The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

por Jahreiss, Luca, Menzies, Fiona M, Rubinsztein, David C
Publicado 2008

Protein misfolding disorders and macroautophagy

por Menzies, Fiona M, Moreau, Kevin, Rubinsztein, David C
Publicado 2011

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

por Korolchuk, Viktor I., Mansilla, Alicia, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2009

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3

por Menzies, Fiona M., Huebener, Jeannette, Renna, Maurizio, Bonin, Michael, Riess, Olaf, Rubinsztein, David C.
Publicado 2010

Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis

por Wu, Xiaoting, Fleming, Angeleen, Ricketts, Thomas, Pavel, Mariana, Virgin, Herbert, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2016

Leucine regulates autophagy via acetylation of the mTORC1 component raptor

por Son, Sung Min, Park, So Jung, Stamatakou, Eleanna, Vicinanza, Mariella, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2020

The Hedgehog signalling pathway regulates autophagy

por Jimenez-Sanchez, Maria, Menzies, Fiona M., Chang, Yu-Yun, Simecek, Nikol, Neufeld, Thomas P., Rubinsztein, David C.
Publicado 2012

Myc inhibition impairs autophagosome formation

por Toh, Pearl P. C., Luo, Shouqing, Menzies, Fiona M., Raskó, Tamás, Wanker, Erich E., Rubinsztein, David C.
Publicado 2013

PI(5)P Regulates Autophagosome Biogenesis

por Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Publicado 2015

Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

por Son, Sung Min, Park, So Jung, Lee, Huikyong, Siddiqi, Farah, Lee, Jong Eun, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2019

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

por Rose, Claudia, Menzies, Fiona M., Renna, Maurizio, Acevedo-Arozena, Abraham, Corrochano, Silvia, Sadiq, Oana, Brown, Steve D., Rubinsztein, David C.
Publicado 2010

The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A

por Puri, Claudia, Vicinanza, Mariella, Ashkenazi, Avraham, Gratian, Matthew J., Zhang, Qifeng, Bento, Carla F., Renna, Maurizio, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2018

Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy

por Moreau, Kevin, Ghislat, Ghita, Hochfeld, Warren, Renna, Maurizio, Zavodszky, Eszter, Runwal, Gautam, Puri, Claudia, Lee, Shirley, Siddiqi, Farah, Menzies, Fiona M., Ravikumar, Brinda, Rubinsztein, David C.
Publicado 2015

Polyglutamine tracts regulate beclin 1-dependent autophagy

por Ashkenazi, Avraham, Bento, Carla F., Ricketts, Thomas, Vicinanza, Mariella, Siddiqi, Farah, Pavel, Mariana, Squitieri, Ferdinando, Hardenberg, Maarten C., Imarisio, Sara, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2017

Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy

por Menzies, Fiona M., Hourez, Raphael, Imarisio, Sara, Raspe, Marcel, Sadiq, Oana, Chandraratna, Dhia, O'Kane, Cahir, Rock, Kenneth L., Reits, Eric, Goldberg, Alfred L., Rubinsztein, David C.
Publicado 2010

CCT complex restricts neuropathogenic protein aggregation via autophagy

por Pavel, Mariana, Imarisio, Sara, Menzies, Fiona M., Jimenez-Sanchez, Maria, Siddiqi, Farah H., Wu, Xiaoting, Renna, Maurizio, O'Kane, Cahir J., Crowther, Damian C., Rubinsztein, David C.
Publicado 2016

α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation

por Pavel, Mariana, Park, So Jung, Frake, Rebecca A., Son, Sung Min, Manni, Marco M., Bento, Carla F., Renna, Maurizio, Ricketts, Thomas, Menzies, Fiona M., Tanasa, Radu, Rubinsztein, David C.
Publicado 2021

Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis

por Pavel, Mariana, Renna, Maurizio, Park, So Jung, Menzies, Fiona M., Ricketts, Thomas, Füllgrabe, Jens, Ashkenazi, Avraham, Frake, Rebecca A., Lombarte, Alejandro Carnicer, Bento, Carla F., Franze, Kristian, Rubinsztein, David C.
Publicado 2018

Lysosomal positioning coordinates cellular nutrient responses

por Korolchuk, Viktor I., Saiki, Shinji, Lichtenberg, Maike, Siddiqi, Farah H., Roberts, Esteban A., Imarisio, Sara, Jahreiss, Luca, Sarkar, Sovan, Futter, Marie, Menzies, Fiona M., O'Kane, Cahir J., Deretic, Vojo, Rubinsztein, David C.
Publicado 2011

Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease

por Weninger, Stacie, Sperling, Bjorn, Alexander, Robert, Ivarsson, Magnus, Menzies, Fiona M., Powchik, Peter, Weber, Christopher J., Altar, C. Anthony, Crystal, Ronald G., Haggarty, Stephen J., Loring, Jeanne, Bain, Lisa J., Carrillo, Maria C.
Publicado 2020