Experimental and Bioinformatic Approaches to Studying DNA Methylation in Cancer

por Merkel, Angelika, Esteller, Manel
Publicado 2022

Detecting Microsatellites in Genome Data: Variance in Definitions and Bioinformatic Approaches Cause Systematic Bias

por Merkel, Angelika, Gemmell, Neil J.
Publicado 2008

Grape RNA-Seq analysis pipeline environment

por Knowles, David G., Röder, Maik, Merkel, Angelika, Guigó, Roderic
Publicado 2013

Refinement of computational identification of somatic copy number alterations using DNA methylation microarrays illustrated in cancers of unknown primary

por Blecua, Pedro, Davalos, Veronica, de Villasante, Izar, Merkel, Angelika, Musulen, Eva, Coll-SanMartin, Laia, Esteller, Manel
Publicado 2022

Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients

por Fernández-Santiago, Rubén, Merkel, Angelika, Castellano, Giancarlo, Heath, Simon, Raya, Ángel, Tolosa, Eduard, Martí, María-José, Consiglio, Antonella, Ezquerra, Mario
Publicado 2019

Global Impairment of Immediate-Early Genes Expression in Rett Syndrome Models and Patients Linked to Myelination Defects

por Petazzi, Paolo, Jorge-Torres, Olga Caridad, Gomez, Antonio, Scognamiglio, Iolanda, Serra-Musach, Jordi, Merkel, Angelika, Grases, Daniela, Xiol, Clara, O’Callaghan, Mar, Armstrong, Judith, Esteller, Manel, Guil, Sonia
Publicado 2023

Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage R...

por Cristalli, Camilla, Manara, Maria Cristina, Valente, Sergio, Pellegrini, Evelin, Bavelloni, Alberto, De Feo, Alessandra, Blalock, William, Di Bello, Elisabetta, Piñeyro, David, Merkel, Angelika, Esteller, Manel, Tirado, Oscar M., Mai, Antonello, Scotlandi, Katia
Publicado 2022

Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture

por Hernandez, Inmaculada, Dhiman, Heena, Klanert, Gerald, Jadhav, Vaibhav, Auer, Norbert, Hanscho, Michael, Baumann, Martina, Esteve‐Codina, Anna, Dabad, Marc, Gómez, Jessica, Alioto, Tyler, Merkel, Angelika, Raineri, Emanuele, Heath, Simon, Rico, Daniel, Borth, Nicole
Publicado 2019

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time

por Feichtinger, Julia, Hernández, Inmaculada, Fischer, Christoph, Hanscho, Michael, Auer, Norbert, Hackl, Matthias, Jadhav, Vaibhav, Baumann, Martina, Krempl, Peter M., Schmidl, Christian, Farlik, Matthias, Schuster, Michael, Merkel, Angelika, Sommer, Andreas, Heath, Simon, Rico, Daniel, Bock, Christoph, Thallinger, Gerhard G., Borth, Nicole
Publicado 2016

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

por Schuyler, Ronald P., Merkel, Angelika, Raineri, Emanuele, Altucci, Lucia, Vellenga, Edo, Martens, Joost H.A., Pourfarzad, Farzin, Kuijpers, Taco W., Burden, Frances, Farrow, Samantha, Downes, Kate, Ouwehand, Willem H., Clarke, Laura, Datta, Avik, Lowy, Ernesto, Flicek, Paul, Frontini, Mattia, Stunnenberg, Hendrik G., Martín-Subero, José I., Gut, Ivo, Heath, Simon
Publicado 2016

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

por Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O., Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L., Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G., Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W., Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S.
Publicado 2017

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

por Derrien, Thomas, Johnson, Rory, Bussotti, Giovanni, Tanzer, Andrea, Djebali, Sarah, Tilgner, Hagen, Guernec, Gregory, Martin, David, Merkel, Angelika, Knowles, David G., Lagarde, Julien, Veeravalli, Lavanya, Ruan, Xiaoan, Ruan, Yijun, Lassmann, Timo, Carninci, Piero, Brown, James B., Lipovich, Leonard, Gonzalez, Jose M., Thomas, Mark, Davis, Carrie A., Shiekhattar, Ramin, Gingeras, Thomas R., Hubbard, Tim J., Notredame, Cedric, Harrow, Jennifer, Guigó, Roderic
Publicado 2012

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

por Yi, Guoqiang, Wierenga, Albertus T.J., Petraglia, Francesca, Narang, Pankaj, Janssen-Megens, Eva M., Mandoli, Amit, Merkel, Angelika, Berentsen, Kim, Kim, Bowon, Matarese, Filomena, Singh, Abhishek A., Habibi, Ehsan, Prange, Koen H.M., Mulder, André B., Jansen, Joop H., Clarke, Laura, Heath, Simon, van der Reijden, Bert A., Flicek, Paul, Yaspo, Marie-Laure, Gut, Ivo, Bock, Christoph, Schuringa, Jan Jacob, Altucci, Lucia, Vellenga, Edo, Stunnenberg, Hendrik G., Martens, Joost H.A.
Publicado 2019

