Severe steroid-resistant anti-PD1 T-cell checkpoint inhibitor-induced hepatotoxicity driven by biliary injury

per Doherty, Gary Joseph, Duckworth, Adam M, Davies, Susan E, Mells, George F, Brais, Rebecca, Harden, Susan V, Parkinson, Christine A, Corrie, Pippa G
Publicat 2017

Clinical application of the GLOBE and United Kingdom‐primary biliary cholangitis risk scores in a trial cohort of patients with primary biliary cholangitis

per Carbone, Marco, Harms, Maren H., Lammers, Willem J., Marmon, Tonya, Pencek, Richard, MacConell, Leigh, Shapiro, David, Jones, David E., Mells, George F., Hansen, Bettina E.
Publicat 2018

Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

per Darlay, Rebecca, Ayers, Kristin L., Mells, George F., Hall, Lynsey S., Liu, Jimmy Z., Almarri, Mohamed A., Alexander, Graeme J., Jones, David E., Sandford, Richard N., Anderson, Carl A., Cordell, Heather J.
Publicat 2018

Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells

per Mulcahy, Victoria, Liaskou, Evaggelia, Martin, Jose-Ezequiel, Kotagiri, Prasanti, Badrock, Jonathan, Jones, Rebecca L., Rushbrook, Simon M, Ryder, Stephen D., Thorburn, Douglas, Taylor-Robinson, Simon D., Clark, Graeme, Cordell, Heather J., Sandford, Richard N., Jones, David E., Hirschfield, Gideon M., Mells, George F.
Publicat 2023

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

per Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M., Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A
Publicat 2012

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

per Mells, George F., Floyd, James A.B., Morley, Katherine I., Cordell, Heather J., Franklin, Christopher S., Shin, So-Youn, Heneghan, Michael A., Neuberger, James M., Donaldson, Peter T., Day, Darren B., Ducker, Samantha J., Muriithi, Agnes W., Wheater, Elizabeth F., Hammond, Christopher J., Dawwas, Muhammad F., Jones, David E., Peltonen, Leena, Alexander, Graeme J., Sandford, Richard N., Anderson, Carl A.
Publicat 2011

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

per Cordell, Heather J., Han, Younghun, Mells, George F., Li, Yafang, Hirschfield, Gideon M., Greene, Casey S., Xie, Gang, Juran, Brian D., Zhu, Dakai, Qian, David C., Floyd, James A. B., Morley, Katherine I., Prati, Daniele, Lleo, Ana, Cusi, Daniele, Gershwin, M. Eric, Anderson, Carl A., Lazaridis, Konstantinos N., Invernizzi, Pietro, Seldin, Michael F., Sandford, Richard N., Amos, Christopher I., Siminovitch, Katherine A.
Publicat 2015

Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System

per Goode, Elizabeth C., Clark, Allan B., Mells, George F., Srivastava, Brijesh, Spiess, Kelly, Gelson, William T.H., Trivedi, Palak J., Lynch, Kate D., Castren, Edit, Vesterhus, Mette N., Karlsen, Tom H., Ji, Sun‐Gou, Anderson, Carl A., Thorburn, Douglas, Hudson, Mark, Heneghan, Michael A., Aldersley, Mark A., Bathgate, Andrew, Sandford, Richard N., Alexander, Graeme J., Chapman, Roger W., Walmsley, Martine, Hirschfield, Gideon M., Rushbrook, Simon M.
Publicat 2019

