Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy

por Messer, Andrew E., Marston, Steven B.
Publicado 2014

Myopathy-inducing mutation H40Y in ACTA1 hampers actin filament structure and function

por Chan, Chun, Fan, Jun, Messer, Andrew E., Marston, Steve B., Iwamoto, Hiroyuki, Ochala, Julien
Publicado 2016

Investigations into the Sarcomeric Protein and Ca(2+)-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus)

por Messer, Andrew E., Chan, Jasmine, Daley, Alex, Copeland, O'Neal, Marston, Steven B., Connolly, David J.
Publicado 2017

The Dilated Cardiomyopathy-Causing Mutation ACTC E361G in Cardiac Muscle Myofibrils Specifically Abolishes Modulation of Ca(2+) Regulation by Phosphorylation of Troponin I

por Vikhorev, Petr G., Song, Weihua, Wilkinson, Ross, Copeland, O’Neal, Messer, Andrew E., Ferenczi, Michael A., Marston, Steven B.
Publicado 2014

Molecular Defects in Cardiac Myofilament Ca(2+)-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin

por Sheehan, Alice, Messer, Andrew E., Papadaki, Maria, Choudhry, Afnan, Kren, Vladimír, Biedermann, David, Blagg, Brian, Khandelwal, Anuj, Marston, Steven B.
Publicado 2018

OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency

por Marston, Steven, Montgiraud, Cecile, Munster, Alex B., Copeland, O’Neal, Choi, Onjee, dos Remedios, Cristobal, Messer, Andrew E., Ehler, Elisabeth, Knöll, Ralph
Publicado 2015

Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation()

por Messer, Andrew E., Bayliss, Christopher R., El-Mezgueldi, Mohammed, Redwood, Charles S., Ward, Douglas G., Leung, Man-Ching, Papadaki, Maria, dos Remedios, Cristobal, Marston, Steven B.
Publicado 2016

The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy

por Jacques, Adam M., Briceno, Natalia, Messer, Andrew E., Gallon, Clare E., Jalilzadeh, Shapour, Garcia, Edwin, Kikonda-Kanda, Gaelle, Goddard, Jennifer, Harding, Sian E., Watkins, Hugh, Esteban, M. Tomé, Tsang, Victor T., McKenna, William J., Marston, Steven B.
Publicado 2008

Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes

por Vikhorev, Petr G., Smoktunowicz, Natalia, Munster, Alex B., Copeland, O’Neal, Kostin, Sawa, Montgiraud, Cecile, Messer, Andrew E., Toliat, Mohammad R., Li, Amy, dos Remedios, Cristobal G., Lal, Sean, Blair, Cheavar A., Campbell, Kenneth S., Guglin, Maya, Richter, Manfred, Knöll, Ralph, Marston, Steven B.
Publicado 2017

Author Correction: Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes

por Vikhorev, Petr G., Smoktunowicz, Natalia, Munster, Alex B., Copeland, O’ Neal, Kostin, Sawa, Montgiraud, Cecile, Messer, Andrew E., Toliat, Mohammad R., Li, Amy, dos Remedios, Cristobal G., Lal, Sean, Blair, Cheavar A., Campbell, Kenneth S., Guglin, Maya, Richter, Manfred, Knöll, Ralph, Marston, Steven B.
Publicado 2018