Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention

por Mercher, Thomas, Schwaller, Juerg
Publicado 2019

Corrigendum: Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention

por Mercher, Thomas, Schwaller, Juerg
Publicado 2019

Molecular Landscapes and Models of Acute Erythroleukemia

por Fagnan, Alexandre, Piqué-Borràs, Maria-Riera, Tauchmann, Samantha, Mercher, Thomas, Schwaller, Juerg
Publicado 2021

JAM-C/Jam-C Expression Is Primarily Expressed in Mouse Hematopoietic Stem Cells

por Henry, Elia, Barroca, Vilma, Lopez, Cécile K., Aurrand-Lions, Michel, Lewandowski, Daniel, Mercher, Thomas, Arcangeli, Marie-Laure
Publicado 2021

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

por Babin, Loelia, Piganeau, Marion, Renouf, Benjamin, Lamribet, Khadija, Thirant, Cecile, Deriano, Ludovic, Mercher, Thomas, Giovannangeli, Carine, Brunet, Erika C.
Publicado 2018

Recurrent TET2 mutations in adult T cell leukemia

por Marçais, Ambroise, Hanssens, Katia, Cook, Lucy, Mercher, Thomas, Gaulard, Philippe, Asnafi, Vahid, Pique, Claudine, Bazarbachi, Ali, Suarez, Felipe, Bernard, Olivier, Bangham, Charles RM, Dubreuil, Patrice, Hermine, Olivier
Publicado 2014

SPEN integrates transcriptional and epigenetic control of X-inactivation

por Dossin, François, Pinheiro, Inês, Żylicz, Jan J., Roensch, Julia, Collombet, Samuel, Le Saux, Agnès, Chelmicki, Tomasz, Attia, Mikaël, Kapoor, Varun, Zhan, Ye, Dingli, Florent, Loew, Damarys, Mercher, Thomas, Dekker, Job, Heard, Edith
Publicado 2020

Nfkbie-deficiency leads to increased susceptibility to develop B-cell lymphoproliferative disorders in aged mice

por Della-Valle, Veronique, Roos-Weil, Damien, Scourzic, Laurianne, Mouly, Enguerran, Aid, Zakia, Darwiche, Walaa, Lecluse, Yann, Damm, Frederik, Mémet, Sylvie, Mercher, Thomas, Aoufouchi, Said, Nguyen-Khac, Florence, Bernard, Olivier A., Ghamlouch, Hussein
Publicado 2020

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia

por Leonards, Katharina, Almosailleakh, Marwa, Tauchmann, Samantha, Bagger, Frederik Otzen, Thirant, Cécile, Juge, Sabine, Bock, Thomas, Méreau, Hélène, Bezerra, Matheus F., Tzankov, Alexandar, Ivanek, Robert, Losson, Régine, Peters, Antoine H. F. M., Mercher, Thomas, Schwaller, Juerg
Publicado 2020

The Pediatric Acute Leukemia Fusion Oncogene ETO2-GLIS2 Increases Self-Renewal and Alters Differentiation in a Human Induced Pluripotent Stem Cells-Derived Model

por Bertuccio, Salvatore Nicola, Boudia, Fabien, Cambot, Marie, Lopez, Cécile K., Lordier, Larissa, Donada, Alessandro, Robert, Elie, Thirant, Cécile, Aid, Zakia, Serravalle, Salvatore, Astolfi, Annalisa, Indio, Valentina, Locatelli, Franco, Pession, Andrea, Vainchenker, William, Masetti, Riccardo, Raslova, Hana, Mercher, Thomas
Publicado 2019

The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

por Piqué-Borràs, Maria-Riera, Jevtic, Zivojin, Bagger, Frederik Otzen, Seguin, Jonathan, Sivalingam, Rathick, Bezerra, Matheus Filgueira, Louwagie, Amber, Juge, Sabine, Nellas, Ioannis, Ivanek, Robert, Tzankov, Alexandar, Moll, Ute M., Cantillo, Oriano, Schulz-Heddergott, Ramona, Fagnan, Alexandre, Mercher, Thomas, Schwaller, Juerg
Publicado 2023

