Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells

por Mendum, Tom A, Wu, Huihai, Kierzek, Andrzej M, Stewart, Graham R
Publicado 2015

Towards the Immunoproteome of Neisseria meningitidis

por Mendum, Tom A., Newcombe, Jane, McNeilly, Celia L., McFadden, Johnjoe
Publicado 2009

Interrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera

por Mendum, Tom A, Newcombe, Jane, Mannan, Ahmad A, Kierzek, Andrzej M, McFadden, Johnjoe
Publicado 2011

Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum

por Butler, Rachel E, Smith, Alex A., Mendum, Tom A., Chandran, Aneesh, Wu, Huihai, Lefrançois, Louise, Chambers, Mark, Soldati, Thierry, Stewart, Graham R
Publicado 2020

Systems-Based Approaches to Probing Metabolic Variation within the Mycobacterium tuberculosis Complex

por Lofthouse, Emma K., Wheeler, Paul R., Beste, Dany J. V., Khatri, Bhagwati L., Wu, Huihai, Mendum, Tom A., Kierzek, Andrzej M., McFadden, Johnjoe
Publicado 2013

Intracellular Mycobacterium tuberculosis Exploits Multiple Host Nitrogen Sources during Growth in Human Macrophages

por Borah, Khushboo, Beyß, Martin, Theorell, Axel, Wu, Huihai, Basu, Piyali, Mendum, Tom A., Nӧh, Katharina, Beste, Dany J.V., McFadden, Johnjoe
Publicado 2019

A systematic evaluation of Mycobacterium tuberculosis Genome-Scale Metabolic Networks

por López-Agudelo, Víctor A., Mendum, Tom A., Laing, Emma, Wu, HuiHai, Baena, Andres, Barrera, Luis F., Beste, Dany J. V., Rios-Estepa, Rigoberto
Publicado 2020

(13)C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

por Beste, Dany J.V., Nöh, Katharina, Niedenführ, Sebastian, Mendum, Tom A., Hawkins, Nathaniel D., Ward, Jane L., Beale, Michael H., Wiechert, Wolfgang, McFadden, Johnjoe
Publicado 2013

Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans...

por Hsieh, Louise Tzung-Harn, Hall, Belinda S., Newcombe, Jane, Mendum, Tom A., Umrania, Yagnesh, Deery, Michael J., Shi, Wei Q., Salguero, Francisco J., Simmonds, Rachel E
Publicado 2023

Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

por Borah, Khushboo, Girardi, Karina do Carmo de Vasconcelos, Mendum, Tom A., Lery, Leticia Miranda Santos, Beste, Dany J. V., Lara, Flavio Alves, Pessolani, Maria Cristina Vidal, McFadden, Johnjoe
Publicado 2019

Leprosy at the edge of Europe—Biomolecular, isotopic and osteoarchaeological findings from medieval Ireland

por Taylor, G. Michael, Murphy, Eileen M., Mendum, Tom A., Pike, Alistair W. G., Linscott, Bethan, Wu, Huihai, O’Grady, Justin, Richardson, Hollian, O’Donovan, Edmond, Troy, Carmelita, Stewart, Graham R.
Publicado 2018

Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic

por Mendum, Tom A, Schuenemann, Verena J, Roffey, Simon, Taylor, G Michael, Wu, Huihai, Singh, Pushpendra, Tucker, Katie, Hinds, Jason, Cole, Stewart T, Kierzek, Andrzej M, Nieselt, Kay, Krause, Johannes, Stewart, Graham R
Publicado 2014

The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

por Basu, Piyali, Sandhu, Noor, Bhatt, Apoorva, Singh, Albel, Balhana, Ricardo, Gobe, Irene, Crowhurst, Nicola A., Mendum, Tom A., Gao, Liang, Ward, Jane L., Beale, Michael H., McFadden, Johnjoe, Beste, Dany J. V.
Publicado 2018

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

por Mendum, Tom A., Chandran, Aneesh, Williams, Kerstin, Vordermeier, H. Martin, Villarreal-Ramos, Bernardo, Wu, H., Singh, Albel, Smith, Alex A., Butler, Rachel E., Prasad, Aravind, Bharti, Neeraj, Banerjee, Ruma, Kasibhatla, Sunitha M., Bhatt, Apoorva, Stewart, Graham R., McFadden, Johnjoe
Publicado 2019

Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis

por Borah, Khushboo, Mendum, Tom A, Hawkins, Nathaniel D, Ward, Jane L, Beale, Michael H, Larrouy‐Maumus, Gerald, Bhatt, Apoorva, Moulin, Martine, Haertlein, Michael, Strohmeier, Gernot, Pichler, Harald, Forsyth, V Trevor, Noack, Stephan, Goulding, Celia W, McFadden, Johnjoe, Beste, Dany J V
Publicado 2021