Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study

por Jiang, Chen, Melles, Ronald B., Sangani, Poorab, Hoffmann, Thomas J., Hysi, Pirro G., Glymour, M. Maria, Jorgenson, Eric, Lachke, Salil A., Choquet, Hélène
Publicado 2023

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

por Choquet, Hélène, Melles, Ronald B., Anand, Deepti, Yin, Jie, Cuellar-Partida, Gabriel, Wang, Wei, Hoffmann, Thomas J., Nair, K. Saidas, Hysi, Pirro G., Lachke, Salil A., Jorgenson, Eric
Publicado 2021

A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia

por Jiang, Chen, Melles, Ronald B., Yin, Jie, Fan, Qiao, Guo, Xiaobo, Cheng, Ching-Yu, He, Mingguang, Mackey, David A., Guggenheim, Jeremy A., Klaver, Caroline, Nair, K. Saidas, Jorgenson, Eric, Choquet, Hélène
Publicado 2023

A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness

por Choquet, Hélène, Melles, Ronald B., Yin, Jie, Hoffmann, Thomas J., Thai, Khanh K., Kvale, Mark N., Banda, Yambazi, Hardcastle, Alison J., Tuft, Stephen J., Glymour, M. Maria, Schaefer, Catherine, Risch, Neil, Nair, K. Saidas, Hysi, Pirro G., Jorgenson, Eric
Publicado 2020

Hydroxychloroquine prescription trends and predictors for excess dosing per recent ophthalmology guidelines

por Jorge, April M., Melles, Ronald B., Zhang, Yuqing, Lu, Na, Rai, Sharan K., Young, Lucy H., Costenbader, Karen H., Ramsey-Goldman, Rosalind, Lim, S. Sam, Esdaile, John M., Clarke, Ann E., Urowitz, M. B., Askanase, Anca, Aranow, Cynthia, Petri, Michelle, Choi, Hyon
Publicado 2018

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

por Choquet, Hélène, Paylakhi, Seyyedhassan, Kneeland, Stephen C., Thai, Khanh K., Hoffmann, Thomas J., Yin, Jie, Kvale, Mark N., Banda, Yambazi, Tolman, Nicholas G., Williams, Pete A., Schaefer, Catherine, Melles, Ronald B., Risch, Neil, John, Simon W. M., Nair, K. Saidas, Jorgenson, Eric
Publicado 2018

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration

por Clark, Rosie, Lee, Samantha Sze-Yee, Du, Ran, Wang, Yining, Kneepkens, Sander C.M., Charng, Jason, Huang, Yu, Hunter, Michael L., Jiang, Chen, Tideman, J.Willem L., Melles, Ronald B., Klaver, Caroline C.W., Mackey, David A., Williams, Cathy, Choquet, Hélène, Ohno-Matsui, Kyoko, Guggenheim, Jeremy A.
Publicado 2023

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

por Hysi, Pirro G., Choquet, Hélène, Khawaja, Anthony P., Wojciechowski, Robert, Tedja, Milly S, Yin, Jie, Simcoe, Mark J., Patasova, Karina, Mahroo, Omar A., Thai, Khanh K, Cumberland, Phillippa M, Melles, Ronald B., Verhoeven, Virginie J.M., Vitart, Veronique, Segre, Ayellet, Stone, Richard A., Wareham, Nick, Hewitt, Alex W, Mackey, David A, Klaver, Caroline CW, MacGregor, Stuart, Khaw, Peng T., Foster, Paul J., Guggenheim, Jeremy A., Rahi, Jugnoo S, Jorgenson, Eric, Hammond, Christopher J
Publicado 2020

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

por Ferreira, Manuel A, Vonk, Judith M, Baurecht, Hansjörg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D, Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, van Dongen, Jenny, Lu, Yi, Rüschendorf, Franz, Esparza-Gordillo, Jorge, Medway, Chris W, Mountjoy, Edward, Burrows, Kimberley, Hummel, Oliver, Grosche, Sarah, Brumpton, Ben M, Witte, John S, Hottenga, Jouke-Jan, Willemsen, Gonneke, Zheng, Jie, Rodríguez, Elke, Hotze, Melanie, Franke, Andre, Revez, Joana A, Beesley, Jonathan, Matheson, Melanie C, Dharmage, Shyamali C, Bain, Lisa M, Fritsche, Lars G, Gabrielsen, Maiken E, Balliu, Brunilda, Nielsen, Jonas B, Zhou, Wei, Hveem, Kristian, Langhammer, Arnulf, Holmen, Oddgeir L, Løset, Mari, Abecasis, Gonçalo R, Willer, Cristen J, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Thompson, Philip J, Martin, Nicholas G, Duffy, David L, Novak, Natalija, Schulz, Holger, Karrasch, Stefan, Gieger, Christian, Strauch, Konstantin, Melles, Ronald B, Hinds, David A, Hübner, Norbert, Weidinger, Stephan, Magnusson, Patrik KE, Jansen, Rick, Jorgenson, Eric, Lee, Young-Ae, Boomsma, Dorret I, Almqvist, Catarina, Karlsson, Robert, Koppelman, Gerard H, Paternoster, Lavinia
Publicado 2017

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

por Hardcastle, Alison J., Liskova, Petra, Bykhovskaya, Yelena, McComish, Bennet J., Davidson, Alice E., Inglehearn, Chris F., Li, Xiaohui, Choquet, Hélène, Habeeb, Mahmoud, Lucas, Sionne E. M., Sahebjada, Srujana, Pontikos, Nikolas, Lopez, Karla E. Rojas, Khawaja, Anthony P., Ali, Manir, Dudakova, Lubica, Skalicka, Pavlina, Van Dooren, Bart T. H., Geerards, Annette J. M., Haudum, Christoph W., Faro, Valeria Lo, Tenen, Abi, Simcoe, Mark J., Patasova, Karina, Yarrand, Darioush, Yin, Jie, Siddiqui, Salina, Rice, Aine, Farraj, Layal Abi, Chen, Yii-Der Ida, Rahi, Jugnoo S., Krauss, Ronald M., Theusch, Elisabeth, Charlesworth, Jac C., Szczotka-Flynn, Loretta, Toomes, Carmel, Meester-Smoor, Magda A., Richardson, Andrea J., Mitchell, Paul A., Taylor, Kent D., Melles, Ronald B., Aldave, Anthony J., Mills, Richard A., Cao, Ke, Chan, Elsie, Daniell, Mark D., Wang, Jie Jin, Rotter, Jerome I., Hewitt, Alex W., MacGregor, Stuart, Klaver, Caroline C. W., Ramdas, Wishal D., Craig, Jamie E., Iyengar, Sudha K., O’Brart, David, Jorgenson, Eric, Baird, Paul N., Rabinowitz, Yaron S., Burdon, Kathryn P., Hammond, Chris J., Tuft, Stephen J., Hysi, Pirro G.
Publicado 2021

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

por Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.
Publicado 2021