Comparative analysis of PD‐1 target engagement of dostarlimab and pembrolizumab in advanced solid tumors using ex vivo IL‐2 stimulation data

por Austin, Daren, Melhem, Murad, Gandhi, Yash, Lu, Sharon, Visser, Sandra
Publicado 2022

Bridging adults and paediatrics with secondary hyperparathyroidism receiving haemodialysis: a pharmacokinetic‐pharmacodynamic analysis of cinacalcet

por Chen, Ping, Sohn, Winnie, Narayanan, Adimoolam, Gisleskog, Per Olsson, Melhem, Murad
Publicado 2019

Population pharmacokinetics and exposure–response of anti‐programmed cell death protein‐1 monoclonal antibody dostarlimab in advanced solid tumours

por Melhem, Murad, Hanze, Eva, Lu, Sharon, Alskär, Oskar, Visser, Sandra, Gandhi, Yash
Publicado 2022

Receiver Operating Characteristic Analysis and Clinical Trial Simulation to Inform Dose Titration Decisions

por Clements, John David, Perez Ruixo, Juan Jose, Gibbs, John P., Doshi, Sameer, Perez Ruixo, Carlos, Melhem, Murad
Publicado 2018

Prediction of Survival Benefit of Filgrastim in Adult and Pediatric Patients With Acute Radiation Syndrome

por Harrold, John, Gisleskog, Per Olsson, Perez‐Ruixo, Juan Jose, Delor, Isabelle, Chow, Andrew, Jacqmin, Philippe, Melhem, Murad
Publicado 2020

Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF

por Harrold, John, Gisleskog, Per Olsson, Delor, Isabelle, Jacqmin, Philippe, Perez-Ruixo, Juan Jose, Narayanan, Adimoolam, Doshi, Sameer, Chow, Andrew, Yang, Bing-Bing, Melhem, Murad
Publicado 2020