Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis

por Spencer, Robert H., Munera, Catherine, Shram, Megan J., Menzaghi, Frédérique
Publicado 2023

The Burden of Pruritus Associated With CKD: A Mixed Methods Analysis Among Patients Undergoing Dialysis

por Menzaghi, Frédérique, Vernon, Margaret K., Mattera, Maria, Cirulli, Joshua, Wen, Warren, Spencer, Robert H., Munera, Catherine
Publicado 2023

Pharmacokinetics, Metabolism, and Excretion of Intravenous [14C]Difelikefalin in Healthy Subjects and Subjects on Hemodialysis

por Stark, Jeffrey G., Noonan, Patrick K., Spencer, Robert H., Bhaduri, Sarbani, O’Connor, Stephen J., Menzaghi, Frédérique
Publicado 2023

Safety and Tolerability of Difelikefalin for the Treatment of Moderate to Severe Pruritus in Hemodialysis Patients: Pooled Analysis From the Phase 3 Clinical Trial Program

por Fishbane, Steven, Wen, Warren, Munera, Catherine, Lin, Rong, Bagal, Sukirti, McCafferty, Kieran, Menzaghi, Frédérique, Goncalves, Joana
Publicado 2022

Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients

por Fishbane, Steven, Mathur, Vandana, Germain, Michael J., Shirazian, Shayan, Bhaduri, Sarbani, Munera, Catherine, Spencer, Robert H., Menzaghi, Frédérique
Publicado 2020

Psychometric validation and meaningful change thresholds of the Worst Itching Intensity Numerical Rating Scale for assessing itch in patients with chronic kidney disease-associated...

por Vernon, Margaret K., Swett, Laura L., Speck, Rebecca M., Munera, Catherine, Spencer, Robert H., Wen, Warren, Menzaghi, Frédérique
Publicado 2021

Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users

por Shram, Megan J., Spencer, Robert H., Qian, Jenny, Munera, Catherine L., Lewis, Michael E., Henningfield, Jack E., Webster, Lynn, Menzaghi, Frédérique
Publicado 2021

Safety and Effectiveness of Difelikefalin in Patients With Moderate-to-Severe Pruritus Undergoing Hemodialysis: An Open-Label, Multicenter Study

por Weiner, Daniel E., Vervloet, Marc G., Walpen, Sebastian, Schaufler, Thilo, Munera, Catherine, Menzaghi, Frédérique, Wen, Warren, Bhaduri, Sarbani, Germain, Michael J.
Publicado 2022

Utility of a Single Itch-Related Question and the Skindex-10 Questionnaire for Assessing Pruritus and Predicting Health-Related Quality of Life in Patients Receiving Hemodialysis

por Lopes, Marcelo Barreto, Karaboyas, Angelo, Sukul, Nidhi, Tsuruya, Kazuhiko, Al Salmi, Issa, Asgari, Elham, Alyousef, Anas, Schaufler, Thilo, Walpen, Sebastian, Menzaghi, Frederique, Pisoni, Ronald
Publicado 2022

Efficacy of Difelikefalin for the Treatment of Moderate to Severe Pruritus in Hemodialysis Patients: Pooled Analysis of KALM-1 and KALM-2 Phase 3 Studies

por Topf, Joel, Wooldridge, Thomas, McCafferty, Kieran, Schömig, Michael, Csiky, Botond, Zwiech, Rafal, Wen, Warren, Bhaduri, Sarbani, Munera, Catherine, Lin, Rong, Jebara, Alia, Cirulli, Joshua, Menzaghi, Frédérique
Publicado 2022

Self-reported Pruritus and Clinical, Dialysis-Related, and Patient-Reported Outcomes in Hemodialysis Patients

por Sukul, Nidhi, Karaboyas, Angelo, Csomor, Philipp A., Schaufler, Thilo, Wen, Warren, Menzaghi, Frédérique, Rayner, Hugh C., Hasegawa, Takeshi, Al Salmi, Issa, Al-Ghamdi, Saeed M.G., Guebre-Egziabher, Fitsum, Ureña-Torres, Pablo-Antonio, Pisoni, Ronald L.
Publicado 2020