Functional Variation in the FAAH Gene Is Directly Associated with Subjective Well-Being and Indirectly Associated with Problematic Alcohol Use

por Bornscheuer, Lisa, Lundin, Andreas, Forsell, Yvonne, Lavebratt, Catharina, Melas, Philippe A.
Publicado 2023

Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research

por Melas, Philippe A., Scherma, Maria, Fratta, Walter, Cifani, Carlo, Fadda, Paola
Publicado 2021

The cannabinoid receptor-1 gene interacts with stressful life events to increase the risk for problematic alcohol use

por Bornscheuer, Lisa, Lundin, Andreas, Forsell, Yvonne, Lavebratt, Catharina, Melas, Philippe A.
Publicado 2022

Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene

por Wei, Ya Bin, Melas, Philippe A., Wegener, Gregers, Mathé, Aleksander A., Lavebratt, Catharina
Publicado 2015

The monoamine stabilizer OSU6162 has anxiolytic-like properties and reduces voluntary alcohol intake in a genetic rat model of depression

por Melas, Philippe A., Wirf, Malin, André, Helder, Jayaram-Lindström, Nitya, Mathé, Aleksander A., Steensland, Pia
Publicado 2021

Physical exercise is associated with a reduction in plasma levels of fractalkine, TGF-β1, eotaxin-1 and IL-6 in younger adults with mobility disability

por Kumar, Parvin, Stiernborg, Miranda, Fogdell-Hahn, Anna, Månsson, Kristoffer, Furmark, Tomas, Berglind, Daniel, Melas, Philippe A., Forsell, Yvonne, Lavebratt, Catharina
Publicado 2022

Synaptoproteomic Analysis of the Prefrontal Cortex Reveals Spatio-Temporal Changes in SYNGAP1 Following Cannabinoid Exposure in Rat Adolescence

por Qvist, Johanna S., Scherma, Maria, Jayaram-Lindström, Nitya, Fratta, Walter, Kandel, Denise B., Kandel, Eric R., Fadda, Paola, Melas, Philippe A.
Publicado 2022

Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood

por Kononoff, Jenni, Melas, Philippe A., Kallupi, Marsida, de Guglielmo, Giordano, Kimbrough, Adam, Scherma, Maria, Fadda, Paola, Kandel, Denise B., Kandel, Eric R., George, Olivier
Publicado 2018

NR3C1 hypermethylation in depressed and bullied adolescents

por Efstathopoulos, Paschalis, Andersson, Filip, Melas, Philippe A., Yang, Liu L., Villaescusa, J. Carlos, Rȕegg, Joëlle, Ekström, Tomas J., Forsell, Yvonne, Galanti, Maria Rosaria, Lavebratt, Catharina
Publicado 2018

Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5

por Griffin, Edmund A., Melas, Philippe A., Zhou, Royce, Li, Yang, Mercado, Peter, Kempadoo, Kimberly A., Stephenson, Stacy, Colnaghi, Luca, Taylor, Kathleen, Hu, Mei-Chen, Kandel, Eric R., Kandel, Denise B.
Publicado 2017

MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro

por Wei, Ya Bin, Melas, Philippe A., Villaescusa, J. Carlos, Liu, Jia Jia, Xu, Ning, Christiansen, Søren Hofman, Elbrønd-Bek, Heidi, Woldbye, David Paul Drucker, Wegener, Gregers, Mathé, Aleksander A., Lavebratt, Catharina
Publicado 2016

Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine

por Scherma, Maria, Qvist, Johanna S., Asok, Arun, Huang, Shao-shan C., Masia, Paolo, Deidda, Matteo, Wei, Ya B., Soni, Rajesh K., Fratta, Walter, Fadda, Paola, Kandel, Eric R., Kandel, Denise B., Melas, Philippe A.
Publicado 2020