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

per Cordell, Heather J., Fryett, James J., Ueno, Kazuko, Darlay, Rebecca, Aiba, Yoshihiro, Hitomi, Yuki, Kawashima, Minae, Nishida, Nao, Khor, Seik-Soon, Gervais, Olivier, Kawai, Yosuke, Nagasaki, Masao, Tokunaga, Katsushi, Tang, Ruqi, Shi, Yongyong, Li, Zhiqiang, Juran, Brian D., Atkinson, Elizabeth J., Gerussi, Alessio, Carbone, Marco, Asselta, Rosanna, Cheung, Angela, de Andrade, Mariza, Baras, Aris, Horowitz, Julie, Ferreira, Manuel A.R., Sun, Dylan, Jones, David E., Flack, Steven, Spicer, Ann, Mulcahy, Victoria L., Byan, Jinyoung, Han, Younghun, Sandford, Richard N., Lazaridis, Konstantinos N., Amos, Christopher I., Hirschfield, Gideon M., Seldin, Michael F., Invernizzi, Pietro, Siminovitch, Katherine A., Ma, Xiong, Nakamura, Minoru, Mells, George F.
Publicat 2021

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

per Cordell, Heather J., Fryett, James J., Ueno, Kazuko, Darlay, Rebecca, Aiba, Yoshihiro, Hitomi, Yuki, Kawashima, Minae, Nishida, Nao, Khor, Seik-Soon, Gervais, Olivier, Kawai, Yosuke, Nagasaki, Masao, Tokunaga, Katsushi, Tang, Ruqi, Shi, Yongyong, Li, Zhiqiang, Juran, Brian D., Atkinson, Elizabeth J., Gerussi, Alessio, Carbone, Marco, Asselta, Rosanna, Cheung, Angela, de Andrade, Mariza, Baras, Aris, Horowitz, Julie, Ferreira, Manuel A.R., Sun, Dylan, Jones, David E., Flack, Steven, Spicer, Ann, Mulcahy, Victoria L., Byun, Jinyoung, Han, Younghun, Sandford, Richard N., Lazaridis, Konstantinos N., Amos, Christopher I., Hirschfield, Gideon M., Seldin, Michael F., Invernizzi, Pietro, Siminovitch, Katherine A., Ma, Xiong, Nakamura, Minoru, Mells, George F.
Publicat 2022

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

per Brevini, Teresa, Maes, Mailis, Webb, Gwilym J., John, Binu V., Fuchs, Claudia D., Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L., Scott, William E., Pereyra-Gerber, Pehuén, Gelson, William T. H., Brown, Stephanie, Dillon, Scott, Muraro, Daniele, Sharp, Jo, Neary, Megan, Box, Helen, Tatham, Lee, Stewart, James, Curley, Paul, Pertinez, Henry, Forrest, Sally, Mlcochova, Petra, Varankar, Sagar S., Darvish-Damavandi, Mahnaz, Mulcahy, Victoria L., Kuc, Rhoda E., Williams, Thomas L., Heslop, James A., Rossetti, Davide, Tysoe, Olivia C., Galanakis, Vasileios, Vila-Gonzalez, Marta, Crozier, Thomas W. M., Bargehr, Johannes, Sinha, Sanjay, Upponi, Sara S., Fear, Corrina, Swift, Lisa, Saeb-Parsy, Kourosh, Davies, Susan E., Wester, Axel, Hagström, Hannes, Melum, Espen, Clements, Darran, Humphreys, Peter, Herriott, Jo, Kijak, Edyta, Cox, Helen, Bramwell, Chloe, Valentijn, Anthony, Illingworth, Christopher J. R., Dahman, Bassam, Bastaich, Dustin R., Ferreira, Raphaella D., Marjot, Thomas, Barnes, Eleanor, Moon, Andrew M., Barritt, Alfred S., Gupta, Ravindra K., Baker, Stephen, Davenport, Anthony P., Corbett, Gareth, Gorgoulis, Vassilis G., Buczacki, Simon J. A., Lee, Joo-Hyeon, Matheson, Nicholas J., Trauner, Michael, Fisher, Andrew J., Gibbs, Paul, Butler, Andrew J., Watson, Christopher J. E., Mells, George F., Dougan, Gordon, Owen, Andrew, Lohse, Ansgar W., Vallier, Ludovic, Sampaziotis, Fotios
Publicat 2022