Compensatory trans‐regulatory alleles minimizing variation in TDH3 expression are common within Saccharomyces cerevisiae

por Metzger, Brian P. H., Wittkopp, Patricia J.
Publicado 2019

The simplicity of protein sequence-function relationships

por Park, Yeonwoo, Metzger, Brian P.H., Thornton, Joseph W.
Publicado 2023

Evolutionary Dynamics of Regulatory Changes Underlying Gene Expression Divergence among Saccharomyces Species

por Metzger, Brian P.H., Wittkopp, Patricia J., Coolon, Joseph. D.
Publicado 2017

Selection on noise constrains variation in a eukaryotic promoter

por Metzger, Brian P. H., Yuan, David C., Gruber, Jonathan D., Duveau, Fabien, Wittkopp, Patricia J.
Publicado 2015

A hydrophobic ratchet entrenches molecular complexes

por Hochberg, Georg K.A., Liu, Yang, Marklund, Erik G., Metzger, Brian P. H., Laganowsky, Arthur, Thornton, Joseph W.
Publicado 2020

Mapping Small Effect Mutations in Saccharomyces cerevisiae: Impacts of Experimental Design and Mutational Properties

por Duveau, Fabien, Metzger, Brian P. H., Gruber, Jonathan D., Mack, Katya, Sood, Natasha, Brooks, Tiffany E., Wittkopp, Patricia J.
Publicado 2014