Viral burden, inflammatory milieu and CD8(+) T‐cell responses to influenza virus in a second‐generation thiazolide (RM‐5061) and oseltamivir combination therapy study

por Nüssing, Simone, Mifsud, Edin, Hensen, Luca, Koutsakos, Marios, Wang, Zhongfang, Kedzierski, Lukasz, Mercuri, Francesca, Rossignol, Jean‐Francois, Hurt, Aeron C., Kedzierska, Katherine
Publicado 2020

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

por Chua, Brendon Y., Wong, Chinn Yi, Mifsud, Edin J., Edenborough, Kathryn M., Sekiya, Toshiki, Tan, Amabel C. L., Mercuri, Francesca, Rockman, Steve, Chen, Weisan, Turner, Stephen J., Doherty, Peter C., Kelso, Anne, Brown, Lorena E., Jackson, David C.
Publicado 2015

TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs

por Deliyannis, Georgia, Wong, Chinn Yi, McQuilten, Hayley A., Bachem, Annabell, Clarke, Michele, Jia, Xiaoxiao, Horrocks, Kylie, Zeng, Weiguang, Girkin, Jason, Scott, Nichollas E., Londrigan, Sarah L., Reading, Patrick C., Bartlett, Nathan W., Kedzierska, Katherine, Brown, Lorena E., Mercuri, Francesca, Demaison, Christophe, Jackson, David C., Chua, Brendon Y.
Publicado 2021

Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

por Proud, Pamela C., Tsitoura, Daphne, Watson, Robert J., Chua, Brendon Y., Aram, Marilyn J., Bewley, Kevin R., Cavell, Breeze E., Cobb, Rebecca, Dowall, Stuart, Fotheringham, Susan A., Ho, Catherine M.K., Lucas, Vanessa, Ngabo, Didier, Rayner, Emma, Ryan, Kathryn A., Slack, Gillian S., Thomas, Stephen, Wand, Nadina I., Yeates, Paul, Demaison, Christophe, Zeng, Weiguang, Holmes, Ian, Jackson, David C., Bartlett, Nathan W., Mercuri, Francesca, Carroll, Miles W.
Publicado 2020