Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer’s Disease

por Meier, Silvio R., Sehlin, Dag, Hultqvist, Greta, Syvänen, Stina
Publicado 2021

Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β

por Sehlin, Dag, Fang, Xiaotian T., Meier, Silvio R., Jansson, Malin, Syvänen, Stina
Publicado 2017

Antibody-Based In Vivo PET Imaging Detects Amyloid-β Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition

por Meier, Silvio R., Syvänen, Stina, Hultqvist, Greta, Fang, Xiaotian T., Roshanbin, Sahar, Lannfelt, Lars, Neumann, Ulf, Sehlin, Dag
Publicado 2018

A Brain-Targeting Bispecific-Multivalent Antibody Clears Soluble Amyloid-Beta Aggregates in Alzheimer’s Disease Mice

por Rofo, Fadi, Meier, Silvio R., Metzendorf, Nicole G., Morrison, Jamie I., Petrovic, Alex, Syvänen, Stina, Sehlin, Dag, Hultqvist, Greta
Publicado 2022

(11)C-PiB and (124)I-Antibody PET Provide Differing Estimates of Brain Amyloid-β After Therapeutic Intervention

por Meier, Silvio R., Sehlin, Dag, Roshanbin, Sahar, Falk, Victoria Lim, Saito, Takashi, Saido, Takaomi C., Neumann, Ulf, Rokka, Johanna, Eriksson, Jonas, Syvänen, Stina
Publicado 2022

PET Imaging in Preclinical Anti-Aβ Drug Development

por Syvänen, Stina, Meier, Silvio R., Roshanbin, Sahar, Xiong, Mengfei, Faresjö, Rebecca, Gustavsson, Tobias, Bonvicini, Gillian, Schlein, Eva, Aguilar, Ximena, Julku, Ulrika, Eriksson, Jonas, Sehlin, Dag
Publicado 2022