ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

por Towler, Paul, Staker, Bart, Prasad, Sridhar G., Menon, Saurabh, Tang, Jin, Parsons, Thomas, Ryan, Dominic, Fisher, Martin, Williams, David, Dales, Natalie A., Patane, Michael A., Pantoliano, Michael W.
Publicado 2004

TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies

por Carideo Cunniff, Elizabeth, Sato, Yosuke, Mai, Doanh, Appleman, Vicky A., Iwasaki, Shinji, Kolev, Vihren, Matsuda, Atsushi, Shi, Judy, Mochizuki, Michiyo, Yoshikawa, Masato, Huang, Jian, Shen, Luhua, Haridas, Satyajeet, Shinde, Vaishali, Gemski, Chris, Roberts, Emily R., Ghasemi, Omid, Bazzazi, Hojjat, Menon, Saurabh, Traore, Tary, Shi, Pu, Thelen, Tennille D., Conlon, Joseph, Abu-Yousif, Adnan O., Arendt, Christopher, Shaw, Michael H., Okaniwa, Masanori
Publicado 2022