglei, Ashur, Carmel, Huffman, Derek M., Wan, Junxiang, Muzumdar, Radhika, Barzilai, Nir, Cohen, Pinchas
Publicado 2016

Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time

por Xu, Tong, Junge, Jason A., Delfarah, Alireza, Lu, Yi-Tsung, Arnesano, Cosimo, Iqbal, Maheen, Delijani, Kevin, Hsieh, Tien-Chan, Hodara, Emmanuelle, Mehta, Hemal H., Cohen, Pinchas, Graham, Nicholas A., Fraser, Scott E., Goldkorn, Amir
Publicado 2022

Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans

por Yen, Kelvin, Wan, Junxiang, Mehta, Hemal H., Miller, Brendan, Christensen, Amy, Levine, Morgan E., Salomon, Matthew P., Brandhorst, Sebastian, Xiao, Jialin, Kim, Su-Jeong, Navarrete, Gerardo, Campo, Daniel, Harry, G. Jean, Longo, Valter, Pike, Christian J., Mack, Wendy J., Hodis, Howard N., Crimmins, Eileen M., Cohen, Pinchas
Publicado 2018

The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan

por Yen, Kelvin, Mehta, Hemal H., Kim, Su-Jeong, Lue, YanHe, Hoang, James, Guerrero, Noel, Port, Jenna, Bi, Qiuli, Navarrete, Gerardo, Brandhorst, Sebastian, Lewis, Kaitlyn Noel, Wan, Junxiang, Swerdloff, Ronald, Mattison, Julie A., Buffenstein, Rochelle, Breton, Carrie V., Wang, Christina, Longo, Valter, Atzmon, Gil, Wallace, Douglas, Barzilai, Nir, Cohen, Pinchas
Publicado 2020

A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c

por Zempo, Hirofumi, Kim, Su-Jeong, Fuku, Noriyuki, Nishida, Yuichiro, Higaki, Yasuki, Wan, Junxiang, Yen, Kelvin, Miller, Brendan, Vicinanza, Roberto, Miyamoto-Mikami, Eri, Kumagai, Hiroshi, Naito, Hisashi, Xiao, Jialin, Mehta, Hemal H., Lee, Changhan, Hara, Megumi, Patel, Yesha M., Setiawan, Veronica W., Moore, Timothy M., Hevener, Andrea L., Sutoh, Yoichi, Shimizu, Atsushi, Kojima, Kaname, Kinoshita, Kengo, Arai, Yasumichi, Hirose, Nobuyoshi, Maeda, Seiji, Tanaka, Keitaro, Cohen, Pinchas
Publicado 2021