How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

por Xu, Yibin, Margetts, Mai B., Venugopal, Hari, Menting, John G., Kirk, Nicholas S., Croll, Tristan I., Delaine, Carlie, Forbes, Briony E., Lawrence, Michael C.
Publicado 2022

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

por van Lierop, Bianca, Ong, Shee Chee, Belgi, Alessia, Delaine, Carlie, Andrikopoulos, Sofianos, Haworth, Naomi L., Menting, John G., Lawrence, Michael C., Robinson, Andrea J., Forbes, Briony E.
Publicado 2017

The signalling conformation of the insulin receptor ectodomain

por Weis, Felix, Menting, John G., Margetts, Mai B., Chan, Shu Jin, Xu, Yibin, Tennagels, Norbert, Wohlfart, Paulus, Langer, Thomas, Müller, Christoph W., Dreyer, Matthias K., Lawrence, Michael C.
Publicado 2018

How ligand binds to the type 1 insulin-like growth factor receptor

por Xu, Yibin, Kong, Geoffrey K.-W., Menting, John G., Margetts, Mai B., Delaine, Carlie A., Jenkin, Lauren M., Kiselyov, Vladislav V., De Meyts, Pierre, Forbes, Briony E., Lawrence, Michael C.
Publicado 2018

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

por Xiong, Xiaochun, Menting, John G., Disotuar, Maria M., Smith, Nicholas A., Delaine, Carlie, Ghabash, Gabrielle, Agrawal, Rahul, Wang, Xiaomin, He, Xiao, Fisher, Simon J., MacRaild, Christopher A., Norton, Raymond S., Gajewiak, Joanna, Forbes, Briony E., Smith, Brian J., Safavi-Hemami, Helena, Olivera, Baldomero, Lawrence, Michael C., Hung-Chieh Chou, Danny
Publicado 2020

Symmetric and Asymmetric Receptor Conformation Continuum induced by a Novel Insulin

por Xiong, Xiaochun, Blakely, Alan, Kim, Jin Hwan, Menting, John G., Schäfer, Ingmar B., Schubert, Heidi L., Agrawal, Rahul, Gutmann, Theresia, Delaine, Carlie, Zhang, Yi Wolf, Artik, Gizem Olay, Merriman, Allanah, Eckert, Debbie, Lawrence, Michael C., Coskun, Ünal, Fisher, Simon J., Forbes, Briony E., Safavi-Hemami, Helena, Hill, Christopher P., Chou, Danny Hung-Chieh
Publicado 2022