Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

por Tynell, Janne, Melén, Krister, Julkunen, Ilkka
Publicado 2014

Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin

por Melén, Krister, Tynell, Janne, Fagerlund, Riku, Roussel, Pascal, Hernandez-Verdun, Danièle, Julkunen, Ilkka
Publicado 2012

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression

por Kaukinen, Pasi, Sillanpää, Maarit, Kotenko, Sergei, Lin, Rongtuan, Hiscott, John, Melén, Krister, Julkunen, Ilkka
Publicado 2006

Hepatitis C virus core, NS3, NS4B and NS5A are the major immunogenic proteins in humoral immunity in chronic HCV infection

por Sillanpää, Maarit, Melén, Krister, Porkka, Päivi, Fagerlund, Riku, Nevalainen, Kaisu, Lappalainen, Maija, Julkunen, Ilkka
Publicado 2009

SARS-CoV-2 Isolates Show Impaired Replication in Human Immune Cells but Differential Ability to Replicate and Induce Innate Immunity in Lung Epithelial Cells

por Jiang, Miao, Kolehmainen, Pekka, Kakkola, Laura, Maljanen, Sari, Melén, Krister, Smura, Teemu, Julkunen, Ilkka, Österlund, Pamela
Publicado 2021

Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

por Lundberg, Rickard, Melén, Krister, Westenius, Veera, Jiang, Miao, Österlund, Pamela, Khan, Hira, Vapalahti, Olli, Julkunen, Ilkka, Kakkola, Laura
Publicado 2019

Blood MxA protein as a marker for respiratory virus infections in young children

por Toivonen, Laura, Schuez-Havupalo, Linnea, Rulli, Maris, Ilonen, Jorma, Pelkonen, Jukka, Melen, Krister, Julkunen, Ilkka, Peltola, Ville, Waris, Matti
Publicado 2015

Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation

por He, Felix B., Khan, Hira, Huttunen, Moona, Kolehmainen, Pekka, Melén, Krister, Maljanen, Sari, Qu, Mengmeng, Jiang, Miao, Kakkola, Laura, Julkunen, Ilkka
Publicado 2022

No evidence of autoimmunity to human OX(1) or OX(2) orexin receptors in Pandemrix-vaccinated narcoleptic children

por Melén, Krister, Jalkanen, Pinja, Kukkonen, Jyrki P., Partinen, Markku, Nohynek, Hanna, Vuorela, Arja, Vaarala, Outi, Freitag, Tobias L., Meri, Seppo, Julkunen, Ilkka
Publicado 2020

Asian and African lineage Zika viruses show differential replication and innate immune responses in human dendritic cells and macrophages

por Österlund, Pamela, Jiang, Miao, Westenius, Veera, Kuivanen, Suvi, Järvi, Riia, Kakkola, Laura, Lundberg, Rickard, Melén, Krister, Korva, Miša, Avšič – Županc, Tatjana, Vapalahti, Olli, Julkunen, Ilkka
Publicado 2019

No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix Vaccination Campaign in Finland

por Melén, Krister, Partinen, Markku, Tynell, Janne, Sillanpää, Maarit, Himanen, Sari-Leena, Saarenpää-Heikkilä, Outi, Hublin, Christer, Olsen, Päivi, Ilonen, Jorma, Nohynek, Hanna, Syrjänen, Ritva, Kilpi, Terhi, Vuorela, Arja, Kirjavainen, Turkka, Vaarala, Outi, Julkunen, Ilkka
Publicado 2013

A Combination of N and S Antigens With IgA and IgG Measurement Strengthens the Accuracy of SARS-CoV-2 Serodiagnostics

por Jalkanen, Pinja, Pasternack, Arja, Maljanen, Sari, Melén, Krister, Kolehmainen, Pekka, Huttunen, Moona, Lundberg, Rickard, Tripathi, Lav, Khan, Hira, Ritvos, Mikael A, Naves, Rauno, Haveri, Anu, Österlund, Pamela, Kuivanen, Suvi, Jääskeläinen, Anne J, Kurkela, Satu, Lappalainen, Maija, Rantasärkkä, Kaisa, Vuorinen, Tytti, Hytönen, Jukka, Waris, Matti, Tauriainen, Sisko, Ritvos, Olli, Kakkola, Laura, Julkunen, Ilkka
Publicado 2021