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

por Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François
Publicado 2013

Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia

por Benbarche, Salima, Lopez, Cécile K., Salataj, Eralda, Aid, Zakia, Thirant, Cécile, Laiguillon, Marie-Charlotte, Lecourt, Séverine, Belloucif, Yannis, Vaganay, Camille, Antonini, Marion, Hu, Jiang, da Silva Babinet, Alexandra, Ndiaye-Lobry, Delphine, Pardieu, Bryann, Petit, Arnaud, Puissant, Alexandre, Chaumeil, Julie, Mercher, Thomas, Lobry, Camille
Publicado 2022

MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia

por Pikman, Yana, Lee, Benjamin H, Mercher, Thomas, McDowell, Elizabeth, Ebert, Benjamin L, Gozo, Maricel, Cuker, Adam, Wernig, Gerlinde, Moore, Sandra, Galinsky, Ilene, DeAngelo, Daniel J, Clark, Jennifer J, Lee, Stephanie J, Golub, Todd R, Wadleigh, Martha, Gilliland, D. Gary, Levine, Ross L
Publicado 2006

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

por Babin, Loélia, Darchen, Alice, Robert, Elie, Aid, Zakia, Borry, Rosalie, Soudais, Claire, Piganeau, Marion, De Cian, Anne, Giovannangeli, Carine, Bawa, Olivia, Rigaud, Charlotte, Scoazec, Jean-Yves, Couronné, Lucile, Veleanu, Layla, Cieslak, Agata, Asnafi, Vahid, Sibon, David, Lamant, Laurence, Meggetto, Fabienne, Mercher, Thomas, Brunet, Erika
Publicado 2022

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

por Scourzic, Laurianne, Couronné, Lucile, Pedersen, Marianne T., Della Valle, Véronique, Diop, M’boyba, Mylonas, Elena, Calvo, Julien, Mouly, Enguerran, Lopez, Cécile K., Martin, Nadine, Fontenay, Michaëla, Bender, Ambre, Guibert, Sylvain, Dubreuil, Patrice, Dessen, Philippe, Droin, Nathalie, Pflumio, Françoise, Weber, Michael, Gaulard, Philippe, Helin, Kristian, Mercher, Thomas, Bernard, Olivier A.
Publicado 2016

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model

por Arkoun, Brahim, Robert, Elie, Boudia, Fabien, Mazzi, Stefania, Dufour, Virginie, Siret, Aurélie, Mammasse, Yasmine, Aid, Zakia, Vieira, Matthieu, Imanci, Aygun, Aglave, Marine, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Hermine, Olivier, Droin, Nathalie, Debili, Najet, Plo, Isabelle, Malinge, Sébastien, Soler, Eric, Raslova, Hana, Mercher, Thomas, Vainchenker, William
Publicado 2022

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

por Thiollier, Clarisse, Lopez, Cécile K., Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M’Boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D., Ballerini, Paola, Bernard, Olivier A., Pflumio, Françoise, Mercher, Thomas
Publicado 2012

A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

por Marques Da Costa, Maria Eugénia, Zaidi, Sakina, Scoazec, Jean-Yves, Droit, Robin, Lim, Wan Ching, Marchais, Antonin, Salmon, Jerome, Cherkaoui, Sarah, Morscher, Raphael J., Laurent, Anouchka, Malinge, Sébastien, Mercher, Thomas, Tabone-Eglinger, Séverine, Goddard, Isabelle, Pflumio, Francoise, Calvo, Julien, Redini, Francoise, Entz-Werlé, Natacha, Soriano, Aroa, Villanueva, Alberto, Cairo, Stefano, Chastagner, Pascal, Moro, Massimo, Owens, Cormac, Casanova, Michela, Hladun-Alvaro, Raquel, Berlanga, Pablo, Daudigeos-Dubus, Estelle, Dessen, Philippe, Zitvogel, Laurence, Lacroix, Ludovic, Pierron, Gaelle, Delattre, Olivier, Schleiermacher, Gudrun, Surdez, Didier, Geoerger, Birgit
Publicado 2023