Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability

por Menzies, Georgina E., Reed, Simon H., Brancale, Andrea, Lewis, Paul D.
Publicado 2015

A Proofreading Mutation with an Allosteric Effect Allows a Cluster of SARS-CoV-2 Viruses to Rapidly Evolve

por Mack, Andrew H, Menzies, Georgina, Southgate, Alex, Jones, D Dafydd, Connor, Thomas R
Publicado 2023

Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5

por Zelek, Wioleta M., Menzies, Georgina E., Brancale, Andrea, Stockinger, Brigitta, Morgan, Bryan Paul
Publicado 2020

Carcinogen-induced DNA structural distortion differences in the RAS gene isoforms; the importance of local sequence

por Menzies, Georgina E., Prior, Ian A., Brancale, Andrea, Reed, Simon H., Lewis, Paul D.
Publicado 2021

Age-dependent effect of APOE and polygenic component on Alzheimer's disease

por Bellou, Eftychia, Baker, Emily, Leonenko, Ganna, Bracher-Smith, Matthew, Daunt, Paula, Menzies, Georgina, Williams, Julie, Escott-Price, Valentina
Publicado 2020

Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK biobank

por Bracher-Smith, Matthew, Rees, Elliott, Menzies, Georgina, Walters, James T.R., O'Donovan, Michael C., Owen, Michael J., Kirov, George, Escott-Price, Valentina
Publicado 2022

Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank

por Dennison, Charlotte A., Legge, Sophie E., Bracher-Smith, Matthew, Menzies, Georgina, Escott-Price, Valentina, Smith, Daniel J., Doherty, Aiden R., Owen, Michael J., O’Donovan, Michael C., Walters, James T. R.
Publicado 2021

Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort

por Grama, Steluta, Willcocks, Isabella, Hubert, John J., Pardiñas, Antonio F., Legge, Sophie E., Bracher-Smith, Matthew, Menzies, Georgina E., Hall, Lynsey S., Pocklington, Andrew J., Anney, Richard J. L., Bray, Nicholas J., Escott-Price, Valentina, Caseras, Xavier
Publicado 2020

PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease‐protective variant PLCγ2 R522

por Maguire, Emily, Menzies, Georgina E, Phillips, Thomas, Sasner, Michael, Williams, Harriet M, Czubala, Magdalena A, Evans, Neil, Cope, Emma L, Sims, Rebecca, Howell, Gareth R, Lloyd‐Evans, Emyr, Williams, Julie, Allen, Nicholas D, Taylor, Philip R
Publicado 2021

Structure–Activity Relationships of Low Molecular Weight Alginate Oligosaccharide Therapy against Pseudomonas aeruginosa

por Pritchard, Manon F., Powell, Lydia C., Adams, Jennifer Y. M., Menzies, Georgina, Khan, Saira, Tøndervik, Anne, Sletta, Håvard, Aarstad, Olav, Skjåk-Bræk, Gudmund, McKenna, Stephen, Buurma, Niklaas J., Farnell, Damian J. J., Rye, Philip D., Hill, Katja E., Thomas, David W.
Publicado 2023

Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides

por Powell, Lydia C., Pritchard, Manon F., Ferguson, Elaine L., Powell, Kate A., Patel, Shree U., Rye, Phil D., Sakellakou, Stavroula-Melina, Buurma, Niklaas J., Brilliant, Charles D., Copping, Jack M., Menzies, Georgina E., Lewis, Paul D., Hill, Katja E., Thomas, David W.
Publicado 2018

Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits

por Legge, Sophie E., Jones, Hannah J., Kendall, Kimberley M., Pardiñas, Antonio F., Menzies, Georgina, Bracher-Smith, Matthew, Escott-Price, Valentina, Rees, Elliott, Davis, Katrina A. S., Hotopf, Matthew, Savage, Jeanne E., Posthuma, Danielle, Holmans, Peter, Kirov, George, Owen, Michael J., O’Donovan, Michael C., Zammit, Stanley, Walters, James T. R.
Publicado 2019

Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset

por McAllister, Branduff, Donaldson, Jasmine, Binda, Caroline S., Powell, Sophie, Chughtai, Uroosa, Edwards, Gareth, Stone, Joseph, Lobanov, Sergey, Elliston, Linda, Schuhmacher, Laura-Nadine, Rees, Elliott, Menzies, Georgina, Ciosi, Marc, Maxwell, Alastair, Chao, Michael J., Hong, Eun Pyo, Lucente, Diane, Wheeler, Vanessa, Lee, Jong-Min, MacDonald, Marcy E., Long, Jeffrey D., Aylward, Elizabeth H., Landwehrmeyer, G. Bernhard, Rosser, Anne E., Paulsen, Jane S., Williams, Nigel M., Gusella, James F., Monckton, Darren G., Allen, Nicholas D., Holmans, Peter, Jones, Lesley, Massey, Thomas H.
Publicado 2022