Introduction: what are the issues in addressing the allergenic potential of genetically modified foods?

por Metcalfe, Dean D
Publicado 2003

Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition

por Kirshenbaum, Arnold S, Swindle, Emily, Kulka, Marianna, Wu, Yalin, Metcalfe, Dean D
Publicado 2008

S1P(4) Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells

por Kulinski, Joseph M., Proia, Richard L., Larson, Elisabeth M., Metcalfe, Dean D., Olivera, Ana
Publicado 2018

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling

por Cruse, Glenn, Beaven, Michael A., Music, Stephen C., Bradding, Peter, Gilfillan, Alasdair M., Metcalfe, Dean D.
Publicado 2015

Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells

por Kim, Do-Kyun, Cho, Young-Eun, Song, Byoung-Joon, Kawamoto, Toshihiro, Metcalfe, Dean D., Olivera, Ana
Publicado 2019

Harnessing the Anti-Tumor Mediators in Mast Cells as a New Strategy for Adoptive Cell Transfer for Cancer

por Fereydouni, Mohammad, Motaghed, Mona, Ahani, Elnaz, Kafri, Tal, Dellinger, Kristen, Metcalfe, Dean D., Kepley, Christopher L.
Publicado 2022

Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency

por Komarow, Hirsh D., Sokolic, Robert, Hershfield, Michael S., Kohn, Donald B., Young, Michael, Metcalfe, Dean D., Candotti, Fabio
Publicado 2015

CRISPR/Cas9-engineering of HMC-1.2 cells renders a human mast cell line with a single D816V-KIT mutation: An improved preclinical model for research on mastocytosis

por Bandara, Geethani, Falduto, Guido H., Luker, Andrea, Bai, Yun, Pfeiffer, Annika, Lack, Justin, Metcalfe, Dean D., Olivera, Ana
Publicado 2023

Selective immunocapture reveals neoplastic human mast cells secrete distinct microvesicle‐ and exosome‐like populations of KIT‐containing extracellular vesicles

por Pfeiffer, Annika, Petersen, Jennifer D., Falduto, Guido H., Anderson, David Eric, Zimmerberg, Joshua, Metcalfe, Dean D., Olivera, Ana
Publicado 2022

Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT

por Bandara, Geethani, Muñoz-Cano, Rosa, Tobío, Araceli, Yin, Yuzhi, Komarow, Hirsh D., Desai, Avanti, Metcalfe, Dean D., Olivera, Ana
Publicado 2018

Assessment of low immunoglobulin levels and clinical manifestations in patients with mastocytosis

por Makovoz, Ayelet, Cousins, Kimberley L., Dominguez Aldama, Luisa N., Bolan, Hyejeong, Metcalfe, Dean D., Komarow, Hirsh D., Carter, Melody C.
Publicado 2022

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia

por Le, Quang T., Lyons, Jonathan J., Naranjo, Andrea N., Olivera, Ana, Lazarus, Robert A., Metcalfe, Dean D., Milner, Joshua D., Schwartz, Lawrence B.
Publicado 2019

Challenges in applying diagnostic criteria for systemic mastocytosis

por Boggs, Nathan A., Sun, Xiaoping, Lyons, Jonathan J., McMurray, Jeremy C., Rose, David M., Pryor, Eric M., Metcalfe, Dean D., Maric, Irina
Publicado 2023

Mast Cell Dependent Vascular Changes Associated with an Acute Response to Cold Immersion in Primary Contact Urticaria

por Meyer, Joseph, Gorbach, Alexander M., Liu, Wei-Min, Medic, Nevenka, Young, Michael, Nelson, Celeste, Arceo, Sarah, Desai, Avanti, Metcalfe, Dean D., Komarow, Hirsh D.
Publicado 2013

Preclinical human models and emerging therapeutics for advanced systemic mastocytosis

por Arock, Michel, Wedeh, Ghaith, Hoermann, Gregor, Bibi, Siham, Akin, Cem, Peter, Barbara, Gleixner, Karoline V., Hartmann, Karin, Butterfield, Joseph H., Metcalfe, Dean D., Valent, Peter
Publicado 2018

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis

por Kim, Do-Kyun, Beaven, Michael A., Kulinski, Joseph M., Desai, Avanti, Bandara, Geethani, Bai, Yun, Prussin, Calman, Schwartz, Lawrence B., Komarow, Hirsh, Metcalfe, Dean D., Olivera, Ana
Publicado 2016

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

por Tobío, Araceli, Bandara, Geethani, Morris, Denise A., Kim, Do-Kyun, O’Connell, Michael P., Komarow, Hirsh D., Carter, Melody C., Smrz, Daniel, Metcalfe, Dean D., Olivera, Ana
Publicado 2020

Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation

por Kim, Do-Kyun, Bandara, Geethani, Cho, Young-Eun, Komarow, Hirsh D., Donahue, Danielle R., Karim, Baktiar, Baek, Moon-Chang, Kim, Ho Min, Metcalfe, Dean D., Olivera, Ana
Publicado 2021

Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy

por Fereydouni, Mohammad, Ahani, Elnaz, Desai, Parth, Motaghed, Mona, Dellinger, Anthony, Metcalfe, Dean D., Yin, Yuzhi, Lee, Sung Hyun, Kafri, Tal, Bhatt, Aadra P., Dellinger, Kristen, Kepley, Christopher L.
Publicado 2022

Glycomic analysis of human mast cells, eosinophils and basophils

por North, Simon J, von Gunten, Stephan, Antonopoulos, Aristotelis, Trollope, Alana, MacGlashan, Donald W, Jang-Lee, Jihye, Dell, Anne, Metcalfe, Dean D, Kirshenbaum, Arnold S, Bochner, Bruce S, Haslam, Stuart M
Publicado 2012