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

por Grassi, Luigi, Pourfarzad, Farzin, Ullrich, Sebastian, Merkel, Angelika, Were, Felipe, Carrillo-de-Santa-Pau, Enrique, Yi, Guoqiang, Hiemstra, Ida H., Tool, Anton T.J., Mul, Erik, Perner, Juliane, Janssen-Megens, Eva, Berentsen, Kim, Kerstens, Hinri, Habibi, Ehsan, Gut, Marta, Yaspo, Marie Laure, Linser, Matthias, Lowy, Ernesto, Datta, Avik, Clarke, Laura, Flicek, Paul, Vingron, Martin, Roos, Dirk, van den Berg, Timo K., Heath, Simon, Rico, Daniel, Frontini, Mattia, Kostadima, Myrto, Gut, Ivo, Valencia, Alfonso, Ouwehand, Willem H., Stunnenberg, Hendrik G., Martens, Joost H.A., Kuijpers, Taco W.
Publicado 2018

METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer

por García-Vílchez, Raquel, Añazco-Guenkova, Ana M., Dietmann, Sabine, López, Judith, Morón-Calvente, Virginia, D’Ambrosi, Silvia, Nombela, Paz, Zamacola, Kepa, Mendizabal, Isabel, García-Longarte, Saioa, Zabala-Letona, Amaia, Astobiza, Ianire, Fernández, Sonia, Paniagua, Alejandro, Miguel-López, Borja, Marchand, Virginie, Alonso-López, Diego, Merkel, Angelika, García-Tuñón, Ignacio, Ugalde-Olano, Aitziber, Loizaga-Iriarte, Ana, Lacasa-Viscasillas, Isabel, Unda, Miguel, Azkargorta, Mikel, Elortza, Félix, Bárcena, Laura, Gonzalez-Lopez, Monika, Aransay, Ana M., Di Domenico, Tomás, Sánchez-Martín, Manuel A., De Las Rivas, Javier, Guil, Sònia, Motorin, Yuri, Helm, Mark, Pandolfi, Pier Paolo, Carracedo, Arkaitz, Blanco, Sandra
Publicado 2023

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

por Agirre, Xabier, Castellano, Giancarlo, Pascual, Marien, Heath, Simon, Kulis, Marta, Segura, Victor, Bergmann, Anke, Esteve, Anna, Merkel, Angelika, Raineri, Emanuele, Agueda, Lidia, Blanc, Julie, Richardson, David, Clarke, Laura, Datta, Avik, Russiñol, Nuria, Queirós, Ana C., Beekman, Renée, Rodríguez-Madoz, Juan R., José-Enériz, Edurne San, Fang, Fang, Gutiérrez, Norma C., García-Verdugo, José M., Robson, Michael I., Schirmer, Eric C., Guruceaga, Elisabeth, Martens, Joost H.A., Gut, Marta, Calasanz, Maria J., Flicek, Paul, Siebert, Reiner, Campo, Elías, Miguel, Jesús F. San, Melnick, Ari, Stunnenberg, Hendrik G., Gut, Ivo G., Prosper, Felipe, Martín-Subero, José I.
Publicado 2015

Landscape of transcription in human cells

por Djebali, Sarah, Davis, Carrie A., Merkel, Angelika, Dobin, Alex, Lassmann, Timo, Mortazavi, Ali M., Tanzer, Andrea, Lagarde, Julien, Lin, Wei, Schlesinger, Felix, Xue, Chenghai, Marinov, Georgi K., Khatun, Jainab, Williams, Brian A., Zaleski, Chris, Rozowsky, Joel, Röder, Maik, Kokocinski, Felix, Abdelhamid, Rehab F., Alioto, Tyler, Antoshechkin, Igor, Baer, Michael T., Bar, Nadav S., Batut, Philippe, Bell, Kimberly, Bell, Ian, Chakrabortty, Sudipto, Chen, Xian, Chrast, Jacqueline, Curado, Joao, Derrien, Thomas, Drenkow, Jorg, Dumais, Erica, Dumais, Jacqueline, Duttagupta, Radha, Falconnet, Emilie, Fastuca, Meagan, Fejes-Toth, Kata, Ferreira, Pedro, Foissac, Sylvain, Fullwood, Melissa J., Gao, Hui, Gonzalez, David, Gordon, Assaf, Gunawardena, Harsha, Howald, Cedric, Jha, Sonali, Johnson, Rory, Kapranov, Philipp, King, Brandon, Kingswood, Colin, Luo, Oscar J., Park, Eddie, Persaud, Kimberly, Preall, Jonathan B., Ribeca, Paolo, Risk, Brian, Robyr, Daniel, Sammeth, Michael, Schaffer, Lorian, See, Lei-Hoon, Shahab, Atif, Skancke, Jorgen, Suzuki, Ana Maria, Takahashi, Hazuki, Tilgner, Hagen, Trout, Diane, Walters, Nathalie, Wang, Huaien, Wrobel, John, Yu, Yanbao, Ruan, Xiaoan, Hayashizaki, Yoshihide, Harrow, Jennifer, Gerstein, Mark, Hubbard, Tim, Reymond, Alexandre, Antonarakis, Stylianos E., Hannon, Gregory, Giddings, Morgan C., Ruan, Yijun, Wold, Barbara, Carninci, Piero, Guigó, Roderic, Gingeras, Thomas R.
Publicado 2012