Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks

por Schwab, Karima, Melis, Valeria, Harrington, Charles R., Wischik, Claude M., Magbagbeolu, Mandy, Theuring, Franz, Riedel, Gernot
Publicado 2021

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the line 66 model of frontotemporal dementia

por Lemke, Nora, Melis, Valeria, Lauer, Dilyara, Magbagbeolu, Mandy, Neumann, Boris, Harrington, Charles R., Riedel, Gernot, Wischik, Claude M., Theuring, Franz, Schwab, Karima
Publicado 2021

HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

por Santos, Renato X., Melis, Valeria, Goatman, Elizabeth A., Leith, Michael, Baddeley, Thomas C., Storey, John M. D., Riedel, Gernot, Wischik, Claude M., Harrington, Charles R.
Publicado 2022

Abnormal Cognition, Sleep, EEG and Brain Metabolism in a Novel Knock-In Alzheimer Mouse, PLB1

por Platt, Bettina, Drever, Benjamin, Koss, David, Stoppelkamp, Sandra, Jyoti, Amar, Plano, Andrea, Utan, Aneli, Merrick, Georgina, Ryan, Duncan, Melis, Valeria, Wan, Hong, Mingarelli, Marco, Porcu, Emanuele, Scrocchi, Louise, Welch, Andy, Riedel, Gernot
Publicado 2011

Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

por Riedel, Gernot, Klein, Jochen, Niewiadomska, Grazyna, Kondak, Constantin, Schwab, Karima, Lauer, Dilyara, Magbagbeolu, Mandy, Steczkowska, Marta, Zadrozny, Maciej, Wydrych, Malgorzata, Cranston, Anna, Melis, Valeria, Santos, Renato X., Theuring, Franz, Harrington, Charles R., Wischik, Claude M.
Publicado 2020

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

por Schwab, Karima, Frahm, Silke, Horsley, David, Rickard, Janet E., Melis, Valeria, Goatman, Elizabeth A., Magbagbeolu, Mandy, Douglas, Morag, Leith, Michael G., Baddeley, Thomas C., Storey, John M. D., Riedel, Gernot, Wischik, Claude M., Harrington, Charles R., Theuring, Franz
Publicado 2018

Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models

por Melis, Valeria, Magbagbeolu, Mandy, Rickard, Janet E., Horsley, David, Davidson, Kathleen, Harrington, Kathleen A., Goatman, Keith, Goatman, Elizabeth A., Deiana, Serena, Close, Steve P., Zabke, Claudia, Stamer, Karsten, Dietze, Silke, Schwab, Karima, Storey, John M.D., Harrington, Charles R., Wischik, Claude M., Theuring, Franz, Riedel, Gernot
Publicado 2015