Headway made towards biosignatures for incipient tuberculosis

por Scriba, Thomas J, Mendelsohn, Simon C
Publicado 2020

Meeting report: Virtual Global Forum on Tuberculosis Vaccines, 20–22 April 2021

por Suliman, Sara, Pelzer, Puck T., Shaku, Moagi, Rozot, Virginie, Mendelsohn, Simon C.
Publicado 2021

Blood transcriptional signatures for tuberculosis testing

por Mendelsohn, Simon C, Mbandi, Stanley Kimbung, Hatherill, Mark, Scriba, Thomas J
Publicado 2020

Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV

por Mendelsohn, Simon C, Verhage, Savannah, Mulenga, Humphrey, Scriba, Thomas J, Hatherill, Mark
Publicado 2023

sfkit: a web-based toolkit for secure and federated genomic analysis

por Mendelsohn, Simon, Froelicher, David, Loginov, Denis, Bernick, David, Berger, Bonnie, Cho, Hyunghoon
Publicado 2023

The impact of blood transcriptomic biomarker targeted tuberculosis preventive therapy in people living with HIV: a mathematical modelling study

por Sumner, Tom, Mendelsohn, Simon C., Scriba, Thomas J., Hatherill, Mark, White, Richard G.
Publicado 2021

Host blood transcriptomic biomarkers of tuberculosis disease in people living with HIV: a systematic review protocol

por Mendelsohn, Simon C, Mulenga, Humphrey, Mbandi, Stanley Kimbung, Darboe, Fatoumatta, Shelton, Mary, Scriba, Thomas J, Hatherill, Mark
Publicado 2021

Performance of host blood transcriptomic signatures for diagnosing and predicting progression to tuberculosis disease in HIV-negative adults and adolescents: a systematic review pr...

por Mulenga, Humphrey, Bunyasi, Erick Wekesa, Mbandi, Stanley Kimbung, Mendelsohn, Simon C, Kagina, Benjamin, Penn-Nicholson, Adam, Scriba, Thomas, Hatherill, Mark
Publicado 2019

Performance of diagnostic and predictive host blood transcriptomic signatures for Tuberculosis disease: A systematic review and meta-analysis

por Mulenga, Humphrey, Zauchenberger, Chambrez-Zita, Bunyasi, Erick W., Mbandi, Stanley Kimbung, Mendelsohn, Simon C., Kagina, Benjamin, Penn-Nicholson, Adam, Scriba, Thomas J., Hatherill, Mark
Publicado 2020

Regional changes in tuberculosis disease burden among adolescents in South Africa (2005–2015)

por Bunyasi, Erick Wekesa, Mulenga, Humphrey, Luabeya, Angelique K. K., Shenje, Justin, Mendelsohn, Simon C., Nemes, Elisa, Tameris, Michele, Wood, Robin, Scriba, Thomas J., Hatherill, Mark
Publicado 2020

Clinical predictors of pulmonary tuberculosis among South African adults with HIV

por Mendelsohn, Simon C., Fiore-Gartland, Andrew, Awany, Denis, Mulenga, Humphrey, Mbandi, Stanley Kimbung, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Scriba, Thomas J., Hatherill, Mark
Publicado 2022

The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk

por Mulenga, Humphrey, Fiore-Gartland, Andrew, Mendelsohn, Simon C., Penn-Nicholson, Adam, Mbandi, Stanley Kimbung, Borate, Bhavesh, Musvosvi, Munyaradzi, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Scriba, Thomas J., Hatherill, Mark
Publicado 2022

Evaluation of a transcriptomic signature of tuberculosis risk in combination with an interferon gamma release assay: A diagnostic test accuracy study

por Mulenga, Humphrey, Fiore-Gartland, Andrew, Mendelsohn, Simon C., Penn-Nicholson, Adam, Mbandi, Stanley Kimbung, Nemes, Elisa, Borate, Bhavesh, Musvosvi, Munyaradzi, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Scriba, Thomas J., Hatherill, Mark
Publicado 2022

