Immunotherapy and the belly of the beast

por Merghoub, Taha, Wolchok, Jedd D.
Publicado 2014

Direct comparisons of T cell costimulation and checkpoint blockade in the setting of tumor-targeted monoclonal antibody therapy

por Khalil, Danny, Merghoub, Taha, Wolchok, Jedd
Publicado 2015

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer

por Dermime, Said, Merhi, Maysaloun, Merghoub, Taha
Publicado 2021

Myeloid-derived suppressor cells and the efficacy of CD8(+) T-cell immunotherapy

por Lesokhin, Alexander M., Merghoub, Taha, Wolchok, Jedd D.
Publicado 2013

Innate immune checkpoints for cancer immunotherapy: expanding the scope of non T cell targets

por Campesato, Luis F., Weng, Chien-Huan, Merghoub, Taha
Publicado 2020

Targeted APC Activation in Cancer Immunotherapy to Enhance the Abscopal Effect

por Suek, Nathan, Campesato, Luis Felipe, Merghoub, Taha, Khalil, Danny N.
Publicado 2019

Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressi...

por Holmgaard, Rikke B., Zamarin, Dmitriy, Lesokhin, Alexander, Merghoub, Taha, Wolchok, Jedd D.
Publicado 2016

35336 Effect of Nuclear Soluble Adenylyl Cyclase (sAC) on Melanoma Treatment Response

por Bang, Jakyung, Drozdz, Marek M., Dong, Lauren, Merghoub, Taha, Zippin, Jonathan H.
Publicado 2021

Expression of indoleamine 2.3-dioxygenase by tumors induces local and systemic immunosuppressive effects in a murine melanoma model

por Holmgaard, Rikke B, Zamarin, Dmitriy, Munn, David H, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Blockade of Treg derived TGF-β abrogates suppression of effector T cell function within the tumor microenvironment

por Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd
Publicado 2013

Potentiation of immunomodulatory antibodies with oncolytic viruses for therapy of poorly-immunogenic tumors

por Zamarin, Dmitriy, Holmgaard, Rikke B, Plitt, Tamar, Allison, James, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Blockade of surface bound TGF-β abrogates Treg suppression of effector T cell function within the tumor microenvironment

por Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Impairment of Treg suppression by GITR ligation is effective selectively in the context of a pro-inflammatory tumor microenvironment

por Zappasodi, Roberta, Budhu, Sadna, Schaer, David, Yang, Xia, Zhong, Hong, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant

por Yang, Ning, Garcia, Aitor, Meyer, Cindy, Tuschl, Thomas, Merghoub, Taha, Wolchok, Jedd D., Deng, Liang
Publicado 2022

Immune-Active Microenvironment in Small Cell Carcinoma of the Ovary, Hypercalcemic Type: Rationale for Immune Checkpoint Blockade

por Jelinic, Petar, Ricca, Jacob, Van Oudenhove, Elke, Olvera, Narciso, Merghoub, Taha, Levine, Douglas A, Zamarin, Dmitriy
Publicado 2018

Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection

por Zamarin, Dmitriy, Holmgaard, Rikke, Subudhi, Sumit, Mansour, Mena, Palese, Peter, Merghoub, Taha, Wolchok, Jedd D, Allison, James P
Publicado 2013

Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy

por Ricca, Jacob M., Oseledchyk, Anton, Walther, Tyler, Liu, Cailian, Mangarin, Levi, Merghoub, Taha, Wolchok, Jedd D., Zamarin, Dmitriy
Publicado 2018

Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia

por Wang, Weiyi, Liu, Shuaitong, Dai, Peihong, Yang, Ning, Wang, Yi, Giese, Rachel A, Merghoub, Taha, Wolchok, Jedd, Deng, Liang
Publicado 2021

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

por Maus, Marcela V, Plotkin, Jason, Jakka, Gopinadh, Stewart-Jones, Guillaume, Rivière, Isabelle, Merghoub, Taha, Wolchok, Jedd, Renner, Christoph, Sadelain, Michel
Publicado 2017

Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity

por Zamarin, Dmitriy, Holmgaard, Rikke B., Ricca, Jacob, Plitt, Tamar, Palese, Peter, Sharma, Padmanee, Merghoub, Taha, Wolchok, Jedd D., Allison, James P.
Publicado 2017