Adaptation to Chronic-Cycling Hypoxia Renders Cancer Cells Resistant to MTH1-Inhibitor Treatment Which Can Be Counteracted by Glutathione Depletion

por Hansel, Christine, Hlouschek, Julian, Xiang, Kexu, Melnikova, Margarita, Thomale, Juergen, Helleday, Thomas, Jendrossek, Verena, Matschke, Johann
Publicado 2021

Multifaceted Mechanisms of Cisplatin Resistance in Long-Term Treated Urothelial Carcinoma Cell Lines

por Skowron, Margaretha A., Melnikova, Margarita, van Roermund, Joep G. H., Romano, Andrea, Albers, Peter, Thomale, Jürgen, Schulz, Wolfgang A., Niegisch, Günter, Hoffmann, Michèle J.
Publicado 2018

Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells

por Melnikova, Margarita, Wauer, Ulrike Sophie, Mendus, Diana, Hilger, Ralf Axel, Oliver, Trudy G., Mercer, Kim, Gohlke, Björn Oliver, Erdmann, Kati, Niederacher, Dieter, Neubauer, Hans, Buderath, Paul, Wimberger, Pauline, Kuhlmann, Jan Dominik, Thomale, Jürgen
Publicado 2020