IL27 gene expression distinguishes multisystem inflammatory syndrome in children from febrile illness in a South African cohort

por Spracklen, Timothy F., Mendelsohn, Simon C., Butters, Claire, Facey-Thomas, Heidi, Stander, Raphaella, Abrahams, Debbie, Erasmus, Mzwandile, Baguma, Richard, Day, Jonathan, Scott, Christiaan, Zühlke, Liesl J., Kassiotis, George, Scriba, Thomas J., Webb, Kate
Publicado 2022

Prospective multicentre head-to-head validation of host blood transcriptomic biomarkers for pulmonary tuberculosis by real-time PCR

por Mendelsohn, Simon C., Mbandi, Stanley Kimbung, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Musvosvi, Munyaradzi, Mulenga, Humphrey, Fisher, Michelle, Hadley, Katie, Erasmus, Mzwandile, Nombida, Onke, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark, Scriba, Thomas J.
Publicado 2022

Mycobacterium tuberculosis infection, immune activation, and risk of HIV acquisition

por Bender Ignacio, Rachel A., Long, Jessica, Saha, Aparajita, Nguyen, Felicia K., Joudeh, Lara, Valinetz, Ethan, Mendelsohn, Simon C., Scriba, Thomas J., Hatherill, Mark, Janes, Holly, Churchyard, Gavin, Buchbinder, Susan, Duerr, Ann, Shah, Javeed A., Hawn, Thomas R.
Publicado 2022

Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial

por Scriba, Thomas J, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Mulenga, Humphrey, Kimbung Mbandi, Stanley, Borate, Bhavesh, Mendelsohn, Simon C, Hadley, Katie, Hikuam, Chris, Kaskar, Masooda, Musvosvi, Munyaradzi, Bilek, Nicole, Self, Steven, Sumner, Tom, White, Richard G, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T, Hassan-Moosa, Razia, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark
Publicado 2021

Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study

por Mendelsohn, Simon C, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Mulenga, Humphrey, Mbandi, Stanley Kimbung, Borate, Bhavesh, Hadley, Katie, Hikuam, Chris, Musvosvi, Munyaradzi, Bilek, Nicole, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Nombida, Onke, Kaskar, Masooda, Sumner, Tom, White, Richard G, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T, Hassan-Moosa, Razia, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Scriba, Thomas J, Hatherill, Mark
Publicado 2021

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

por Penn-Nicholson, Adam, Mbandi, Stanley Kimbung, Thompson, Ethan, Mendelsohn, Simon C., Suliman, Sara, Chegou, Novel N., Malherbe, Stephanus T., Darboe, Fatoumatta, Erasmus, Mzwandile, Hanekom, Willem A., Bilek, Nicole, Fisher, Michelle, Kaufmann, Stefan H. E., Winter, Jill, Murphy, Melissa, Wood, Robin, Morrow, Carl, Van Rhijn, Ildiko, Moody, Branch, Murray, Megan, Andrade, Bruno B., Sterling, Timothy R., Sutherland, Jayne, Naidoo, Kogieleum, Padayatchi, Nesri, Walzl, Gerhard, Hatherill, Mark, Zak, Daniel, Scriba, Thomas J.
Publicado 2020

Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis

por Mulenga, Humphrey, Musvosvi, Munyaradzi, Mendelsohn, Simon C., Penn-Nicholson, Adam, Kimbung Mbandi, Stanley, Fiore-Gartland, Andrew, Tameris, Michèle, Mabwe, Simbarashe, Africa, Hadn, Bilek, Nicole, Kafaar, Fazlin, Khader, Shabaana A., Carstens, Balie, Hadley, Katie, Hikuam, Chris, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Nombida, Onke, Kaskar, Masooda, Nicol, Mark P., Mbhele, Slindile, Van Heerden, Judi, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T., Hassan-Moosa, Razia, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark, Scriba, Thomas J.
Publicado 2021