Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?

por Mellor, Andrew L., Lemos, Henrique, Huang, Lei
Publicado 2017

Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme

por Marshall, Brendan, Keskin, Derin Benerci, Mellor, Andrew L
Publicado 2001

Altered Tryptophan Metabolism as a Paradigm for Good and Bad Aspects of Immune Privilege in Chronic Inflammatory Diseases

por Li, Lingqian, Huang, Lei, Lemos, Henrique P., Mautino, Mario, Mellor, Andrew L.
Publicado 2012

Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase

por Keskin, Derin B., Marshall, Brendan, Munn, David, Mellor, Andrew L., Gearhart, Debra A.
Publicado 2006

Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

por Munn, David H., Shafizadeh, Ebrahim, Attwood, John T., Bondarev, Igor, Pashine, Achal, Mellor, Andrew L.
Publicado 1999

Induction and Role of Indoleamine 2,3 Dioxygenase in Mouse Models of Influenza A Virus Infection

por Huang, Lei, Li, Lingqian, Klonowski, Kim D., Tompkins, S. Mark, Tripp, Ralph A., Mellor, Andrew L.
Publicado 2013

Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice

por Davison, Laura M., Liu, Jessica C., Huang, Lei, Carroll, Thomas M., Mellor, Andrew L., Jørgensen, Trine N.
Publicado 2019

Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity

por Lemos, Henrique, Ou, Rong, McCardle, Caroline, Lin, Yijun, Calver, Jessica, Minett, Jack, Chadli, Ahmed, Huang, Lei, Mellor, Andrew L
Publicado 2020

The immunotherapeutic role of indoleamine 2,3‐dioxygenase in head and neck squamous cell carcinoma: A systematic review

por Lin, Daniel J., Ng, James C. K., Huang, Lei, Robinson, Max, O’Hara, James, Wilson, Janet A., Mellor, Andrew L.
Publicado 2021

Co-treatments to Boost IDO Activity and Inhibit Production of Downstream Catabolites Induce Durable Suppression of Experimental Autoimmune Encephalomyelitis

por Lemos, Henrique, Mohamed, Eslam, Ou, Rong, McCardle, Caroline, Zheng, Xiaozhong, McGuire, Kris, Homer, Natalie Z. M., Mole, Damian J., Huang, Lei, Mellor, Andrew L.
Publicado 2020

A critical role for the programmed death ligand 1 in fetomaternal tolerance

por Guleria, Indira, Khosroshahi, Arezou, Ansari, Mohammed Javeed, Habicht, Antje, Azuma, Miyuki, Yagita, Hideo, Noelle, Randolph J., Coyle, Anthony, Mellor, Andrew L., Khoury, Samia J., Sayegh, Mohamed H.
Publicado 2005

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

por Huang, Lei, Ou, Rong, Rabelo de Souza, Guilherme, Cunha, Thiago M., Lemos, Henrique, Mohamed, Eslam, Li, Lingqian, Pacholczyk, Gabriela, Randall, Janice, Munn, David H., Mellor, Andrew L.
Publicado 2016

CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8(+) T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication

por Zhang, Yanmei, Wang, Nisha, Ding, Meilin, Yang, Yang, Wang, Zhimin, Huang, Lei, Zhu, Wei, Mellor, Andrew L., Hou, Xiaorui, Zhou, Chenfei, Yan, Ruiming, Wang, Wei, Wu, Sha
Publicado 2020

Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

por Zhou, Chenfei, Zhang, Yanmei, Yan, Ruiming, Huang, Lei, Mellor, Andrew L., Yang, Yang, Chen, Xiaojing, Wei, Wenfei, Wu, Xiangguang, Yu, Lan, Liang, Luojiao, Zhang, Dan, Wu, Sha, Wang, Wei
Publicado 2020

Indoleamine 2,3-Dioxygenase 1 (Ido1) Is Involved in the Control of Mouse Caput Epididymis Immune Environment

por Jrad-Lamine, Aicha, Henry-Berger, Joelle, Damon-Soubeyrand, Christelle, Saez, Fabrice, Kocer, Ayhan, Janny, Laurent, Pons-Rejraji, Hanae, Munn, David H., Mellor, Andrew L., Gharbi, Najoua, Cadet, Rémi, Guiton, Rachel, Aitken, Robert J., Drevet, Joël R.
Publicado 2013

CD73 on cancer-associated fibroblasts enhanced by the A(2B)-mediated feedforward circuit enforces an immune checkpoint

por Yu, Miao, Guo, Gang, Huang, Lei, Deng, Libin, Chang, Chang-Sheng, Achyut, Bhagelu R., Canning, Madison, Xu, Ningchun, Arbab, Ali S., Bollag, Roni J., Rodriguez, Paulo C., Mellor, Andrew L., Shi, Huidong, Munn, David H., Cui, Yan
Publicado 2020

The PTEN pathway in T(regs) is a critical driver of the suppressive tumor microenvironment

por Sharma, Madhav D., Shinde, Rahul, McGaha, Tracy L., Huang, Lei, Holmgaard, Rikke B., Wolchok, Jedd D., Mautino, Mario R., Celis, Esteban, Sharpe, Arlene H., Francisco, Loise M., Powell, Jonathan D., Yagita, Hideo, Mellor, Andrew L., Blazar, Bruce R., Munn, David H.
Publicado 2015

Kynurenine is a novel endothelium-derived vascular relaxing factor produced during inflammation

por Wang, Yutang, Liu, Hanzhong, McKenzie, Gavin, Witting, Paul K, Stasch, Johannes-Peter, Hahn, Michael, Jackman, Katherine A, Changsirivathanathamrong, Dechaboon, Wu, Ben J, Ball, Helen J, Thomas, Shane R, Celermajer, David S, Mellor, Andrew L, Sobey, Chris G, Keaney, John F, Hunt, Nicholas H, Stocker, Roland
Publicado 2009

The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma

por Li, Minghui, Bolduc, Aaron R, Hoda, Md Nasrul, Gamble, Denise N, Dolisca, Sarah-Bianca, Bolduc, Anna K, Hoang, Kelly, Ashley, Claire, McCall, David, Rojiani, Amyn M, Maria, Bernard L, Rixe, Olivier, MacDonald, Tobey J, Heeger, Peter S, Mellor, Andrew L, Munn, David H, Johnson, Theodore S
Publicado 2014