Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

por Meleddu, Rita, Distinto, Simona, Corona, Angela, Tramontano, Enzo, Bianco, Giulia, Melis, Claudia, Cottiglia, Filippo, Maccioni, Elias
Publicado 2016

5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

por Corona, Angela, Meleddu, Rita, Delelis, Olivier, Subra, Frederic, Cottiglia, Filippo, Esposito, Francesca, Distinto, Simona, Maccioni, Elias, Tramontano, Enzo
Publicado 2023

Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor

por Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Maccioni, Elias, Le Grice, Stuart SF, Tramontano, Enzo
Publicado 2013

Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H funct...

por Fois, Benedetta, Corona, Angela, Tramontano, Enzo, Distinto, Simona, Maccioni, Elias, Meleddu, Rita, Caboni, Pierluigi, Floris, Costantino, Cottiglia, Filippo
Publicado 2021

Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

por Melis, Claudia, Meleddu, Rita, Angeli, Andrea, Distinto, Simona, Bianco, Giulia, Capasso, Clemente, Cottiglia, Filippo, Angius, Rossella, Supuran, Claudiu T., Maccioni, Elias
Publicado 2016

Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B

por Meleddu, Rita, Distinto, Simona, Cirilli, Roberto, Alcaro, Stefano, Yanez, Matilde, Sanna, Maria Luisa, Corona, Angela, Melis, Claudia, Bianco, Giulia, Matyus, Peter, Cottiglia, Filippo, Maccioni, Elias
Publicado 2017

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

por Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Masaoka, Takashi, Maccioni, Elias, Menéndez-Arias, Luis, Alcaro, Stefano, Le Grice, Stuart F. J., Tramontano, Enzo
Publicado 2016

Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

por Fois, Benedetta, Distinto, Simona, Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Floris, Costantino, Rosa, Antonella, Nieddu, Mariella, Caboni, Pierluigi, Sissi, Claudia, Angeli, Andrea, Supuran, Claudiu T., Cottiglia, Filippo
Publicado 2020

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

por Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Ortuso, Francesco, Cottiglia, Filippo, Secci, Daniela, Onali, Alessia, Sanna, Erica, Angeli, Andrea, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Distinto, Simona
Publicado 2021

Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases

por Distinto, Simona, Meleddu, Rita, Ortuso, Francesco, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Melis, Claudia, Fois, Benedetta, Angeli, Andrea, Capasso, Clemente, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Maccioni, Elias
Publicado 2019

N-Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms

por Bianco, Giulia, Meleddu, Rita, Distinto, Simona, Cottiglia, Filippo, Gaspari, Marco, Melis, Claudia, Corona, Angela, Angius, Rossella, Angeli, Andrea, Taverna, Domenico, Alcaro, Stefano, Leitans, Janis, Kazaks, Andris, Tars, Kaspars, Supuran, Claudiu T., Maccioni, Elias
Publicado 2017

Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

por Meleddu, Rita, Corona, Angela, Distinto, Simona, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Secci, Daniela, Onali, Alessia, Sanna, Erica, Esposito, Francesca, Cirone, Italo, Ortuso, Francesco, Alcaro, Stefano, Tramontano, Enzo, Mátyus, Péter, Maccioni, Elias
Publicado 2021