Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1(STEM) Mouse

por Mercier, Francois E., Sykes, David B., Scadden, David T.
Publicado 2016

Identification of a Reliable Biomarker Profile for the Diagnosis of Gaucher Disease Type 1 Patients Using a Mass Spectrometry-Based Metabolomic Approach

por Menkovic, Iskren, Boutin, Michel, Alayoubi, Abdulfatah, Mercier, François E., Rivard, Georges-Étienne, Auray-Blais, Christiane
Publicado 2020

Recent Advances in Cancer Drug Discovery Through the Use of Phenotypic Reporter Systems, Connectivity Mapping, and Pooled CRISPR Screening

por Salame, Natasha, Fooks, Katharine, El-Hachem, Nehme, Bikorimana, Jean-Pierre, Mercier, François E., Rafei, Moutih
Publicado 2022

Quantitation of a Urinary Profile of Biomarkers in Gaucher Disease Type 1 Patients Using Tandem Mass Spectrometry

por Menkovic, Iskren, Boutin, Michel, Alayoubi, Abdulfatah, Curado, Filipa, Bauer, Peter, Mercier, François E., Auray-Blais, Christiane
Publicado 2022

PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

por Maru, Bruktawit, Messikommer, Alessandra, Huang, Linhui, Seipel, Katja, Kovecses, Olivia, Valk, Peter J.M., Theocharides, Alexandre P.A., Mercier, Francois E., Pabst, Thomas, McKeague, Maureen, Luedtke, Nathan W.
Publicado 2023

Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant

por Bazinet, Alexandre, Heath, John, Chong, Anne-Sophie, Simo-Cheyou, Estelle R., Worme, Samantha, Rivera Polo, Barbara, Foulkes, William D., Caplan, Stephen, Johnson, Nathalie A., Orthwein, Alexandre, Mercier, François E.
Publicado 2021

In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies

por Mercier, Francois E., Shi, Jiantao, Sykes, David B., Oki, Toshihiko, Jankovic, Maja, Man, Cheuk Him, Kfoury, Youmna S., Miller, Elizabeth, He, Shutao, Zhu, Alexander, Vasic, Radovan, Doench, John, Orthwein, Alexandre, Michor, Franziska, Scadden, David T.
Publicado 2022

EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax

por Fooks, Katie, Galicia-Vazquez, Gabriela, Gife, Victor, Schcolnik-Cabrera, Alejandro, Nouhi, Zaynab, Poon, William W. L., Luo, Vincent, Rys, Ryan N., Aloyz, Raquel, Orthwein, Alexandre, Johnson, Nathalie A., Hulea, Laura, Mercier, Francois E.
Publicado 2022

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

por Almeida, Francisca F., Tognarelli, Sara, Marçais, Antoine, Kueh, Andrew J., Friede, Miriam E., Liao, Yang, Willis, Simon N., Luong, Kylie, Faure, Fabrice, Mercier, Francois E., Galluso, Justine, Firth, Matthew, Narni-Mancinelli, Emilie, Rais, Bushra, Scadden, David T., Spallotta, Francesco, Weil, Sandra, Giannattasio, Ariane, Kalensee, Franziska, Zöller, Tobias, Huntington, Nicholas D., Schleicher, Ulrike, Chiocchetti, Andreas G., Ugolini, Sophie, Herold, Marco J., Shi, Wei, Koch, Joachim, Steinle, Alexander, Vivier, Eric, Walzer, Thierry, Belz, Gabrielle T., Ullrich, Evelyn
Publicado 2018