Mitochondrial apoptosis and BH3 mimetics

por Dai, Haiming, Meng, X. Wei, Kaufmann, Scott H.
Publicado 2016

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

por Dai, Haiming, Smith, Alyson, Meng, X. Wei, Schneider, Paula A., Pang, Yuan-Ping, Kaufmann, Scott H.
Publicado 2011

Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization

por Pang, Yuan-Ping, Dai, Haiming, Smith, Alyson, Meng, X. Wei, Schneider, Paula A., Kaufmann, Scott H.
Publicado 2012

Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells

por Dai, Haiming, Ding, Husheng, Meng, X. Wei, Peterson, Kevin L., Schneider, Paula A., Karp, Judith E., Kaufmann, Scott H.
Publicado 2015

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

por Sainski, Amy M., Dai, Haiming, Natesampillai, Sekar, Pang, Yuan-Ping, Bren, Gary D., Cummins, Nathan W., Correia, Cristina, Meng, X. Wei, Tarara, James E., Ramirez-Alvarado, Marina, Katzmann, David J., Ochsenbauer, Christina, Kappes, John C., Kaufmann, Scott H., Badley, Andrew D.
Publicado 2014

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

por Sainski, Amy M., Dai, Haiming, Natesampillai, Sekar, Pang, Yuan-Ping, Bren, Gary D., Cummins, Nathan W., Correia, Cristina, Meng, X. Wei, Tarara, James E., Ramirez-Alvarado, Marina, Katzmann, David J., Ochsenbauer, Christina, Kappes, John C., Kaufmann, Scott H., Badley, Andrew D.
Publicado 2014

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance

por O’Sullivan, Julia, Kothari, Charu, Caron, Marie-Christine, Gagné, Jean-Philippe, Jin, Zhigang, Nonfoux, Louis, Beneyton, Adèle, Coulombe, Yan, Thomas, Mélissa, Atalay, Nurgul, Meng, X Wei, Milano, Larissa, Jean, Dominique, Boisvert, François-Michel, Kaufmann, Scott H, Hendzel, Michael J, Masson, Jean-Yves, Poirier, Guy G
Publicado 2023

Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells

por Schroeder, Barbara, Vander Steen, Travis, Espinoza, Ingrid, Venkatapoorna, Chandra M. Kurapaty, Hu, Zeng, Silva, Fernando Martín, Regan, Kevin, Cuyàs, Elisabet, Meng, X. Wei, Verdura, Sara, Arbusà, Aina, Schneider, Paula A., Flatten, Karen S., Kemble, George, Montero, Joan, Kaufmann, Scott H., Menendez, Javier A., Lupu, Ruth
Publicado 2021

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance

por Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H
Publicado 2021