Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors

por Melick, Chase H., Jewell, Jenna L.
Publicado 2020

Regulation of mTORC1 by Upstream Stimuli

por Melick, Chase H., Jewell, Jenna L.
Publicado 2020

G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation

por Melick, Chase H., Lama-Sherpa, Tshering D., Curukovic, Adna, Jewell, Jenna L.
Publicado 2022

ArfGAP1 inhibits mTORC1 lysosomal localization and activation

por Meng, Delong, Yang, Qianmei, Melick, Chase H, Park, Brenden C, Hsieh, Ting‐Sung, Curukovic, Adna, Jeong, Mi‐Hyeon, Zhang, Junmei, James, Nicholas G, Jewell, Jenna L
Publicado 2021

AKAP13 couples GPCR signaling to mTORC1 inhibition

por Zhang, Shihai, Wang, Huanyu, Melick, Chase H., Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Lama-Sherpa, Tshering D., Meng, Delong, Servage, Kelly A., James, Nicholas G., Jewell, Jenna L.
Publicado 2021

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

por Jewell, Jenna L, Fu, Vivian, Hong, Audrey W, Yu, Fa-Xing, Meng, Delong, Melick, Chase H, Wang, Huanyu, Lam, Wai-Ling Macrina, Yuan, Hai-Xin, Taylor, Susan S, Guan, Kun-Liang
Publicado 2019

SNAT7 regulates mTORC1 via macropinocytosis

por Meng, Delong, Yang, Qianmei, Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Melick, Chase H., Lama-Sherpa, Tshering D., Wang, Huanyu, Huerta-Rosario, Mariela, Urquhart, Greg, Zacharias, Lauren G., Lewis, Cheryl, DeBerardinis, Ralph J., Jewell, Jenna L.
Publicado 2022