Oncolytic Virus Immunotherapy

por Marchini, Antonio, Ilkow, Carolina S., Melcher, Alan
Publicado 2021

Radiotherapy enhances responses of lung cancer to CTLA-4 blockade

por Wilkins, Anna, McDonald, Fiona, Harrington, Kevin, Melcher, Alan
Publicado 2019

The Hitchhiker's Guide to Virotherapy

por Donnelly, Oliver, Vile, Richard, Pandha, Hardev, Harrington, Kevin, Melcher, Alan
Publicado 2012

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study

por Punta, Marco, Jennings, Victoria A., Melcher, Alan A., Lise, Stefano
Publicado 2020

Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances

por Simpson, Guy R, Relph, Kate, Harrington, Kevin, Melcher, Alan, Pandha, Hardev
Publicado 2016

Combination strategies incorporating oncolytic viruses and immune checkpoint inhibitors for advanced melanoma: what is the evidence?

por Wongariyapak, Amarin, Roulstone, Victoria, Melcher, Alan A., Pedersen, Malin, Harrington, Kevin J.
Publicado 2023

Phase I/II storm study: Intravenous delivery of a novel oncolytic immunotherapy agent, Coxsackievirus A21, in advanced cancer patients

por Pandha, Hardev, Harrington, Kevin, Ralph, Christy, Melcher, Alan, Grose, Mark, Shafren, Darren
Publicado 2015

Breaking the barriers in cancer care: The next generation of herpes simplex virus-based oncolytic immunotherapies for cancer treatment

por Khushalani, Nikhil I., Harrington, Kevin J., Melcher, Alan, Bommareddy, Praveen K., Zamarin, Dmitriy
Publicado 2023

Differential effects of Paclitaxel on dendritic cell function

por John, Justin, Ismail, Mohammed, Riley, Catherine, Askham, Jonathan, Morgan, Richard, Melcher, Alan, Pandha, Hardev
Publicado 2010

Oncolytic Viruses: Do They Have a Role in Anti-Cancer Therapy?

por Prestwich, Robin J, Errington, Fiona, Harrington, Kevin J., Pandha, Hardev S., Selby, Peter, Melcher, Alan
Publicado 2008

Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going?

por Turnbull, Samantha, West, Emma J., Scott, Karen J., Appleton, Elizabeth, Melcher, Alan, Ralph, Christy
Publicado 2015

Applications of coxsackievirus A21 in oncology

por Bradley, Stephen, Jakes, Adam D, Harrington, Kevin, Pandha, Hardev, Melcher, Alan, Errington-Mais, Fiona
Publicado 2014

Single-Cycle Viral Gene Expression, Rather Than Progressive Replication and Oncolysis, Is Required for VSV Therapy of B16 Melanoma

por Galivo, Feorillo, Diaz, Rosa Maria, Wongthida, Phonphimon, Thompson, Jill, Kottke, Timothy, Barber, Glen, Melcher, Alan, Vile, Richard
Publicado 2009

Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

por Chan Wah Hak, Charleen M. L., Rullan, Antonio, Patin, Emmanuel C., Pedersen, Malin, Melcher, Alan A., Harrington, Kevin J.
Publicado 2022

Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming

por Steele, Lynette, Errington, Fiona, Prestwich, Robin, Ilett, Elizabeth, Harrington, Kevin, Pandha, Hardev, Coffey, Matt, Selby, Peter, Vile, Richard, Melcher, Alan
Publicado 2011

Oncolytic Reovirus-Mediated Recruitment of Early Innate Immune Responses Reverses Immunotherapy Resistance in Prostate Tumors

por Annels, Nicola E., Simpson, Guy R., Denyer, Mick, Arif, Mehreen, Coffey, Matt, Melcher, Alan, Harrington, Kevin, Vile, Richard, Pandha, Hardev
Publicado 2020

Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma

por McKelvey, Kelly J., Wilson, Erica B., Short, Susan, Melcher, Alan A., Biggs, Michael, Diakos, Connie I., Howell, Viive M.
Publicado 2021

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

por Wilson, Erica B., El-Jawhari, Jehan J., Neilson, Abbie L., Hall, Geoffrey D., Melcher, Alan A., Meade, Josephine L., Cook, Graham P.
Publicado 2011

A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patients

por Sadanandam, Anguraj, Bopp, Tobias, Dixit, Santosh, Knapp, David J. H. F., Emperumal, Chitra Priya, Vergidis, Paschalis, Rajalingam, Krishnaraj, Melcher, Alan, Kannan, Nagarajan
Publicado 2020

Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model

por Andreou, Tereza, Williams, Jennifer, Brownlie, Rebecca J, Salmond, Robert J, Watson, Erica, Shaw, Gary, Melcher, Alan, Wurdak, Heiko, Short, Susan C, Lorger, Mihaela
Publicado 2021