Pharmacological manipulation of AID

por Methot, Stephen P., Di Noia, Javier M.
Publicado 2015

Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

por Padeken, Jan, Methot, Stephen P., Gasser, Susan M.
Publicado 2022

Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression

por Padeken, Jan, Methot, Stephen, Zeller, Peter, Delaney, Colin E., Kalck, Veronique, Gasser, Susan M.
Publicado 2021

Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65

por Delaney, Colin E., Methot, Stephen P., Guidi, Micol, Katic, Iskra, Gasser, Susan M., Padeken, Jan
Publicado 2019

Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression

por Padeken, Jan, Zeller, Peter, Towbin, Benjamin, Katic, Iskra, Kalck, Veronique, Methot, Stephen P., Gasser, Susan M.
Publicado 2019

SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity

por Delaney, Colin E., Methot, Stephen P., Kalck, Veronique, Seebacher, Jan, Hess, Daniel, Gasser, Susan M., Padeken, Jan
Publicado 2022

Author Correction: SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity

por Delaney, Colin E., Methot, Stephen P., Kalck, Veronique, Seebacher, Jan, Hess, Daniel, Gasser, Susan M., Padeken, Jan
Publicado 2022

Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm

por Methot, Stephen P., Litzler, Ludivine C., Trajtenberg, Felipe, Zahn, Astrid, Robert, Francis, Pelletier, Jerry, Buschiazzo, Alejandro, Magor, Brad G., Di Noia, Javier M.
Publicado 2015

Targeting the Tumour Vasculature: Exploitation of Low Oxygenation and Sensitivity to NOS Inhibition by Treatment with a Hypoxic Cytotoxin

por Baker, Jennifer H. E., Kyle, Alastair H., Bartels, Kirsten L., Methot, Stephen P., Flanagan, Erin J., Balbirnie, Andrew, Cran, Jordan D., Minchinton, Andrew I.
Publicado 2013

H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity

por Methot, Stephen P., Padeken, Jan, Brancati, Giovanna, Zeller, Peter, Delaney, Colin E., Gaidatzis, Dimos, Kohler, Hubertus, van Oudenaarden, Alexander, Großhans, Helge, Gasser, Susan M.
Publicado 2021

PRMT5 is essential for B cell development and germinal center dynamics

por Litzler, Ludivine C., Zahn, Astrid, Meli, Alexandre P., Hébert, Steven, Patenaude, Anne-Marie, Methot, Stephen P., Sprumont, Adrien, Bois, Thérence, Kitamura, Daisuke, Costantino, Santiago, King, Irah L., Kleinman, Claudia L., Richard, Stéphane, Di Noia, Javier M.
Publicado 2019

A licensing step links AID to transcription elongation for mutagenesis in B cells

por Methot, Stephen P., Litzler, Ludivine C., Subramani, Poorani Ganesh, Eranki, Anil K., Fifield, Heather, Patenaude, Anne-Marie, Gilmore, Julian C., Santiago, Gabriel E., Bagci, Halil, Côté, Jean-François, Larijani, Mani, Verdun, Ramiro E., Di Noia, Javier M.
Publicado 2018

Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice

por Litzler, Ludivine C., Zahn, Astrid, Dionne, Kiersten L., Sprumont, Adrien, Ferreira, Silvana R., Slattery, Michael R.F., Methot, Stephen P., Patenaude, Anne-Marie, Hébert, Steven, Kabir, Nisha, Subramani, Poorani Ganesh, Jung, Seolkyoung, Richard, Stéphane, Kleinman, Claudia L., Di Noia, Javier M.
Publicado 2023