A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway

por Zablocki-Thomas, Laurent, Menzies, Sam A, Lehner, Paul J, Manel, Nicolas, Benaroch, Philippe
Publicado 2020

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

por Menzies, Sam A, Volkmar, Norbert, van den Boomen, Dick JH, Timms, Richard T, Dickson, Anna S, Nathan, James A, Lehner, Paul J
Publicado 2018

Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens

por Timms, Richard T., Menzies, Sam A., Tchasovnikarova, Iva A., Christensen, Lea C., Williamson, James C., Antrobus, Robin, Dougan, Gordon, Ellgaard, Lars, Lehner, Paul J.
Publicado 2016

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

por Li, Ji, Stagg, Nicola J., Johnston, Jennifer, Harris, Michael J., Menzies, Sam A., DiCara, Danielle, Clark, Vanessa, Hristopoulos, Maria, Cook, Ryan, Slaga, Dionysos, Nakamura, Rin, McCarty, Luke, Sukumaran, Siddharth, Luis, Elizabeth, Ye, Zhengmao, Wu, Thomas D., Sumiyoshi, Teiko, Danilenko, Dimitry, Lee, Genee Y., Totpal, Klara, Ellerman, Diego, Hötzel, Isidro, James, John R., Junttila, Teemu T.
Publicado 2017