Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocryst...

por Dohle, Wolfgang, Prota, Andrea E., Menchon, Grégory, Hamel, Ernest, Steinmetz, Michel O., Potter, Barry V. L.
Publicado 2019

Anisomycin injection in area CA3 of the hippocampus impairs both short-term and long-term memories of contextual fear

por Remaud, Jessica, Ceccom, Johnatan, Carponcy, Julien, Dugué, Laura, Menchon, Gregory, Pech, Stéphane, Halley, Helene, Francés, Bernard, Dahan, Lionel
Publicado 2014

Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface

por Menchon, Grégory, Bombarde, Oriane, Trivedi, Mansi, Négrel, Aurélie, Inard, Cyril, Giudetti, Brigitte, Baltas, Michel, Milon, Alain, Modesti, Mauro, Czaplicki, Georges, Calsou, Patrick
Publicado 2016

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

por Menchon, Grégory, Prota, Andrea E., Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J. Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O.
Publicado 2018

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

por Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.
Publicado 2017

Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent

por Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.
Publicado 2020