DNA repair endonuclease ERCC1–XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy

por McNeil, Ewan M., Melton, David W.
Publicado 2012

Disruption of DNA repair in cancer cells by ubiquitination of a destabilising dimerization domain of nucleotide excision repair protein ERCC1

por Yang, Lanlan, Ritchie, Ann-Marie, Melton, David W.
Publicado 2017

Improved Coinfection with Amphotropic Pseudotyped Retroviral Vectors

por Wu, Yuehong, Melton, David W., Zhang, Yong, Hornsby, Peter J.
Publicado 2009

Deletion of Genes Implicated in Protecting the Integrity of Male Germ Cells Has Differential Effects on the Incidence of DNA Breaks and Germ Cell Loss

por Paul, Catriona, Povey, Joanne E., Lawrence, Nicola J., Selfridge, Jim, Melton, David W., Saunders, Philippa T. K.
Publicado 2007

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates

por Magin, Thomas M., Schröder, Rolf, Leitgeb, Sabine, Wanninger, Frederique, Zatloukal, Kurt, Grund, Christine, Melton, David W.
Publicado 1998

Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ζ

por Song, Liang, McNeil, Ewan M., Ritchie, Ann-Marie, Astell, Katy R., Gourley, Charlie, Melton, David W.
Publicado 2017

Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles

por Ramirez, Ricardo, Herrera, Allen Michael, Ramirez, Joshua, Qian, Chunjiang, Melton, David W., Shireman, Paula K., Jin, Yu-Fang
Publicado 2019

Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells

por Gomez, Miriam K., Illuzzi, Giuditta, Colomer, Carlota, Churchman, Michael, Hollis, Robert L., O’Connor, Mark J., Gourley, Charlie, Leo, Elisabetta, Melton, David W.
Publicado 2020

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

por Zhou, Linna, Ishizaki, Hironori, Spitzer, Michaela, Taylor, Kerrie L., Temperley, Nicholas D., Johnson, Stephen L., Brear, Paul, Gautier, Philippe, Zeng, Zhiqiang, Mitchell, Amy, Narayan, Vikram, McNeil, Ewan M., Melton, David W., Smith, Terry K., Tyers, Mike, Westwood, Nicholas J., Patton, E. Elizabeth
Publicado 2012

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

por Zhou, Linna, Ishizaki, Hironori, Spitzer, Michaela, Taylor, Kerrie L., Temperley, Nicholas D., Johnson, Stephen L., Brear, Paul, Gautier, Philippe, Zeng, Zhiqiang, Mitchell, Amy, Narayan, Vikram, McNeil, Ewan M., Melton, David W., Smith, Terry K., Tyers, Mike, Westwood, Nicholas J., Patton, E. Elizabeth
Publicado 2020