Small molecule selected to disrupt oncogenic protein EWS-FLI1 interaction with RNA Helicase A inhibits Ewing's Sarcoma

por Erkizan, Hayriye V., Kong, Yali, Merchant, Melinda, Schlottmann, Silke, Barber-Rotenberg, Julie S., Abaan, Ogan D., Chou, Tsu-hang, Dakshanamurthy, Sivanesan, Brown, Milton L., Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2009

Evaluation of Combination Strategies for the A(2A)R Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model

por Voronova, Veronika, Peskov, Kirill, Kosinsky, Yuri, Helmlinger, Gabriel, Chu, Lulu, Borodovsky, Alexandra, Woessner, Richard, Sachsenmeier, Kris, Shao, Wenlin, Kumar, Rakesh, Pouliot, Gayle, Merchant, Melinda, Kimko, Holly, Mugundu, Ganesh
Publicado 2021

Optimizing engineered TCR T cell therapy for synovial sarcoma

por D'Angelo, Sandra, Merchant, Melinda, Melchiori, Luca, Zhang, Hua, Pandite, Lini, Holdich, Tom, Binder-Scholl, Gwendolyn, Tap, William, Fortin, Marylene, Peretz, Yoav, Wright, Matthew, Meyers, Paul, Amado, Rafael, Jakobsen, Bent, Mackall, Crystal
Publicado 2015

IL-7 signaling in dendritic cells regulates CD4(+) T cell homeostatic proliferation and CD4(+) T cell niche size

por Guimond, Martin, Veenstra, Rachelle G., Grindler, David J., Zhang, Hua, Cui, Yongzhi, Murphy, Ryan D., Kim, Su Young, Na, Risu, Henninghausen, Lothar, Kurtulus, Sema, Erman, Batu, Matzinger, Polly, Merchant, Melinda S., Mackall1, Crystal L.
Publicado 2009

A de novo nonsense mutation in the tyrosine kinase lyn in a patient with an early onset autoinflammatory phenotype

por De Jesus, Adriana Almeida, Montealegre, Gina, Liu, Yin, Marrero, Bernadette, Kuehn, Hyesun, Calvo, Katherine, Rosenzweig, Sergio, Fleisher, Thomas, Lee, Richard Chyi-Chia, Brundidge, April, Chapelle, Dawn, Huang, Yan, Brooks, Stephen, Moir, Susan, Meffre, Eric, Merchant, Melinda, Deng, Zuoming, Goldbach-Mansky, Raphaela
Publicado 2014

Feasibility of implementing molecular-guided therapy for the treatment of patients with relapsed or refractory neuroblastoma

por Saulnier Sholler, Giselle L, Bond, Jeffrey P, Bergendahl, Genevieve, Dutta, Akshita, Dragon, Julie, Neville, Kathleen, Ferguson, William, Roberts, William, Eslin, Don, Kraveka, Jacqueline, Kaplan, Joel, Mitchell, Deanna, Parikh, Nehal, Merchant, Melinda, Ashikaga, Takamaru, Hanna, Gina, Lescault, Pamela Jean, Siniard, Ashley, Corneveaux, Jason, Huentelman, Matthew, Trent, Jeffrey
Publicado 2015

Challenges to curing primary brain tumours

por Aldape, Kenneth, Brindle, Kevin M., Chesler, Louis, Chopra, Rajesh, Gajjar, Amar, Gilbert, Mark R., Gottardo, Nicholas, Gutmann, David H., Hargrave, Darren, Holland, Eric C., Jones, David T. W., Joyce, Johanna A., Kearns, Pamela, Kieran, Mark W., Mellinghoff, Ingo K., Merchant, Melinda, Pfister, Stefan M., Pollard, Steven M., Ramaswamy, Vijay, Rich, Jeremy N., Robinson, Giles W., Rowitch, David H., Sampson, John H., Taylor, Michael D., Workman, Paul, Gilbertson, Richard J.
Publicado 2019

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome

por de Jesus, Adriana A., Chen, Guibin, Yang, Dan, Brdicka, Tomas, Ruth, Natasha M., Bennin, David, Cebecauerova, Dita, Malcova, Hana, Freeman, Helen, Martin, Neil, Svojgr, Karel, Passo, Murray H., Bhuyan, Farzana, Alehashemi, Sara, Rastegar, Andre T., Uss, Katsiaryna, Kardava, Lela, Marrero, Bernadette, Duric, Iris, Omoyinmi, Ebun, Peldova, Petra, Lee, Chyi-Chia Richard, Kleiner, David E., Hadigan, Colleen M., Hewitt, Stephen M., Pittaluga, Stefania, Carmona-Rivera, Carmelo, Calvo, Katherine R., Shah, Nirali, Balascakova, Miroslava, Fink, Danielle L., Kotalova, Radana, Parackova, Zuzana, Peterkova, Lucie, Kuzilkova, Daniela, Campr, Vit, Sramkova, Lucie, Biancotto, Angelique, Brooks, Stephen R., Manes, Cameron, Meffre, Eric, Harper, Rebecca L., Kuehn, Hyesun, Kaplan, Mariana J., Brogan, Paul, Rosenzweig, Sergio D., Merchant, Melinda, Deng, Zuoming, Huttenlocher, Anna, Moir, Susan L., Kuhns, Douglas B., Boehm, Manfred, Skvarova Kramarzova, Karolina, Goldbach-Mansky, Raphaela
Publicado 2023