A possible role for VPS13-family proteins in bulk lipid transfer, membrane expansion and organelle biogenesis

por Melia, Thomas J., Reinisch, Karin M.
Publicado 2022

Autophagosome biogenesis: From membrane growth to closure

por Melia, Thomas J., Lystad, Alf H., Simonsen, Anne
Publicado 2020

“VTT”-Domain Proteins VMP1 and TMEM41B Function in Lipid Homeostasis Globally and Locally as ER Scramblases

por Reinisch, Karin M., Chen, Xiao-Wei, Melia, Thomas J.
Publicado 2021

A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis

por Ghanbarpour, Alireza, Valverde, Diana P., Melia, Thomas J., Reinisch, Karin M.
Publicado 2021

Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex

por Shi, Lei, Kümmel, Daniel, Coleman, Jeff, Melia, Thomas J., Giraudo, Claudio G.
Publicado 2011

Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation

por Hong, Zhouping, Adlakha, Jyoti, Wan, Neng, Guinn, Emily, Giska, Fabian, Gupta, Kallol, Melia, Thomas J., Reinisch, Karin M.
Publicado 2022

Close Is Not Enough: Snare-Dependent Membrane Fusion Requires an Active Mechanism That Transduces Force to Membrane Anchors

por McNew, James A., Weber, Thomas, Parlati, Francesco, Johnston, Robert J., Melia, Thomas J., Söllner, Thomas H., Rothman, James E.
Publicado 2000

ATG2 transports lipids to promote autophagosome biogenesis

por Valverde, Diana P., Yu, Shenliang, Boggavarapu, Venkata, Kumar, Nikit, Lees, Joshua A., Walz, Thomas, Reinisch, Karin M., Melia, Thomas J.
Publicado 2019

Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome

por Chandra, Sunandini, Mannino, Philip J., Thaller, David J., Ader, Nicholas R., King, Megan C., Melia, Thomas J., Lusk, C. Patrick
Publicado 2021

SNAREs can promote complete fusion and hemifusion as alternative outcomes

por Giraudo, Claudio G., Hu, Chuan, You, Daoqi, Slovic, Avram M., Mosharov, Eugene V., Sulzer, David, Melia, Thomas J., Rothman, James E.
Publicado 2005

Lipidation of the LC3/GABARAP family of autophagy proteins relies upon a membrane curvature-sensing domain in Atg3

por Nath, Sangeeta, Dancourt, Julia, Shteyn, Vladimir, Puente, Gabriella, Fong, Wendy M., Nag, Shanta, Bewersdorf, Joerg, Yamamoto, Ai, Antonny, Bruno, Melia., Thomas J.
Publicado 2014

ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation

por Korfhage, Justin L., Wan, Neng, Elhan, Helin, Kauffman, Lisa, Pineda, Mia, Fuller, Devin M., Thiam, Abdou Rachid, Reinisch, Karin M., Melia, Thomas J.
Publicado 2023

ATG9 vesicles comprise the seed membrane of mammalian autophagosomes

por Olivas, Taryn J., Wu, Yumei, Yu, Shenliang, Luan, Lin, Choi, Peter, Guinn, Emily D., Nag, Shanta, De Camilli, Pietro V., Gupta, Kallol, Melia, Thomas J.
Publicado 2023

Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins

por Melia, Thomas J., Weber, Thomas, McNew, James A., Fisher, Lillian E., Johnston, Robert J., Parlati, Frank, Mahal, Lara K., Söllner, Thomas H., Rothman, James E.
Publicado 2002

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

por Holland, Petter, Knævelsrud, Helene, Søreng, Kristiane, Mathai, Benan J., Lystad, Alf Håkon, Pankiv, Serhiy, Bjørndal, Gunnveig T., Schultz, Sebastian W., Lobert, Viola H., Chan, Robin B., Zhou, Bowen, Liestøl, Knut, Carlsson, Sven R., Melia, Thomas J., Di Paolo, Gilbert, Simonsen, Anne
Publicado 2016