Phenylthiocarbamate or N-Carbothiophenyl Group Chemistry in Peptide Synthesis and Bioconjugation

por Melnyk, Oleg, Ollivier, Nathalie, Besret, Soizic, Melnyk, Patricia
Publicado 2014

(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators

por Rami, Marouan, Winum, Jean-Yves, Supuran, Claudiu T., Melnyk, Patricia, Yous, Saïd
Publicado 2019

Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders

por Sileo, Pasquale, Simonin, Clémence, Melnyk, Patricia, Chartier-Harlin, Marie-Christine, Cotelle, Philippe
Publicado 2022

A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APP(Swe)/PSEN1(ΔE9) Mice Model of Amyloid Patho...

por Tautou, Marie, Descamps, Florian, Larchanché, Paul-Emmanuel, Buée, Luc, El Bakali, Jamal, Melnyk, Patricia, Sergeant, Nicolas
Publicado 2023

Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke

por Gelé, Patrick, Vingtdeux, Valérie, Potey, Camille, Drobecq, Hervé, Ghestem, Antoine, Melnyk, Patricia, Buée, Luc, Sergeant, Nicolas, Bordet, Régis
Publicado 2014

Thiocarbamate-Linked Polysulfonate–Peptide Conjugates As Selective Hepatocyte Growth Factor Receptor Binders

por Besret, Soizic, Vicogne, Jérôme, Dahmani, Fatima, Fafeur, Véronique, Desmet, Rémi, Drobecq, Hervé, Romieu, Anthony, Melnyk, Patricia, Melnyk, Oleg
Publicado 2014

Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A(2A) receptor

por Duroux, Romain, Renault, Nicolas, Cuelho, Joana Esteves, Agouridas, Laurence, Blum, David, Lopes, Luisa V., Melnyk, Patricia, Yous, Saïd
Publicado 2017

Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles

por Mesangeau, Christophe, Carato, Pascal, Renault, Nicolas, Coevoet, Mathilde, Larchanché, Paul-Emmanuel, Barczyk, Amélie, Buée, Luc, Sergeant, Nicolas, Melnyk, Patricia
Publicado 2022

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing

por Evrard, Caroline, Kienlen-Campard, Pascal, Coevoet, Mathilde, Opsomer, Rémi, Tasiaux, Bernadette, Melnyk, Patricia, Octave, Jean-Noël, Buée, Luc, Sergeant, Nicolas, Vingtdeux, Valérie
Publicado 2018

MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis

por Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Bencheikh, Yamina, Ravez, Severine, Quenon, Camille, Drucbert, Anne-Sophie, Foulon, Catherine, Melnyk, Patricia, Seuningen, Isabelle Van, Lebègue, Nicolas
Publicado 2019

Publisher Correction: MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis

por Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Bencheikh, Yamina, Ravez, Severine, Quenon, Camille, Drucbert, Anne-Sophie, Foulon, Catherine, Melnyk, Patricia, Van Seuningen, Isabelle, Lebègue, Nicolas
Publicado 2020

Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists

por Hurtevent, Aurélie, Le Naour, Morgan, Leclerc, Veronique, Carato, Pascal, Melnyk, Patricia, Hennuyer, Nathalie, Staels, Bart, Beucher-Gaudin, Monique, Caignard, Daniel-Henri, Dacquet, Catherine, Lebegue, Nicolas
Publicado 2020

Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis

por Oxombre, Bénédicte, Madouri, Fahima, Journé, Anne-Sophie, Ravez, Séverine, Woitrain, Eloise, Odou, Pascal, Duhal, Nathalie, Ninni, Sandro, Montaigne, David, Delhem, Nadira, Vermersch, Patrick, Melnyk, Patricia
Publicado 2022

A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration

por Tautou, Marie, Eddarkaoui, Sabiha, Descamps, Florian, Larchanché, Paul-Emmanuel, El Bakali, Jamal, Goveas, Liesel Mary, Dumoulin, Mélanie, Lamarre, Chloé, Blum, David, Buée, Luc, Melnyk, Patricia, Sergeant, Nicolas
Publicado 2021

The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis

por Stoup, Nicolas, Liberelle, Maxime, Schulz, Céline, Cavdarli, Sumeyye, Vasseur, Romain, Magnez, Romain, Lahdaoui, Fatima, Skrypek, Nicolas, Peretti, Fabien, Frénois, Frédéric, Thuru, Xavier, Melnyk, Patricia, Renault, Nicolas, Jonckheere, Nicolas, Lebègue, Nicolas, Van Seuningen, Isabelle
Publicado 2021

Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface

por Gibault, Floriane, Coevoet, Mathilde, Sturbaut, Manon, Farce, Amaury, Renault, Nicolas, Allemand, Frédéric, Guichou, Jean-François, Drucbert, Anne-Sophie, Foulon, Catherine, Magnez, Romain, Thuru, Xavier, Corvaisier, Matthieu, Huet, Guillemette, Chavatte, Philippe, Melnyk, Patricia, Bailly, Fabrice, Cotelle, Philippe
Publicado 2018

A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively

por Marchand, Antoine, Sarchione, Alessia, Athanasopoulos, Panagiotis S., Roy, Hélène Bauderlique-Le, Goveas, Liesel, Magnez, Romain, Drouyer, Matthieu, Emanuele, Marco, Ho, Franz Y., Liberelle, Maxime, Melnyk, Patricia, Lebègue, Nicolas, Thuru, Xavier, Nichols, R. Jeremy, Greggio, Elisa, Kortholt, Arjan, Galli, Thierry, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc
Publicado 2022