Shiga toxin (Stx) type 2‐induced increase in O‐linked N‐acetyl glucosamine protein modification: a new therapeutic target?

por Bova, Rebecca A, Melton‐Celsa, Angela
Publicado 2021

Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing Escherichia coli in Mice

por Atitkar, Rama R., Melton-Celsa, Angela R.
Publicado 2023

Shiga Toxin Type 2dact Displays Increased Binding to Globotriaosylceramide in vitro and Increased Lethality in Mice after Activation by Elastase

por Bunger, Joshua C., Melton-Celsa, Angela R., O’Brien, Alison D.
Publicado 2013

When a healthy diet turns deadly

por Zumbrun, Steven D, Melton-Celsa, Angela R, O’Brien, Alison D
Publicado 2014

Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a

por Russo, Lisa M., Melton-Celsa, Angela R., O'Brien, Alison D.
Publicado 2016

Comparisons of Native Shiga Toxins (Stxs) Type 1 and 2 with Chimeric Toxins Indicate that the Source of the Binding Subunit Dictates Degree of Toxicity

por Russo, Lisa M., Melton-Celsa, Angela R., Smith, Michael J., O'Brien, Alison D.
Publicado 2014

Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

por Bunger, Joshua C., Melton-Celsa, Angela R., Maynard, Ernest L., O’Brien, Alison D.
Publicado 2015

Shiga toxin 2a and Enteroaggregative Escherichia coli – a deadly combination

por Boisen, Nadia, Melton-Celsa, Angela R, Scheutz, Flemming, O'Brien, Alison D, Nataro, James P
Publicado 2015

Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice

por Russo, Lisa M., Abdeltawab, Nourtan F., O’Brien, Alison D., Kotb, Malak, Melton-Celsa, Angela R.
Publicado 2015

Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice

por McNichol, Beth A., Bova, Rebecca A., Torres, Kieron, Preston, Lan N., Melton-Celsa, Angela R.
Publicado 2021

Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

por Gray, Miranda D., Lampel, Keith A., Strockbine, Nancy A., Fernandez, Reinaldo E., Melton-Celsa, Angela R., Maurelli, Anthony T.
Publicado 2014

Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

por Bova, Rebecca A., Lamont, Andrew C., Picou, Theodore J., Ho, Vincent B., Gilchrist, Kristin H., Melton-Celsa, Angela R.
Publicado 2023

Ricin Crosses Polarized Human Intestinal Cells and Intestines of Ricin-Gavaged Mice without Evident Damage and Then Disseminates to Mouse Kidneys

por Flora, Alyssa D., Teel, Louise D., Smith, Mark A., Sinclair, James F., Melton-Celsa, Angela R., O’Brien, Alison D.
Publicado 2013

The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

por Hauser, Jocelyn R., Atitkar, Rama R., Petro, Courtney D., Lindsey, Rebecca L., Strockbine, Nancy, O'Brien, Alison D., Melton-Celsa, Angela R.
Publicado 2020

Identification and Characterization of ten Escherichia coli Strains Encoding Novel Shiga Toxin 2 Subtypes, Stx2n as Well as Stx2j, Stx2m, and Stx2o, in the United States

por Lindsey, Rebecca L., Prasad, Arjun, Feldgarden, Michael, Gonzalez-Escalona, Narjol, Kapsak, Curtis, Klimke, William, Melton-Celsa, Angela, Smith, Peyton, Souvorov, Alexandre, Truong, Jenny, Scheutz, Flemming
Publicado 2023

The Role of the AggR Regulon in the Virulence of the Shiga Toxin-Producing Enteroaggregative Escherichia coli Epidemic O104:H4 Strain in Mice

por Boisen, Nadia, Melton-Celsa, Angela R., Hansen, Anne-Marie, Zangari, Tonia, Smith, Mark A., Russo, Lisa M., Scheutz, Flemming, O’Brien, Alison D., Nataro, James P.
Publicado 2019

Genetic and Virulence Profiles of Enteroaggregative Escherichia coli (EAEC) Isolated From Deployed Military Personnel (DMP) With Travelers' Diarrhea

por Petro, Courtney D., Duncan, Jeffrey K., Seldina, Yuliya I., Allué-Guardia, Anna, Eppinger, Mark, Riddle, Mark S., Tribble, David R., Johnson, Ryan C., Dalgard, Clifton L., Sukumar, Gauthaman, Connor, Patrick, Boisen, Nadia, Melton-Celsa, Angela R.
Publicado 2020