CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway

por Sanderlin, Edward J., Keenan, Melissa M., Mense, Martin, Revenko, Alexey S., Monia, Brett P., Guo, Shuling, Huang, Lulu
Publicado 2022

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

por Jiang, Tingting, Henderson, Jordana M., Coote, Kevin, Cheng, Yi, Valley, Hillary C., Zhang, Xiao-Ou, Wang, Qin, Rhym, Luke H., Cao, Yueying, Newby, Gregory A., Bihler, Hermann, Mense, Martin, Weng, Zhiping, Anderson, Daniel G., McCaffrey, Anton P., Liu, David R., Xue, Wen
Publicado 2020

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

por Montoro, Daniel T., Haber, Adam L., Biton, Moshe, Vinarsky, Vladimir, Lin, Brian, Birket, Susan, Yuan, Feng, Chen, Sijia, Leung, Hui Min, Villoria, Jorge, Rogel, Noga, Burgin, Grace, Tsankov, Alexander, Waghray, Avinash, Slyper, Michal, Waldmann, Julia, Nguyen, Lan, Dionne, Danielle, Rozenblatt-Rosen, Orit, Tata, Purushothama Rao, Mou, Hongmei, Shivaraju, Manjunatha, Bihler, Hermann, Mense, Martin, Tearney, Guillermo J., Rowe, Steven M., Engelhardt, John F., Regev, Aviv, Rajagopal, Jayaraj
Publicado 2018

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

por Sharma, Jyoti, Du, Ming, Wong, Eric, Mutyam, Venkateshwar, Li, Yao, Chen, Jianguo, Wangen, Jamie, Thrasher, Kari, Fu, Lianwu, Peng, Ning, Tang, Liping, Liu, Kaimao, Mathew, Bini, Bostwick, Robert J., Augelli-Szafran, Corinne E., Bihler, Hermann, Liang, Feng, Mahiou, Jerome, Saltz, Josef, Rab, Andras, Hong, Jeong, Sorscher, Eric J., Mendenhall, Eric M., Coppola, Candice J., Keeling, Kim M., Green, Rachel, Mense, Martin, Suto, Mark J., Rowe, Steven M., Bedwell, David M.
Publicado 2021