ETMM-05. LACTIC ACID FACILITATES GLIOBLASTOMA GROWTH THROUGH MODULATION OF THE EPIGENOME

por Torrini, Consuelo, Nguyen, Trang, Shu, Chang, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Karpel-Massler, Georg, Bruce, Jeffrey, Canoll, Peter, Siegelin, Markus
Publicado 2021

Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm

por Ding, Hongxu, Douglass, Eugene F., Sonabend, Adam M., Mela, Angeliki, Bose, Sayantan, Gonzalez, Christian, Canoll, Peter D., Sims, Peter A., Alvarez, Mariano J., Califano, Andrea
Publicado 2018

Single-cell analysis of 5-aminolevulinic acid intraoperative labeling specificity for glioblastoma

por Liu, Zhouzerui, Mela, Angeliki, Argenziano, Michael G., Banu, Matei A., Furnari, Julia, Kotidis, Corina, Sperring, Colin P., Humala, Nelson, Mahajan, Aayushi, Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Publicado 2023

ETMM-04. AURKA INHIBITION REPROGRAMS METABOLISM AND IS SYNTHETICALLY LETHAL WITH FATTY ACID OXIDATION INHIBITION IN GLIOBLASTOMA MODEL SYSTEMS

por Nguyen, Trang, Shu, Chang, Shang, Enyuan, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Akman, Hasan, Quinzii, Catarina, Zhang, Guoan, Westhof, Mike-Andrew, Karpel-Massler, Georg, Bruce, Jeffrey, Canoll, Peter, Siegelin, Markus
Publicado 2021

PRMT5-mediated regulation of developmental myelination

por Scaglione, Antonella, Patzig, Julia, Liang, Jialiang, Frawley, Rebecca, Bok, Jabez, Mela, Angeliki, Yattah, Camila, Zhang, Jingxian, Teo, Shun Xie, Zhou, Ting, Chen, Shuibing, Bernstein, Emily, Canoll, Peter, Guccione, Ernesto, Casaccia, Patrizia
Publicado 2018

Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons

por Genestine, Matthieu, Ambriz, Daisy, Crabtree, Gregg W, Dummer, Patrick, Molotkova, Anna, Quintero, Michael, Mela, Angeliki, Biswas, Saptarshi, Feng, Huijuan, Zhang, Chaolin, Canoll, Peter, Hargus, Gunnar, Agalliu, Dritan, Gogos, Joseph A, Au, Edmund
Publicado 2021

Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition

por Roupakia, Eugenia, Chavdoula, Evangelia, Karpathiou, Georgia, Vatsellas, Giannis, Chatzopoulos, Dimitrios, Mela, Angeliki, Gillette, Jennifer M., Kriegsmann, Katharina, Kriegsmann, Mark, Batistatou, Anna, Goussia, Anna, Marcu, Kenneth B., Karteris, Emmanouil, Klinakis, Apostolos, Kolettas, Evangelos
Publicado 2021

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

por Nguyen, Trang T. T., Shang, Enyuan, Shu, Chang, Kim, Sungsoo, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Yang, Hee Won, Akman, Hasan Orhan, Quinzii, Catarina M., Zhang, Guoan, Westhoff, Mike-Andrew, Karpel-Massler, Georg, Bruce, Jeffrey N., Canoll, Peter, Siegelin, Markus D.
Publicado 2021

Glioma-Induced Alterations in Neuronal Activity and Neurovascular Coupling during Disease Progression

por Montgomery, Mary Katherine, Kim, Sharon H., Dovas, Athanassios, Zhao, Hanzhi T., Goldberg, Alexander R., Xu, Weihao, Yagielski, Alexis J., Cambareri, Morgan K., Patel, Kripa B., Mela, Angeliki, Humala, Nelson, Thibodeaux, David N., Shaik, Mohammed A., Ma, Ying, Grinband, Jack, Chow, Daniel S., Schevon, Catherine, Canoll, Peter, Hillman, Elizabeth M.C.
Publicado 2020

Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer

por Biswas, Anup Kumar, Han, Seoyoung, Tai, Yifan, Ma, Wanchao, Coker, Courtney, Quinn, S. Aidan, Shakri, Ahmad Rushdi, Zhong, Timothy James, Scholze, Hanna, Lagos, Galina G., Mela, Angeliki, Manova-Todorova, Katia, de Stanchina, Elisa, Ferrando, Adolfo A., Mendelsohn, Cathy, Canoll, Peter, Yu, Helena A., Paik, Paul K., Saqi, Anjali, Shu, Catherine A., Kris, Mark G., Massague, Joan, Acharyya, Swarnali
Publicado 2022

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

por Upadhyayula, Pavan S., Higgins, Dominique M., Mela, Angeliki, Banu, Matei, Dovas, Athanassios, Zandkarimi, Fereshteh, Patel, Purvi, Mahajan, Aayushi, Humala, Nelson, Nguyen, Trang T. T., Chaudhary, Kunal R., Liao, Lillian, Argenziano, Michael, Sudhakar, Tejaswi, Sperring, Colin P., Shapiro, Benjamin L., Ahmed, Eman R., Kinslow, Connor, Ye, Ling F., Siegelin, Markus D., Cheng, Simon, Soni, Rajesh, Bruce, Jeffrey N., Stockwell, Brent R., Canoll, Peter
Publicado 2023