De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding R...

por Hassan, Musa A, Melo, Mariane B, Haas, Brian, Jensen, Kirk D C, Saeij, Jeroen P J
Publicado 2012

IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells

por Lu, Zeyu, Truex, Nicholas L., Melo, Mariane B., Cheng, Yiran, Li, Na, Irvine, Darrell J., Pentelute, Bradley L.
Publicado 2021

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

por Barberio, Antonio E., Smith, Sean G., Pires, Ivan S., Iyer, Sonia, Reinhardt, Ferenc, Melo, Mariane B., Suh, Heikyung, Weinberg, Robert A., Irvine, Darrell J., Hammond, Paula T.
Publicado 2022

UNC93B1 Mediates Host Resistance to Infection with Toxoplasma gondii

por Melo, Mariane B., Kasperkovitz, Pia, Cerny, Anna, Könen-Waisman, Stephanie, Kurt-Jones, Evelyn A., Lien, Egil, Beutler, Bruce, Howard, Jonathan C., Golenbock, Douglas T., Gazzinelli, Ricardo T.
Publicado 2010

Temporal dynamics of intradermal cytokine response to tuberculin in Mycobacterium bovis BCG-vaccinated cattle using sampling microneedles

por Steinbach, Sabine, Jalili-Firoozinezhad, Sasan, Srinivasan, Sreenidhi, Melo, Mariane B., Middleton, Sonya, Konold, Timm, Coad, Michael, Hammond, Paula T., Irvine, Darrell J., Vordermeier, Martin, Kapur, Vivek
Publicado 2021

Optimization of storage conditions for lipid nanoparticle-formulated self-replicating RNA vaccines

por Kim, Byungji, Hosn, Ryan R., Remba, Tanaka, Yun, Dongsoo, Li, Na, Abraham, Wuhbet, Melo, Mariane B., Cortes, Manuel, Li, Bridget, Zhang, Yuebao, Dong, Yizhou, Irvine, Darrell J.
Publicado 2023

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

por Niedelman, Wendy, Gold, Daniel A., Rosowski, Emily E., Sprokholt, Joris K., Lim, Daniel, Farid Arenas, Ailan, Melo, Mariane B., Spooner, Eric, Yaffe, Michael B., Saeij, Jeroen P. J.
Publicado 2012

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination

por Jensen, Kirk D. C., Camejo, Ana, Melo, Mariane B., Cordeiro, Cynthia, Julien, Lindsay, Grotenbreg, Gijsbert M., Frickel, Eva-Maria, Ploegh, Hidde L., Young, Lucy, Saeij, Jeroen P. J.
Publicado 2015

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

por Gorfu, Gezahegn, Cirelli, Kimberly M., Melo, Mariane B., Mayer-Barber, Katrin, Crown, Devorah, Koller, Beverly H., Masters, Seth, Sher, Alan, Leppla, Stephen H., Moayeri, Mahtab, Saeij, Jeroen P. J., Grigg, Michael E.
Publicado 2014

Optimization of an alum-anchored clinical HIV vaccine candidate

por Rodrigues, Kristen A., Cottrell, Christopher A., Steichen, Jon M., Groschel, Bettina, Abraham, Wuhbet, Suh, Heikyung, Agarwal, Yash, Ni, Kaiyuan, Chang, Jason Y. H., Yousefpour, Parisa, Melo, Mariane B., Schief, William R., Irvine, Darrell J.
Publicado 2023

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

por Tokatlian, Talar, Kulp, Daniel W., Mutafyan, Andrew A., Jones, Christopher A., Menis, Sergey, Georgeson, Erik, Kubitz, Mike, Zhang, Michael H., Melo, Mariane B., Silva, Murillo, Yun, Dong Soo, Schief, William R., Irvine, Darrell J.
Publicado 2018

Co‐Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced‐Humoral Immunity

por Chang, Jason Y. H., Agarwal, Yash, Rodrigues, Kristen A., Momin, Noor, Ni, Kaiyuan, Read, Benjamin J., Moyer, Tyson J., Mehta, Naveen K., Silva, Murillo, Suh, Heikyung, Melo, Mariane B., Wittrup, K. Dane, Irvine, Darrell J.
Publicado 2022

Transcriptional Analysis of Murine Macrophages Infected with Different Toxoplasma Strains Identifies Novel Regulation of Host Signaling Pathways

por Melo, Mariane B., Nguyen, Quynh P., Cordeiro, Cynthia, Hassan, Musa A., Yang, Ninghan, McKell, Renée, Rosowski, Emily E., Julien, Lindsay, Butty, Vincent, Dardé, Marie-Laure, Ajzenberg, Daniel, Fitzgerald, Katherine, Young, Lucy H., Saeij, Jeroen P. J.
Publicado 2013

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

por Agarwal, Yash, Milling, Lauren E., Chang, Jason Y.H., Santollani, Luciano, Sheen, Allison, Lutz, Emi A., Tabet, Anthony, Stinson, Jordan, Ni, Kaiyuan, Rodrigues, Kristen A., Moyer, Tyson J., Melo, Mariane B., Irvine, Darrell J., Wittrup, K. Dane
Publicado 2022

STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity

por Dane, Eric L., Belessiotis-Richards, Alexis, Backlund, Coralie, Wang, Jianing, Hidaka, Kousuke, Milling, Lauren E., Bhagchandani, Sachin, Melo, Mariane B., Wu, Shengwei, Li, Na, Donahue, Nathan, Ni, Kaiyuan, Ma, Leyuan, Okaniwa, Masanori, Stevens, Molly M., Alexander-Katz, Alfredo, Irvine, Darrell J.
Publicado 2022

Safety, immunogenicity and efficacy of an mRNA-based COVID-19 vaccine, GLB-COV2-043, in preclinical animal models

por Lelis, Felipe, Byk, Laura A., Pustylnikov, Sergei, Nguyen, Vivian, Nguyen, Brandon, Nitz, Malorie, Tarte, Prutha, Tungare, Kunal, Li, Jilong, Manna, Saikat, Maiti, Sampa, Mehta, Dhwani H., Sekar, Narendran, Posadas, Diana M., Dhamankar, Himanshu, Hughes, Jeffrey A., Aulisa, Lorenzo, Khan, Amin, Melo, Mariane B., Dey, Antu K.
Publicado 2023

Engineered immunogen binding to alum adjuvant enhances humoral immunity

por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado 2020

Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado 2020

Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity

por Hartwell, Brittany L., Melo, Mariane B., Xiao, Peng, Lemnios, Ashley A., Li, Na, Chang, Jason Y.H., Yu, Jingyou, Gebre, Makda S., Chang, Aiquan, Maiorino, Laura, Carter, Crystal, Moyer, Tyson J., Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Rodrigues, Kristen A., Silva, Murillo, Suh, Heikyung, Adams, Josetta, Fontenot, Jane, Love, J. Christopher, Barouch, Dan H., Villinger, Francois, Ruprecht, Ruth M., Irvine, Darrell J.
Publicado 2022