Structure and Function of Recombinant versus Plasma-Derived von Willebrand Factor and Impact on Multimer Pharmacokinetics in von Willebrand Disease

por Gritsch, Herbert, Schrenk, Gerald, Weinhappl, Nina, Mellgård, Björn, Ewenstein, Bruce, Turecek, Peter L
Publicado 2022

P1602: ACUTE EPISODES IN PATIENTS WITH CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA RECEIVING PROPHYLAXIS: POST HOC ANALYSIS OF A RETROSPECTIVE CHART REVIEW STUDY

por Coppo, Paul, Scully, Marie, Hovinga, Johanna Kremer, Tarasco, Erika, Willock, Rosa, Aragon, Maria Jose, Patwari, Parth, Wang, Linda T., Cronin, Michael, Mellgård, Björn, Ayodele, Olulade, Du, Ping
Publicado 2023

Recombinant von Willebrand factor prophylaxis in patients with severe von Willebrand disease: phase 3 study results

por Leebeek, Frank W. G., Peyvandi, Flora, Escobar, Miguel, Tiede, Andreas, Castaman, Giancarlo, Wang, Michael, Wynn, Tung, Baptista, Jovanna, Wang, Yi, Zhang, Jingmei, Mellgård, Björn, Özen, Gülden
Publicado 2022

Recombinant ADAMTS13 reduces abnormally up-regulated von Willebrand factor in plasma from patients with severe COVID-19

por Turecek, Peter L., Peck, Rachel C., Rangarajan, Savita, Reilly-Stitt, Christopher, Laffan, Michael A., Kazmi, Rashid, James, Izabela, Dushianthan, Ahilanandan, Schrenk, Gerald, Gritsch, Herbert, Ewenstein, Bruce M., Mellgard, Bjorn, Erdlenbruch, Wolfhard, Jain, Nisha, Binder, Nikolaus B., Mumford, Andrew D.
Publicado 2021

S305: PHASE 2 RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY OF RECOMBINANT ADAMTS13 IN PATIENTS WITH IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA

por Scully, Marie, Baptista, Jovanna, Bhattacharya, Indranil, Cataland, Spero, Coppo, Paul, Cuccia, Loredana, Dutt, Tina, Susan Huang, Shih-Han, Pascual Izquierdo, Cristina, Eva Mingot-Castellano, María, Parnes, Aric, Pavenski, Katerina, Rajavel, Kavitha, Jarque, Isidro, Wang, Linda T., Fernández Zarzoso, Miguel, Zhu, Andy, Mellgård, Björn
Publicado 2023